Summary Attributions

Line Name: Xtr.mlomZimml

Line Images [+] show captions [-] hide captions Xtr.mlo tadpole, also known as 'mrs lot' phenotype. ENU-mutants exhibits paralysis and motor neuron defects. Neural tissue of mlo and diploid control was stained with the HNK-1 antibody. In wild-type tadpoles motor neuron axons travel down the intermyotomal cleft from the neural tube; in mlo ([B] and [D]) the axonal tracts (black arrow) wander away from the intermyotomal space.

Summary
Synonym:	Mrs lot, mlo mh19 F3-C, T143-C, Xtr.mlo
Species:	Xenopus tropicalis
Background Strain:	Xtr.Nigerian1EXRC
Paternal Line:
Maternal Line:
Description:	Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations. Maps to a genetic interval containing the titin (ttn) gene.
Phenotype Description:	Homozygous mutants are completely paralyzed with no heartbeat.
Color Morph:	pigmented
Breeding Type:	OUTBRED
Lab of Origin:	Zimmerman Lab
Line Type:	Mutant
Mutated Gene(s):	unknown
MTA Required:	Yes
Public:	Yes
Catalogue Number:

Stock Center	RRID	Generation	Availability	Mutant Details
NXR (US)
EXRC (Europe)	EXRC_6012
NBRP (Japan)
XLRRI (US)

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