Search Lines and Strains
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| Line Name | Species | Mutated Gene(s) | Description | Availability |
| Xtr.zmym4emNXR | X. tropicalis | zmym4 | CRISPR KO of zmym4 (zinc finger MYM-type containing 4) in X. tropicalis. Germline transmission confi... | |
| Xtr.zeb2emNXR | X. tropicalis | zeb2 | CRISPR KO of zeb2 (zinc finger E-box binding homeobox 2), a gene associated with Mowat-Wilson syndro... | |
| Xtr.zbtb21emHorb | X. tropicalis | zbtb21 | CRISPR knockout of zbtb21(zinc finger and BTB domain containing 21), Current mosaic founders, Not te... | |
| Xtr.zbtb14emHorb | X. tropicalis | zbtb14 | CRISPR knockout of zbtb14 (zinc finger and BTB domain containing 14). Germ line transmission confirm... | |
| Xtr.ywhazemNXR | X. tropicalis | ywhaz | CRISPR KO of ywhaz (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). ge... | |
| Xtr.xbp1emNXR | X. tropicalis | xbp1 | CRISPR KO of xbp1 ( X-box binding protein 1 ) a gene assocaited with Major Affected Disorder in huma... | |
| Xtr.wwoxemHorb | X. tropicalis | wwox | CRISPR knockout of wwox (WW domain containing oxidoreductase), a gene associated with esophageal can... | |
| Xtr.wt1emHorb | X. tropicalis | wt1 | CRISPR knockout of wt1 (Wilms tumor 1). Germ line transmission confirmed. Animals carry a 5bp deleti... | |
| Xtr.wnt11bemNXR | X. tropicalis | wnt11b | CRISPR knockout of wnt11b (wingless-type MMTV integration site family, member 11B ), Germ line tran... | |
| Xtr.wbp11emNXR | X. tropicalis | wbp11 | CRISPR knockout of wbp11 (WW domain binding protein 11). Germline transmission confirmed, F2s growin... | |
| Xtr.vwa2emNXR | X. tropicalis | vwa2 | CRISPR knock out of vwa2 (von Willebrand factor A domain containing 2 ). Germ line transmission conf... | |
| Xtr.vangl2emNXR | X. tropicalis | vangl2 | CRISPR knockout of vangl2 (VANGL planar cell polarity protein 2 ), a gene associated with neural tub... | |
| Xtr.unc45bmZimml | X. tropicalis | unc45b | Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations. | |
| Xtr.tyremOchi | X. tropicalis | tyr | An albino line with CRISPR/Cas9-targeted mutation in tyrosinase (tyr) gene, made by the Ochi Lab. Th... | NBRP |
| Xtr.tyremNXR | X. tropicalis | tyr | CRISPR knockout of tyr (tyrosinase), Confirmed germline transmission. Animal carry a 241bp insertion... | |
| Xtr.tyremKtsz | X. tropicalis | tyr | An albino line with CRISPR/Cas9-targeted mutation in tyrosinase (tyr) gene, made by the Suzuki Lab. ... | NBRP |
| Xtr.tupmZimml | X. tropicalis | unknown | Mutation affecting axial development identified in the Mill Hill screen of ENU-induced mutations. | |
| Xtr.tspan8em3Horb | X. tropicalis | tspan8 | CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 3rd of 3 tspan lines at... | |
| Xtr.tspan8em2Horb | X. tropicalis | tspan8 | CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 2nd of 3 tspan lines at... | |
| Xtr.tspan8em1Horb | X. tropicalis | tspan8 | CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 1of 3 tspan lines at th... | |
| Xtr.tp53em_del2/+_Vlemx | X. tropicalis | tp53 | Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deletio... | |
| Xtr.tp53em_del1/em_del2_Vlemx | X. tropicalis | tp53 | Two types of F1 tp53 heterozygotes, each with a distinct variant of a deletion (em_del1/+ and em_del... | |
| Xtr.tp53em_del1/+_Vlemx | X. tropicalis | tp53 | Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deleti... | |
| Xtr.tlx3em2Horb | X. tropicalis | tlx3 | CRISPR mutant line targeting tlx3 (T cell leukemia homeobox 3). Germ lIne transmission was confirmed... | |
| Xtr.tlx3em1Horb | X. tropicalis | tlx3 | CRISPR knockout of tlx3 (T cell leukemia homeobox 3). Confirmed germline transmission. Custom mutant... | |
| Xtr.thratm,thrbtmShiyb | X. tropicalis | thra thrb | Double knockout oth thyroid receptor alpha nd thyroid receptor bets. Produced in the lab of Yun-Bo S... | |
| Xtr.thratmShiyb | X. tropicalis | thra | This line was created using TALENS targeting exon 4 (the third coding exon) of the X. tropicalis thr... | |
| Xtr.Tg(mlc2:dnfosl1-eGFP)Qi | X. tropicalis | fosl1 | Fosl1 protein was mutated and truncated to generate 3 mutant polypeptides which then cloned into pc... | |
| Xtr.tdrd1emNXR | X. tropicalis | tdrd1 | CRISPR knockout of tdrd1 (tudor domain containing 1). Germline transmission not yet confirmed. growi... | |
| Xtr.tbxtemJcsm | X. tropicalis | tbxt | Talen-induced 2bp deletion in exon 1 of tbxt (T-box transcription factor T) gene. Mutation destroys ... | |
| Xtr.tbxt.2em2Jcsm | X. tropicalis | tbxt.2 | Talen-induced mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... | |
| Xtr.tbxt.2em1Jcsm | X. tropicalis | tbxt.2 | Talen-mediated mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... | |
| Xtr.tbxt,tbxt.2emJcsm | X. tropicalis | tbxt | Double talen-induced mutant line. Talen induced 2-bp deletion in exon 1 of tbxt and 7 bp deletion in... | |
| Xtr.tbx5emHorb | X. tropicalis | tbx5 | CRISPR knockout of tbx5 (T-box 5 ), Confirmed germline transmission. Custom mutant generated by Horb... | |
| Xtr.tbx2emHorb | X. tropicalis | tbx2 | CRISPR knockout of tbx2 (T-box 2), Current mosaic founders, Not tested for germline transmission. | |
| Xtr.supt5hmZimml | X. tropicalis | supt5h | Mutation affecting eye development and melanophore migration identified in the Mill Hill screen for ... | |
| Xtr.staremNXR | X. tropicalis | star | CRISPR knockout of STAR (steroidogenic acute regulatory protein). Germ line transmission not yet con... | |
| Xtr.srd5a3emNXR | X. tropicalis | srd5a3 | CRISPR knockout of srd5a3 (steroid 5 alpha-reductase 3), Germ line transmission confirmed. F1 growin... | |
| Xtr.srd5a2emNXR | X. tropicalis | srd5a2 | CRISPR knockout of srd5a2 (steroid 5 alpha-reductase 2), Confirmed germ line transmission. animals c... | |
| Xtr.sox3emHorb | X. tropicalis | sox3 | CRISPR knockout of sox3 (SRY-box 3), Current mosaic founders, Not tested for germline transmission. ... | |
| Xtr.sox2emHorb | X. tropicalis | sox2 | CRISPR knockout of sox2 (SRY-box 2). Custom mutant line. Germ line transmission confirmed. Animals c... | |
| Xtr.snai2emNXR | X. tropicalis | snai2 | CRISPR knockout of snai2 (snail family zinc finger 2) in X. tropicalis. Germ line transmission confi... | |
| Xtr.snai1emNXR | X. tropicalis | snai1 | CRISPR knockout of snai1 (snail family zinc finger 1) in X. tropicalis. germline transmission confir... | |
| Xtr.smad4mZimml | X. tropicalis | smad4 | Mutation affecting haematopoiesis identified in a screen for ENU-induced mutations at Mill Hill. Pos... | |
| Xtr.slc2a7.tyr.hps6tmHUARC | X. tropicalis | hps6 slc2a7 tyr | triple knock out (3KO) line generated by crossing mutant lines with KO of tyr, hps6, and slc2a7 | |
| Xtr.six1em2NXR | X. tropicalis | six1 | CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc... | |
| Xtr.six1em1NXR | X. tropicalis | six1 | CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc... | |
| Xtr.shroom3emHorb | X. tropicalis | shroom3 | CRISPR knockout of shroom3 (shroom family member 3), Current mosaic founders, Germ line transmissio... | |
| Xtr.sf3b4emNXR | X. tropicalis | sf3b4 | CRISPR knockout of sf3b4 (splicing factor 3b subunit 4) in X tropicalis. sf3b4 is a gene associated ... | |
| Xtr.rxrgemHorb | X. tropicalis | rxrg | Description: CRISPR knockout of rxrg (retinoid X receptor gamma). Confirmed germline transmission. C... |
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