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Line Name Species Mutated Gene(s) Description Availability
Xtr.cby1emNXR X. tropicalis cby1 TALEN knockout of cby1 (chibby homolog 1). Germ line transmission not confirmed. Mutation not charac... NXR
Xtr.cbsemNXR X. tropicalis cbs CRISPR knockout targeting cbs (cystathionine-beta-synthase). Germ line transmission not yet confirme... NXR
Xtr.cacna1hem2NXR X. tropicalis cacna1h CRISPR knockout of cacna1h (calcium channel, voltage-dependent, T type, alpha 1H subunit). Germline ... NXR
Xtr.cacna1hem1NXR X. tropicalis cacna1h CRISPR knockout of cacna1h (calcium channel, voltage-dependent, T type, alpha 1H subunit). Germline ... NXR
Xtr.bxemZimml X. tropicalis unknown Mutation affecting eye development identified in the Mill Hill screen for ENU-induced mutations.
Xtr.bunmZimml X. tropicalis unknown Mutation affecting the ear development identified in the Mill Hill screen for ENU-induced mutations.
Xtr.bicc1em2NXR X. tropicalis bicc1 CRISPR knockout of bicc1 (BicC family RNA binding protein 1). Germ line transmission confirmed and c... NXR
Xtr.bicc1em1NXR X. tropicalis bicc1 CRISPR mutant of bicc1 (BicC family RNA binding protein 1). Germline transmission has been confirmed... NXR
Xtr.bhlhe22emHorb X. tropicalis bhlhe22 CRISPR knockout of bhlhe22 (basic helix-loop-helix family member e22), Germ line transmission confir... NXR
Xtr.bhlhe22em2Horb X. tropicalis bhlhe22 CRISPR knockout of bhlhe22 (basic helix-loop-helix family member e22), Germ line transmission confir... NXR
Xtr.bcorem2Horb X. tropicalis bcor CRISPR knockout of bcor (BCL6 corepressor). Germline transmission confirmed. Animals carry a 1 base ... NXR
Xtr.bcorem1Horb X. tropicalis bcor CRISPR knockout of bcor (BCL6 corepressor). Germline transmission confirmed. Animals carry a 4 base ... NXR
Xtr.bace1emHorb X. tropicalis bace1 CRISPR knockout of bace1 (beta-site APP-cleaving enzyme 1). Germ line transmission confirmed. Animal... NXR
Xtr.bace1em2Horb X. tropicalis bace1 CRISPR knockout of bace1 (beta-site APP-cleaving enzyme 1). Germ line transmission confirmed. Animal... NXR
Xtr.atp7amZimml X. tropicalis atp7a A mutation affecting retinal epithelium identified in the Mill Hill screen for ENU-induced mutations...
Xtr.askmZimml X. tropicalis unknown Mutation affecting the formation of inner ear otoconia identified in the Mill Hill screen for ENU-in...
Xtr.ascl1emHorb X. tropicalis ascl1 CRISPR knockout of ascl1(achaete-scute family bHLH transcription factor 1). Confirmed germline trans... NXR
Xtr.arnt,arnt2emHorb X. tropicalis arnt arnt2 CRISPR knockout of arnt/arnt2 (aryl hydrocarbon receptor nuclear translocator). Germ line transmissi... NXR
Xtr.aremHorb X. tropicalis ar CRISPR knockout in ar (androgen receptor). Germ line transmission not yet confirmed. Contact the NXR... NXR
Xtr.app emNXR X. tropicalis app CRISPR knockout targeting app (amyloid beta precursor protein). Germ line transmission not yet confi... NXR
Xtr.apcMRCΔ1/+Vlemx X. tropicalis apc F0 apc mosaics generated by apc TALENs injection, were outcrossed with WT X. tropicalis, and offspri...
Xtr.ap3d1mZimml X. tropicalis ap3d1 Mutation affecting inner ear otoconia identified in the Mill Hill screen for ENU-induced mutations. ...
Xtr.amhr2emNXR X. tropicalis amhr2 CRISPR knockout of amhr2 (anti-Mullerian hormone receptor type II ). Confirmed germline transmission... NXR
Xtr.amhr2em2NXR X. tropicalis amhr2 CRISPR knockout of amhr2 (anti-Mullerian hormone receptor type II ). Germ line transmission not yet ... NXR
Xtr.amhem3NXR X. tropicalis amh CRISPR knockout lines targeting amh (anti-Mullerian hormone ) developed at the NXR. Confirmed germli... NXR
Xtr.amhem2NXR X. tropicalis amh CRISPR knockout line targeting amh (anti-Mullerian hormone). Confirmed germline transmission. Animal... NXR
Xtr.aif1lem2Horb X. tropicalis aif1l CRISPR knockout of aif1l (allograft inflammatory factor 1-like). Custom mutant generated by Horb Lab... NXR
Xtr.aif1lem1Horb X. tropicalis aif1l CRISPR knockout of aif1l (allograft inflammatory factor 1-like). Confirmed germline transmission. Cu... NXR
Xtr.ahrem2NXR X. tropicalis ahr TALEN generated mutant line targeting ahr (aryl hydrocarbon receptor). Germ line transmission confir... NXR
Xtr.ahrem1NXR X. tropicalis ahr TALEN generated mutant line targeting ahr (aryl hydrocarbon receptor). Germ line transmission confir... NXR
Xtr.acsl1emNXR X. tropicalis acsl1 CRISPR knockout of acsl1 (acyl-CoA synthetase long chain family member 1). Germ line transmission co...
Xla.xdm-wemNXR X. laevis dm-w.L CRISPR knock out of xdm-w (doublesex and mab3 related transcription factor W ). Germ Line transmissi...
Xla.wnt3em2NXR X. laevis wnt3.L X. laevis CRISPR line targeting wnt3.L (Wnt family member 3). Germ line transmission not yet confirm... NXR
Xla.wnt3em1NXR X. laevis wnt3.S X. laevis CRISPR line targeting wnt3.S (Wnt family member 3). Germ line transmission not yet confirm... NXR
Xla.wnt11emHorb X. laevis wnt11.L wnt11.S Double CRISPR knockout of wnt11 (Wnt family member 11) in X. laevis, Confirmed germline transmission... NXR
Xla.wnt11bemNXR X. laevis wnt11b.L CRISPR knockout of wnt11b (wingless-type MMTV integration site family, member 11B) in X laevis. Germ... NXR
Xla.wnt11b-/- X. laevis wnt11b.L Homozygote offspring from a cross between a homozygous wnt11b{-/-} mother and father. Also described...
Xla.wnt11b-/+ X. laevis wnt11b.L Heterozygote offspring from a cross between a homozygous wnt11b{-/-} mother and wildtype father. Als...
Xla.wnt11b+/- X. laevis wnt11b.L Heterozygote offspring from a cross between a homozygous wnt11b{-/-} father and wildtype mother. Als...
Xla.wdpcpemHorb X. laevis wdpcp.L CRISPR knockout of wdpcp (WD repeat containing planar cell polarity effector). Germ line transmissio... NXR
Xla.velo1emNXR X. laevis velo1.L X. laevis CRISPR line targeting velo1.L (velo1 protein). Mutation not yet characterized. Germ line... NXR
Xla.tyremNXR X. laevis tyr.L TALEN induced tyrosinase mutant. Custom line made by the NXR. Contact NXR for details.
Xla.trilemNXR X. laevis tril.S CRISPR knockout of tril (LR4 interactor with leucine-rich repeats). Germ line transmission confirmed... NXR
Xla.trilem2NXR X. laevis tril.L tril.S CRISPR knockout of tril (TLR4 interactor with leucine-rich repeats). Germline transmission not yet c... NXR
Xla.tracemHorb X. laevis trac.L CRISPR line targeting trac (T cell receptor alpha constant), a gene associated with immunodeficiency... NXR
Xla.tracem2Horb X. laevis trac.L trac.S CRISPR knockout of trac (T cell receptor alpha constant). Guide targeting S alloallele was injected ... NXR
Xla.thrbem3NXR X. laevis thrb.L thrb.S Double CRISPR mutant line of thrb (thyroid hormone receptor, beta). Germ line transmission confirmed... NXR
Xla.thrbem2NXR X. laevis thrb.S CRISPR knockout of thrb.S thyroid hormone receptor, beta S homolog). germline transmission confirmed... NXR
Xla.thrbem1NXR X. laevis thrb.L CRISPR knockout of thrb.L thyroid hormone receptor, beta L homolog). Germline transmission confirmed... NXR
Xla.tcf3emNXR X. laevis tcf3.L X. laevis CRISPR line targeting tcf3.L (transcription factor 3). Line in development. Contact NXR f...

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