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Xla.ar em1NXR
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X. laevis |
ar.L
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CRISPR mutation of ar (androgen receptor). Mutation is confirmed as a 13bp deletion in ar.L ( AGTGTG... |
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Xtr.amhr2emNXR
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X. tropicalis |
amhr2
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CRISPR knockout of amhr2 (anti-Mullerian hormone receptor type II ). Confirmed germline transmission... |
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Xtr.amhem3NXR
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X. tropicalis |
amh
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CRISPR knockout of amh (anti-Mullerian hormone ). Confirmed germline transmission. Custom mutant gen... |
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Xtr.amhem2NXR
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X. tropicalis |
amh
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CRISPR knockout of amh (anti-Mullerian hormone ). Confirmed germline transmission. Custom mutant: 5b... |
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Xtr.aif1lem2Horb
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X. tropicalis |
aif1l
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CRISPR knockout of aif1l (allograft inflammatory factor 1-like). Confirmed germline transmission. Cu... |
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Xla.ahremNXR
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X. laevis |
ahr.L
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Custom generated mutant made by NXR. Germ line transmission not yet confirmed. Contact NXR for detai... |
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Xtr.ahrem2NXR
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X. tropicalis |
ahr
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TALEN generated mutant line, made by the NXR. Germ line transmission confirmed. mutation: 7bp deleti... |
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Xtr.ahrem1NXR
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X. tropicalis |
ahr
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TALEN generated mutant line, made by the NXR. Germ line transmission confirmed. ,+2bp mutation: CCAT... |
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Xla.adam33emNXR
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X. laevis |
adam33.L
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CRISPR knockout of adam33 (ADAM metallopeptidase domain 33 ). Confirmed germline transmission. Anima... |
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Xtr.thratmShiyb
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X. tropicalis |
thra
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This line was created using TALENS targeting exon 4 (the third coding exon) of the X. tropicalis thr... |
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Xla.kcptmFlc
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X. laevis |
kcp.L
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One-cell stage Xenopus Xla.Tg(Cardiac-actin:GFP)Mohun embryos were microinjected with 1 ng TALEN mRN... |
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Xtr.tp53em_del1/em_del2_Vlemx
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X. tropicalis |
tp53
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Two types of F1 tp53 heterozygotes, each with a distinct variant of a deletion (em_del1/+ and em_del... |
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Xla.hps4m
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X. laevis |
hps4.L
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This periodic albino mutant of Xenopus laevis is a recessive mutant. Fukazawa et al 2020 showed that... |
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Xtr.tp53em_del2/+_Vlemx
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X. tropicalis |
tp53
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Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deletio... |
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Xtr.tp53em_del1/+_Vlemx
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X. tropicalis |
tp53
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Deletion is expected to give rise to nonsense-mediated
decay since due to the frame-shifting deleti... |
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Xla.runx1em(GFP)EXRC
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X. laevis |
runx1.L
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CRISPR-Cas9 mediated insertion of IRES-GFP sequence into the 3'-UTR of runx1 gene, |
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Xtr.tbxt,tbxt.2emJcsm
|
X. tropicalis |
tbxt
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Double talen-induced mutant line. Talen induced 2-bp deletion in exon 1 of tbxt and 7 bp deletion in... |
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Xtr.tbxt.2em2Jcsm
|
X. tropicalis |
tbxt.2
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Talen-induced mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... |
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Xtr.tbxt.2em1Jcsm
|
X. tropicalis |
tbxt.2
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Talen-mediated mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... |
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Xla.npffr1.1emEXRC
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X. laevis |
npffr1.1.L
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Crispr-Cas9 mutation in the npffr1.1 gene (neuropeptide FF receptor 1, gene 1 ). |
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Xtr.tbxtemJcsm
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X. tropicalis |
tbxt
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Talen-induced 2bp deletion in exon 1 of tbxt (T-box transcription factor T) gene. Mutation destroys ... |
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Xtr.oc90mZimml
|
X. tropicalis |
oc90
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Mutation affecting inner ear otoconia identified in the Mill Hill screen for ENU-induced mutations. ... |
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Xtr.ap3d1mZimml
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X. tropicalis |
ap3d1
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Mutation affecting inner ear otoconia identified in the Mill Hill screen for ENU-induced mutations. ... |
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Xtr.atp7amZimml
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X. tropicalis |
atp7a
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A mutation affecting retinal epithelium identified in the Mill Hill screen for ENU-induced mutations... |
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Xtr.supt5hmZimml
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X. tropicalis |
supt5h
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Mutation affecting eye development and melanophore migration identified in the Mill Hill screen for ... |
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Xtr.petmZimml
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X. tropicalis |
unknown
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Homozygous mutants are completely paralyzed with no heartbeat. |
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Xtr.mlomZimml
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X. tropicalis |
unknown
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Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations. Map... |
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Xtr.unc45bmZimml
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X. tropicalis |
unc45b
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Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations. |
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Xtr.smad4mZimml
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X. tropicalis |
smad4
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Mutation affecting haematopoiesis identified in a screen for ENU-induced mutations at Mill Hill. Pos... |
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Xtr.askmZimml
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X. tropicalis |
unknown
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Mutation affecting the formation of inner ear otoconia identified in the Mill Hill screen for ENU-in... |
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Xtr.bxemZimml
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X. tropicalis |
unknown
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Mutation affecting eye development identified in the Mill Hill screen for ENU-induced mutations. |
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Xtr.mammZimml
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X. tropicalis |
unknown
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Mutation affecting cardiac function identified in a screen for ENU-induced mutations at Mill Hill |
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Xtr.bunmZimml
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X. tropicalis |
unknown
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Mutation affecting the ear development identified in the Mill Hill screen for ENU-induced mutations. |
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Xtr.dstmZimml
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X. tropicalis |
unknown
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Mutation affecting the haematopoietic system identified in the Mill Hill screen for ENU-induced muta... |
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Xtr.tupmZimml
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X. tropicalis |
unknown
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Mutation affecting axial development identified in the Mill Hill screen of ENU-induced mutations. |
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Xtr.legmZimml
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X. tropicalis |
unknown
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Mutation affecting otoconia formation identified in the Mill Hill screen of ENU-induced mutations. |
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Xtr.runx2emHorb
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X. tropicalis |
runx2
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CRISPR knockout of runx2 (runt related transcription factor 2). Contact NXR to inquire about availab... |
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Xtr.wwoxemHorb
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X. tropicalis |
wwox
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CRISPR knockout of wwox (WW domain containing oxidoreductase), a gene associated with esophageal can... |
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Xtr.amhem1NXR
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X. tropicalis |
amh
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CRISPR knockout of amh (anti-Mullerian hormone). Germline transmission confirmed. +8bp mutation in a... |
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Xtr.gfi1em1Horb
|
X. tropicalis |
gfi1
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CRISPR knockout of gfi1 (growth factor independent 1 transcription repressor). Germ line transmissio... |
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Xtr.sox2emHorb
|
X. tropicalis |
sox2
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CRISPR knockout of sox2 (SRY-box 2). Custom mutant line. Germ line transmission confirmed. Animals c... |
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Xtr.otx2emHorb
|
X. tropicalis |
otx2
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CRISPR knockout of otx2 (orthodenticle homeobox 2). Germ line transmission confirmed. Animals carry ... |
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Xtr.kcnj11emHorb
|
X. tropicalis |
kcnj8
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CRISPR knockout of kcnj11 (potassium channel, inwardly rectifying subfamily J, member 11). Germline ... |
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Xtr.bcorem1Horb
|
X. tropicalis |
bcor
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CRISPR knockout of bcor (BCL6 corepressor). Germline transmission confirmed. Mutation is a 4bp delet... |
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Xtr.nhlh1emHorb
|
X. tropicalis |
nhlh1
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CRISPR knockout of nhlh1 (nescient helix-loop-helix 1). Germ line transmission confirmed. Mutation b... |
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Xtr.wt1emHorb
|
X. tropicalis |
wt1
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CRISPR knockout of wt1 (Wilms tumor 1). Germ line transmission confirmed. Animals carry a 5bp deleti... |
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Xla.pkhd1emHorb
|
X. laevis |
pkhd1.L
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CRISPR knockout of pkhd1 (PKHD1, fibrocystin/polyductin), Germ line transmission confirmed. Animals ... |
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Xla.pkd1em1Horb
|
X. laevis |
pkd1.L
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CRISPR knockout of pkd1 (polycystin 1, transient receptor potential channel interacting). Germ line... |
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Xtr.foxb1em1Horb
|
X. tropicalis |
foxb1
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CRISPR knockout of foxb1 (forkhead box B1 ), Current mosaic founders, germline transmission confirme... |
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Xtr.dtlemHorb
|
X. tropicalis |
dtl
|
CRISPR knockout of dtl (denticleless E3 ubiquitin protein ligase homolog), Current mosaic founders, ... |
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