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Line Name Species Mutated Gene(s) Description Availability
Xla.wnt11b+/- X. laevis wnt11b.L Heterozygote offspring from a cross between a homozygous wnt11b{-/-} father and wildtype mother. Als...
Xla.wnt11b-/- X. laevis wnt11b.L Homozygote offspring from a cross between a homozygous wnt11b{-/-} mother and father. Also described...
Xla.wnt11b-/+ X. laevis wnt11b.L Heterozygote offspring from a cross between a homozygous wnt11b{-/-} mother and wildtype father. Als...
Xtr.icam5em2Horb X. tropicalis icam5 2nd Xtropicalis line with CRISPR knockout of icam5 (intercellular adhesion molecule 5), Germ line tr... NXR
Xtr.hs6st1emNXR X. tropicalis hs6st1 CRISPR knockout of hs6st1 (heparan sulfate 6-O-sulfotransferase 1). Germ line transmission not yet c... NXR
Xla.dmrt1em4NXR X. laevis dmrt1.L dmrt1.S Double X. laevis CRISPR knockout line, targeting both dmrt1.S and dmrt1.L (doublesex and mab-3 relat... NXR
Xtr.cbsemNXR X. tropicalis cbs CRISPR knockout targeting cbs (cystathionine-beta-synthase). Germ line transmission not yet confirme... NXR
Xtr.snai2em3NXR X. tropicalis snai2 3rd CRISPR knockout line targeting snai2 (snail family zinc finger 2) in X. tropicalis. Germ line tr... NXR
Xtr.snai2 em2NXR X. tropicalis snai2 CRISPR knockout of snai2 (snail family zinc finger 2) in X. tropicalis. Germ line transmission confi... NXR
Xtr.sobpem2NXR X. tropicalis sobp CRISPR knockout of sobp (sine oculis binding protein homolog). Germline transmission confirmed. Anim... NXR
Xtr.syngap1 emNXR X. tropicalis syngap1 CRISPR knockout targeting syngap1 (synaptic Ras GTPase activating protein 1). Germline transmission ... NXR
Xla.tcf3emNXR X. laevis tcf3.L X. laevis CRISPR line targeting tcf3.L (transcription factor 3). Line in development. Contact NXR f...
Xla.tbx21emNXR X. laevis tbx21.L tbx21.S Double CRISPR KO line targeting tbx21.L and tbx21.S in X. laevis. Germ line transmission confirmed. ... NXR
Xla.tap2emNXR X. laevis tap2.L X. laevis CRISPR line targeting tap2 (transporter 2, ATP-binding cassette, sub-family B (MDR/TAP). G... NXR
Xla.tap1emNXR X. laevis tap1.L X. laevis CRISPR line targeting tap1 (transporter 1, ATP-binding cassette, sub-family B (MDR/TAP). G... NXR
Xla.tracemHorb X. laevis trac.L CRISPR line targeting trac (T cell receptor alpha constant), a gene associated with immunodeficiency... NXR
Xla.velo1emNXR X. laevis velo1.L X. laevis CRISPR line targeting velo1.L (velo1 protein). Mutation not yet characterized. Germ line... NXR
Xla.wnt3em2NXR X. laevis wnt3.L X. laevis CRISPR line targeting wnt3.L (Wnt family member 3). Germ line transmission not yet confirm... NXR
Xla.wnt3em1NXR X. laevis wnt3.S X. laevis CRISPR line targeting wnt3.S (Wnt family member 3). Germ line transmission not yet confirm... NXR
Xtr.wnt3em1NXR X. tropicalis wnt3 CRISPR line targeting wnt3 (Wnt family member 3). Germ line transmission not yet confirmed. Contact ... NXR
Xtr.xbp1em2NXR X. tropicalis xbp1 2nd X. tropicalis CRISPR line for xbp1 (X-box binding protein 1). Germ line transmission has been co... NXR
Xtr.sox2em2Horb X. tropicalis sox2 CRISPR knockout of sox2 (SRY-box 2). Custom mutant line. Germ line transmission confirmed. Animals c... NXR
Xtr.shroom3em2Horb X. tropicalis shroom3 CRISPR knockout of shroom3 (shroom family member 3). Germ line transmission confirmed. Animals carry... NXR
Xla.plekhg3emNXR X. laevis plekhg3.L CRISPR knockout targeting plekhg3.L (pleckstrin homology and RhoGEF domain containing G3) gene. Germ... NXR
Xtr.ripply3em2NXR X. tropicalis ripply3 2nd of 2 ripply3 lines at the NXR, CRISPR KO of ripply3 (ripply transcriptional repressor 3). Germ l... NXR
Xtr.ripk4emNXR X. tropicalis ripk4 CRISPR knockout targeting ripk4 (receptor interacting serine/threonine kinase 4). Germline transmiss... NXR
Xtr.prph2em2Horb X. tropicalis prph2 CRISPR knockout of prph2 (peripherin 2). Confirmed germ line transmission. Animals carry a 4 base pa... NXR
Xtr.pou4f1em2NXR X. tropicalis pou4f1 CRISPR knockout in pou4f1 (POU class 4 homeobox 1) gene. Germline transmission confirmed. Animals ca... NXR
Xtr.edn3 em NXR X. tropicalis edn3 X. tropicalis CRISPR line knock out of edn3 (endothelin-3). Germ line transmission not yet confirmed... NXR
Xla.pkhd1em3Horb X. laevis pkhd1.L CRISPR knockout of pkhd1 (PKHD1, fibrocystin/polyductin), Germ line transmission confirmed. Animals ... NXR
Xla.pkhd1em2Horb X. laevis pkhd1.L CRISPR knockout of pkhd1 (PKHD1, fibrocystin/polyductin), Germ line transmission confirmed. Animals ... NXR
Xla.pax7em2Horb X. laevis pax7.L pax7.S CRISPR knockout of pax7 (paired box). Germ line transmission confirmed. Animals carry a 22 base pair... NXR
Xtr.notch4 em2Horb X. tropicalis notch4 CRISPR knockout of notch4 in X. tropicalis. Confirmed germline transmission. Mutation characterized:... NXR
Xtr.eomesem2Horb X. tropicalis eomes CRISPR knockout of eomes (eomesodermin). Germline transmission confirmed. Animals carry a 4 base pai... NXR
Xtr.bicc1em2NXR X. tropicalis bicc1 CRISPR knockout of bicc1 (BicC family RNA binding protein 1). Germ line transmission confirmed and c... NXR
Xtr.app emNXR X. tropicalis app CRISPR knockout targeting app (amyloid beta precursor protein). Germ line transmission not yet confi... NXR
Xtr.slc2a7tm,tyrtm,hps6tmHUARC X. tropicalis hps6 slc2a7 tyr triple knock out (3KO) line generated by crossing mutant lines with KO of tyr, hps6, and slc2a7
Xtr.thratm,thrbtmShiyb X. tropicalis thra thrb Double knockout oth thyroid receptor alpha nd thyroid receptor bets. Produced in the lab of Yun-Bo S...
Xtr.tyremOchi X. tropicalis tyr An albino line with CRISPR/Cas9-targeted mutation in tyrosinase (tyr) gene, made by the Ochi Lab. Th... NBRP
Xtr.tyremKtsz X. tropicalis tyr An albino line with CRISPR/Cas9-targeted mutation in tyrosinase (tyr) gene, made by the Suzuki Lab. ... NBRP
Xtr.hps6emOgino X. tropicalis hps6 CRISPR/Cas9-mediated targeted mutation in hsp6, a gene resonsible for X. tropicalis no privacy (nop)... NBRP
Xla.pkd1emHorb X. laevis pkd1.L CRISPR knockout of pkd1 (polycystin 1, transient receptor potential channel interacting). Germ line ... NXR
Xla.prkdcem2NXR X. laevis prkdc.L CRISPR KO of prkdc (protein kinase, DNA-activated, catalytic subunit ). Germ line transmission confi... NXR
Xla.tcf3em2NXR X. laevis tcf3.S CRISPR knockout of tcf3.S ( transcription factor 3). Germ line transmission not yet confirmed. Cont... NXR
Xtr.staremNXR X. tropicalis star CRISPR knockout of STAR (steroidogenic acute regulatory protein). Germ line transmission not yet con... NXR
Xtr.foxb1em2Horb X. tropicalis foxb1 CRISPR knockout of foxb1 (forkhead box B1 ), Current mosaic founders, germline transmission confirme... NXR
Xtr.gdf1em2Horb X. tropicalis gdf1 CRISPR knockout of gdf1 (growth differentiation factor 1). Confirmed germline transmission. Custom ... NXR
Xla.il2rgem2NXR X. laevis il2rg.L CRISPR knockout of il2rg (interleukin 2 receptor subunit gamma). Germ line transmission confirmed. A... NXR
Xtr.acsl1emNXR X. tropicalis acsl1 CRISPR knockout of acsl1 (acyl-CoA synthetase long chain family member 1). Germ line transmission co...
Xtr.nagluem2NXR X. tropicalis naglu CRISPR knockout of naglu (N-acetyl-alpha-glucosaminidase). Germ line transmission confirmed. Animals... NXR

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