Search Lines and Strains
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| Line Name | Species | Mutated Gene(s) | Description | Availability |
| Xtr.nagluem1NXR | X. tropicalis | naglu | CRISPR knockout of naglu (N-acetyl-alpha-glucosaminidase) gene. Germ line transmission confirmed. An... | NXR |
| Xtr.lamp2emHorb | X. tropicalis | lamp2 | CRISPR knockout of lamp2 (lysosomal associated membrane protein 2 ). Germ line transmission confirme... | NXR |
| Xtr.lamp2em2Horb | X. tropicalis | lamp2 | CRISPR knockout of lamp2 (lysosomal associated membrane protein 2 ). Germ line transmission confirme... | NXR |
| Xla.rag2emNXR | X. laevis | rag2.L | CRISPR knockout of rag2 (recombination activating 2). Germ line transmission confirmed. Animals carr... | NXR |
| Xla.foxn1em2NXR | X. laevis | foxn1.L | CRISPR knockout of foxn1.L (forkhead box N1). Germ line transmission confirmed. Animals carry a 2 ba... | NXR |
| Xla.foxn1em1NXR | X. laevis | foxn1.L | CRISPR knockout of foxn1.L (forkhead box N1). Germ line transmission confirmed, F1s established. Ani... | NXR |
| Xla.acsl5.LemNXR | X. laevis | acsl5.L | CRISPR knock out of acsl5 (acyl-CoA synthetase long chain family member 5 ). Germ line transmission ... | NXR |
| Xtr.meis1emNXR | X. tropicalis | meis1 | CRISPR knockout of meis1 (meis homeobox 1). Germline transmission confirmed. Animals carry a 51 base... | NXR |
| Xla.rykemNXR | X. laevis | ryk.S | CRISPR knockout of ryk.S (receptor like tyrosine kinase S homeolog). Germline transmission not yet c... | NXR |
| Xla.cxcl8bemNXR | X. laevis | cxcl8b.2.L | CRISPR knockout of cxcl8b (C-X-C motif chemokine ligand 8) and also known as il8b (interleukin-8). G... | NXR |
| Xla.cxcl8aemNXR | X. laevis | cxcl8a.L | CRISPR knockout of cxcl8a (C-X-C motif chemokine ligand 8) and also known as il8a (interleukin-8). G... | NXR |
| Xtr.foxl2em2NXR | X. tropicalis | foxl2 | CRISPR knockout of foxl2 (forkhead box L2). Germline transmission confirmed. Animals carry a 1 base ... | NXR |
| Xtr.foxp3em2NXR | X. tropicalis | foxp3 | CRISPR knockout of foxp3 (forkhead box P3). Germ line transmission confirmed. Animals carry a 17 bas... | NXR |
| Xtr.fermt2tm-/- Huzha | X. tropicalis | fermt2 | This is a CRISPR generated mutant giving rise to a 10bp deletion in the fermt2/kindlin2 gene. | |
| Xtr.apcMRCΔ1/+Vlemx | X. tropicalis | apc | F0 apc mosaics generated by apc TALENs injection, were outcrossed with WT X. tropicalis, and offspri... | |
| Xtr.Tg(mlc2:dnfosl1-eGFP)Qi | X. tropicalis | fosl1 | Fosl1 protein was mutated and truncated to generate 3 mutant polypeptides which then cloned into pc... | |
| Xtr.mtnr1aemNXR | X. tropicalis | mtnr1a | CRISPR knock out of mtnr1a (melatonin receptor 1A ). Germ line transmission confirmed. Animals carry... | NXR |
| Xtr.six1em2NXR | X. tropicalis | six1 | CRISPR knockout of six1 (SIX homeobox 1). Germ line transmission confirmed. Animals carry a 28 base ... | NXR |
| Xtr.zmym4emNXR | X. tropicalis | zmym4 | CRISPR KO of zmym4 (zinc finger MYM-type containing 4). Germline transmission confirmed. Animals car... | NXR |
| Xtr.zeb2emNXR | X. tropicalis | zeb2 | CRISPR KO of zeb2 (zinc finger E-box binding homeobox 2). Germ line transmission not yet confirmed. ... | NXR |
| Xtr.ywhazemNXR | X. tropicalis | ywhaz | CRISPR KO of ywhaz (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). Ge... | NXR |
| Xtr.xbp1emNXR | X. tropicalis | xbp1 | CRISPR KO of xbp1 (X-box binding protein 1). Germ line transmission has been confirmed. Animals carr... | NXR |
| Xla.baz1bemNXR | X. laevis | baz1b.L | TALENs knockout of baz1b (bromodomain adjacent to zinc finger domain 1B ) aka 'wstf'. Germ line tran... | NXR |
| Xla.wnt11bemNXR | X. laevis | wnt11b.L | CRISPR knockout of wnt11b (wingless-type MMTV integration site family, member 11B) in X laevis. Germ... | NXR |
| Xtr.wnt11bemNXR | X. tropicalis | wnt11b | X. tropicalis CRISPR knockout of wnt11b (wingless-type MMTV integration site family, member 11B ), ... | NXR |
| Xtr.wbp11emNXR | X. tropicalis | wbp11 | CRISPR knockout of wbp11 (WW domain binding protein 11). Germline transmission confirmed. Animals ca... | NXR |
| Xtr.vwa2emNXR | X. tropicalis | vwa2 | CRISPR knock out of vwa2 (von Willebrand factor A domain containing 2 ). Germ line transmission conf... | NXR |
| Xtr.vangl2emNXR | X. tropicalis | vangl2 | CRISPR knockout of vangl2 (VANGL planar cell polarity protein 2). Germ line transmission not yet con... | NXR |
| Xtr.tspan8em2Horb | X. tropicalis | tspan8 | CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. Animals carry a 1 base ... | NXR |
| Xla.trilemNXR | X. laevis | tril.S | CRISPR knockout of tril (LR4 interactor with leucine-rich repeats). Germ line transmission confirmed... | NXR |
| Xla.thrbem3NXR | X. laevis | thrb.L thrb.S | Double CRISPR mutant line of thrb (thyroid hormone receptor, beta). Germ line transmission confirmed... | NXR |
| Xla.thrbem2NXR | X. laevis | thrb.S | CRISPR knockout of thrb.S thyroid hormone receptor, beta S homolog). germline transmission confirmed... | NXR |
| Xla.thrbem1NXR | X. laevis | thrb.L | CRISPR knockout of thrb.L thyroid hormone receptor, beta L homolog). Germline transmission confirmed... | NXR |
| Xtr.tdrd1emNXR | X. tropicalis | tdrd1 | CRISPR knockout of tdrd1 (tudor domain containing 1). Germline transmission not yet confirmed. Conta... | NXR |
| Xtr.srd5a3emNXR | X. tropicalis | srd5a3 | CRISPR knockout of srd5a3 (steroid 5 alpha-reductase 3), Germ line transmission confirmed. Animals c... | NXR |
| Xtr.srd5a2emNXR | X. tropicalis | srd5a2 | CRISPR knockout of srd5a2 (steroid 5 alpha-reductase 2). Confirmed germ line transmission. Animals c... | NXR |
| Xtr.sobpemNXR | X. tropicalis | sobp | CRISPR knockout of sobp (sine oculis binding protein homolog). Germline transmission confirmed. Anim... | NXR |
| Xtr.snai2emNXR | X. tropicalis | snai2 | CRISPR knockout of snai2 (snail family zinc finger 2) in X. tropicalis. Germ line transmission confi... | NXR |
| Xtr.snai1emNXR | X. tropicalis | snai1 | CRISPR knockout of snai1 (snail family zinc finger 1) in X. tropicalis. germline transmission confir... | NXR |
| Xtr.six1em1NXR | X. tropicalis | six1 | CRISPR knockout of six1 (SIX homeobox 1). Germ line transmission confirmed. Animals carry a 2 base p... | NXR |
| Xtr.sf3b4emNXR | X. tropicalis | sf3b4 | CRISPR knockout of sf3b4 (splicing factor 3b subunit 4). Germline transmission confirmed. Animals ca... | NXR |
| Xla.slc45a2emNXR | X. laevis | slc45a2.L | CRISPR knockout of slc45a2 (solute carrier family 45 member 2 ). Screened for germline transmission.... | NXR |
| Xtr.foxn1emHuarc | X. tropicalis | foxn1 | An athymic line with TALEN-mediated targeted mutation in foxn1 gene, made by the Yaoita Lab. Absence... | NBRP |
| Xtr.rxraemNXR | X. tropicalis | rxra | CRISPR knockout of rxra (retinoid X receptor alpha ). Germ line transmission confirmed. Animals carr... | NXR |
| Xtr.runx1em2NXR | X. tropicalis | runx1 | CRISPR knockout of runx1 (runt related transcription factor 1). Germ line transmission confirmed. An... | NXR |
| Xtr.rspo2emNXR | X. tropicalis | rspo2 | CRISPR knockout of rspo2 (R-spondin 2). Germ line transmission confirmed. Animals carry a 5 base pai... | NXR |
| Xtr.ror2emNXR | X. tropicalis | ror2 | CRISPR knockout of ror2 (receptor tyrosine kinase like orphan receptor 2). Germ line transmission no... | NXR |
| Xtr.ripply3emNXR | X. tropicalis | ripply3 | CRISPR KO of ripply3 (ripply transcriptional repressor 3). Germ line transmission confirmed. Animal... | NXR |
| Xtr.rfx6emNXR | X. tropicalis | rfx6 | CRISPR KO of rfx6 (regulatory factor X6) in X. tropicalis. Germ line transmission confirmed. Anim... | NXR |
| Xtr.rflciiemNXR | X. tropicalis | rflcii | CRISPR knockout of rflcii (relaxin family locus C type II ) in X tropicalis. Germ line transmission ... | NXR |
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