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Results 101 - 150 of 230 results

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Line Name Species Mutated Gene(s) Description Availability
Xla.csf3remNXR X. laevis csf3r.L CRISPR knockout of csf3r (colony stimulating factor 3 receptor ). Germ line transmission not yet con...
Xtr.cby1emNXR X. tropicalis cby1 TALEN knockout of cby1 (chibby homolog 1). Germ line transmission not confirmed. Mutation not charac...
Xtr.celf3emNXR X. tropicalis celf3 CRISPR knock out of celf3 (CUGBP, Elav-like family member 3). Germ line transmission not yet confirm...
Xla.ccdc78emNXR X. laevis ccdc78.S CRISPR knockout of ccdc78 (coiled-coil domain containing 78). Germ line transmission confirmed. Muta...
Xtr.cacna1hem2NXR X. tropicalis cacna1h CRISPR knockout of cacna1h (calcium channel, voltage-dependent, T type, alpha 1H subunit). Mutation ...
Xtr.cacna1hem1NXR X. tropicalis cacna1h CRISPR knockout of cacna1h (calcium channel, voltage-dependent, T type, alpha 1H subunit). Mutation ...
Xtr.bicc1em1NXR X. tropicalis bicc1 CRISPR mutant of bicc1 (BicC family RNA binding protein 1). Germline transmission has been confirmed...
Xtr.bcorem4Horb X. tropicalis bcor CRISPR knockout of bcor (BCL6 corepressor). Germline transmission confirmed. Mutation is a 11bp dele...
Xtr.bcorem3Horb X. tropicalis bcor CRISPR knockout of bcor (BCL6 corepressor). Germline transmission confirmed. Mutation is a 5bp delet...
Xtr.bcorem2Horb X. tropicalis bcor CRISPR knockout of bcor (BCL6 corepressor). Germline transmission confirmed. Mutation is a 1bp delet...
Xla.arntlemNXR X. laevis bmal1.L CRISPR knockout of arntl (arbon receptor nuclear translocator like). Germline transmission confirme...
Xla.arem2NXR X. laevis ar.L CRISPR mutation of ar (androgen receptor). Mutation is confirmed as a 19bp deletion in ar.L (GAGTGTG...
Xla.ar em1NXR X. laevis ar.L CRISPR mutation of ar (androgen receptor). Mutation is confirmed as a 13bp deletion in ar.L ( AGTGTG...
Xtr.amhr2emNXR X. tropicalis amhr2 CRISPR knockout of amhr2 (anti-Mullerian hormone receptor type II ). Confirmed germline transmission...
Xtr.amhem3NXR X. tropicalis amh CRISPR knockout of amh (anti-Mullerian hormone ). Confirmed germline transmission. Custom mutant gen...
Xtr.amhem2NXR X. tropicalis amh CRISPR knockout of amh (anti-Mullerian hormone ). Confirmed germline transmission. Custom mutant: 5b...
Xtr.aif1lem2Horb X. tropicalis aif1l CRISPR knockout of aif1l (allograft inflammatory factor 1-like). Confirmed germline transmission. Cu...
Xla.ahremNXR X. laevis ahr.L Custom generated mutant made by NXR. Germ line transmission not yet confirmed. Contact NXR for detai...
Xtr.ahrem2NXR X. tropicalis ahr TALEN generated mutant line, made by the NXR. Germ line transmission confirmed. mutation: 7bp deleti...
Xtr.ahrem1NXR X. tropicalis ahr TALEN generated mutant line, made by the NXR. Germ line transmission confirmed. ,+2bp mutation: CCAT...
Xtr.thratmShiyb X. tropicalis thra This line was created using TALENS targeting exon 4 (the third coding exon) of the X. tropicalis thr...
Xla.kcptmFlc X. laevis kcp.L One-cell stage Xenopus Xla.Tg(Cardiac-actin:GFP)Mohun embryos were microinjected with 1 ng TALEN mRN...
Xtr.tp53em_del1/em_del2_Vlemx X. tropicalis tp53 Two types of F1 tp53 heterozygotes, each with a distinct variant of a deletion (em_del1/+ and em_del...
Xla.hps4m X. laevis hps4.L This periodic albino mutant of Xenopus laevis is a recessive mutant. Fukazawa et al 2020 showed that...
Xtr.tp53em_del2/+_Vlemx X. tropicalis tp53 Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deletio...
Xtr.tp53em_del1/+_Vlemx X. tropicalis tp53 Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deleti...
Xla.runx1em(GFP)EXRC X. laevis runx1.L CRISPR-Cas9 mediated insertion of IRES-GFP sequence into the 3'-UTR of runx1 gene,
Xtr.tbxt,tbxt.2emJcsm X. tropicalis tbxt Double talen-induced mutant line. Talen induced 2-bp deletion in exon 1 of tbxt and 7 bp deletion in...
Xtr.tbxt.2em2Jcsm X. tropicalis tbxt.2 Talen-induced mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ...
Xtr.tbxt.2em1Jcsm X. tropicalis tbxt.2 Talen-mediated mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ...
Xla.npffr1.1emEXRC X. laevis npffr1.1.L Crispr-Cas9 mutation in the npffr1.1 gene (neuropeptide FF receptor 1, gene 1 ).
Xtr.tbxtemJcsm X. tropicalis tbxt Talen-induced 2bp deletion in exon 1 of tbxt (T-box transcription factor T) gene. Mutation destroys ...
Xtr.oc90mZimml X. tropicalis oc90 Mutation affecting inner ear otoconia identified in the Mill Hill screen for ENU-induced mutations. ...
Xtr.ap3d1mZimml X. tropicalis ap3d1 Mutation affecting inner ear otoconia identified in the Mill Hill screen for ENU-induced mutations. ...
Xtr.atp7amZimml X. tropicalis atp7a A mutation affecting retinal epithelium identified in the Mill Hill screen for ENU-induced mutations...
Xtr.supt5hmZimml X. tropicalis supt5h Mutation affecting eye development and melanophore migration identified in the Mill Hill screen for ...
Xtr.petmZimml X. tropicalis unknown Homozygous mutants are completely paralyzed with no heartbeat.
Xtr.mlomZimml X. tropicalis unknown Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations. Map...
Xtr.unc45bmZimml X. tropicalis unc45b Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations.
Xtr.smad4mZimml X. tropicalis smad4 Mutation affecting haematopoiesis identified in a screen for ENU-induced mutations at Mill Hill. Pos...
Xtr.askmZimml X. tropicalis unknown Mutation affecting the formation of inner ear otoconia identified in the Mill Hill screen for ENU-in...
Xtr.bxemZimml X. tropicalis unknown Mutation affecting eye development identified in the Mill Hill screen for ENU-induced mutations.
Xtr.mammZimml X. tropicalis unknown Mutation affecting cardiac function identified in a screen for ENU-induced mutations at Mill Hill
Xtr.bunmZimml X. tropicalis unknown Mutation affecting the ear development identified in the Mill Hill screen for ENU-induced mutations.
Xtr.dstmZimml X. tropicalis unknown Mutation affecting the haematopoietic system identified in the Mill Hill screen for ENU-induced muta...
Xtr.tupmZimml X. tropicalis unknown Mutation affecting axial development identified in the Mill Hill screen of ENU-induced mutations.
Xtr.legmZimml X. tropicalis unknown Mutation affecting otoconia formation identified in the Mill Hill screen of ENU-induced mutations.
Xtr.runx2emHorb X. tropicalis runx2 CRISPR knockout of runx2 (runt related transcription factor 2). Contact NXR to inquire about availab...
Xtr.wwoxemHorb X. tropicalis wwox CRISPR knockout of wwox (WW domain containing oxidoreductase), a gene associated with esophageal can...
Xtr.amhem1NXR X. tropicalis amh CRISPR knockout of amh (anti-Mullerian hormone). Germline transmission confirmed. +8bp mutation in a...

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