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Results 301 - 350 of 495 results

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Line Name Species Mutated Gene(s) Description Availability
Xla.wdpcpemHorb X. laevis wdpcp.L CRISPR knockout of wdpcp (WD repeat containing planar cell polarity effector). Germ line transmissio...
Xla.olig2emHorb X. laevis olig2.L CRISPR knockout of olig2 (oligodendrocyte lineage transcription factor 2) in X. laevis. KOs both oli...
Xla.notch4emHorb X. laevis notch4.S TALEN knockout of notch4 in X. laevis. THIS LINE is no longer available from the NXR
Xla.mcidasemHorb X. laevis mcidas.L CRISPR knockout of mcidas (multiciliate differentiation and DNA synthesis associated cell cycle prot...
Xla.sox10emHorb X. laevis sox10.L CRISPR knockout of sox10 (SRY-box 10). Confirmed germline transmission in sox10.L (waiting for confi...
Xla.slc16a2emHorb X. laevis slc16a2.L CRISPR knockout of slc16a2 (solute carrier family 16, member 2 (thyroid hormone transporter)). Germ ...
Xla.mitfemHorb X. laevis mitf.L CRISPR knockout of mitf (melanocyte inducing transcription factor) Germ line transmission confirmed....
Xla.prph2emHorb X. laevis prph2.L CRISPR knockout of prph2 (peripherin 2 (retinal degeneration, slow)). Current mosaic founders, not t...
Xla.gfi1emHorb X. laevis gfi1.L CRISPR knockout of gfi1 (growth factor independent 1 transcription repressor ).Confirmed germline tr...
Xla.prickle1emHorb X. laevis prickle1.L CRISPR knockout of prickle1(prickle planar cell polarity protein 1). Confirmed germ line transmissio...
Xla.fxr1emHorb X. laevis fxr1.L CRISPR Knockout of fxr1(FMR1 autosomal homolog 1 ). Currently mosaic founders. Confirmed germline tr...
Xla.eya1emHorb X. laevis eya1.L CRISPR Knockout of eya1 (EYA transcriptional coactivator and phosphatase 1) .gRNAs target eya1.L and...
Xla.ppp2r2aemHorb X. laevis ppp2r2a.L CRISPR knockout of ppp2r2a (protein phosphatase 2 regulatory subunit B, alpha ). Current mosaic foun...
Xla.aqp1emHorb X. laevis aqp1.L CRISPR Knockout of aqp1.L and aqp1.S (Aquaporin1) Germline transmission confirmed. Mutation is a 1...
Xla.pkd2emHorb X. laevis pkd2.L CRISPR knockout of pkd2 (polycystin 2, transient receptor potential cation channel ). Confirmed germ...
Xla.pcntemHorb X. laevis pcnt.L CRISPR knockout of pcnt (pericentrin ). Confirmed germline transmission. Custom mutant generated by ...
Xla.pax7emHorb X. laevis pax7.L CRISPR knockout of pax7 (paired box ). Germ line transmission confirmed. Animals carry a 4bp 9 bp o...
Xla.pax3emHorb X. laevis pax3.L CRISPR knockout of pax3 (paired box 3). Germ line transmission confirmed. animals carry a 11bp delet...
Xla.olig3emHorb X. laevis olig3.S CRISPR knockout of olig3 (oligodendrocyte transcription factor 3) ( olig3.S in Xlaevis). Current mos...
Xla.slc45a1emNXR X. laevis slc45a1.L CRISPR knockout of Slc45a1 (solute carrier family 45 member 1 ). Screened for germline transmission....
Xtr.hpse2emHorb X. tropicalis hpse2 CRISPR knockout of hpse2 (heparanase 2 (inactive)). Confirmed germline transmission. Custom mutant g...
Xtr.glis3emHorb X. tropicalis glis3 CRISPR knockout of glis3 (GLIS family zinc finger 3). Confirmed germline transmission. Custom mutant...
Xtr.frzb,frzb2emHorb X. tropicalis frzb2 double CRISPR knockout of frzb (frizzled related protein ) and frzb2 (frizzled related protein 2). C...
Xtr.foxc2em1Horb X. tropicalis foxc2 CRISPR knockout of foxc2 (forkhead box C2). Confirmed germline transmission. Animals carry a 1 bp de...
Xtr.erfemHorb X. tropicalis erf CRISPR knockout of erf (ETS2 repressor factor). Confirmed germline transmission. Custom mutant gene...
Xtr.gdf1em1Horb X. tropicalis gdf1 CRISPR knockout of gdf1 (growth differentiation factor 1). Confirmed germline transmission. Custom ...
Xtr.ascl1emHorb X. tropicalis ascl1 CRISPR knockout of ascl1(achaete-scute family bHLH transcription factor 1). Confirmed germline trans...
Xtr.aif1lem1Horb X. tropicalis aif1l CRISPR knockout of aif1l (allograft inflammatory factor 1-like). Confirmed germline transmission. Cu...
Xtr.tlx3em1Horb X. tropicalis tlx3 CRISPR knockout of tlx3 (T cell leukemia homeobox 3). Confirmed germline transmission. Custom mutant...
Xtr.map3k13emHorb X. tropicalis map3k13 CRISPR knockout of map3k13 (mitogen-activated protein kinase kinase kinase 13). Confirmed germline t...
Xtr.rxrgemHorb X. tropicalis rxrg Description: CRISPR knockout of rxrg (retinoid X receptor gamma). Confirmed germline transmission. C...
Xtr.rxrbemHorb X. tropicalis rxrb CRISPR knockout of rxrb (retinoid X receptor beta). Confirmed germline transmission. Animals carry a...
Xtr.runx1em1Horb X. tropicalis runx1 CRISPR knockout of runx1(runt related transcription factor 1). Germ line transmission confirmed. Ani...
Xtr.prph2emHorb X. tropicalis prph2 CRISPR knockout of prph2 (peripherin 2 (retinal degeneration, slow)). Confirmed germ line transmissi...
Xtr.pou3f4emHorb X. tropicalis pou3f4 CRISPR knockout of pou3f4 (POU class 3 homeobox 4). Current mosaic founders, not tested for germline...
Xtr.olig4emHorb X. tropicalis olig4 CRISPR knockout of olig4 (oligodendrocyte transcription factor 4). Current mosaic founders, not test...
Xtr.olig2emHorb X. tropicalis olig2 CRISPR knockout of olig2 (oligodendrocyte lineage transcription factor 2) in X. tropicalis. Confirme...
Xtr.mitfemHorb X. tropicalis mitf CRISPR knockout of mitf (melanocyte inducing transcription factor). Current mosaic founders, not tes...
Xtr.lmnaemHorb X. tropicalis lmna CRISPR knockout of lmna (lamin A/C).Confirmed germline transmission. Mutants carry a 14 bp deletion ...
Xtr.insm2emHorb X. tropicalis insm2 CRISPR knockout of insm2 (insulinoma-associated 2). Confirmed germline transmission. Custom mutant g...
Xtr.hps6mGrngr X. tropicalis hps6 No Privacy (NOP) embryos have a 10-bp deletion in the hps6 gene (a region from 468 to 477 counted fr...
Xla.Tg(nkx2-5:GFP)Mohun X. laevis 8kb promoter of X. laevis NK2 homeobox 5 gene driving GFP
Xla.Tg(myl2:eGFP)Mohun X. laevis ~3kb myosin light chain (myl2, also known as xmlc2/mlc2) promoter driving enhanced GFP (eGFP) expres...
Xla.Tg(CMV:H3K9ac-mintbody)Ueno X. laevis CMV promoter driving expression of of the epigenetic sensor, H3K9ac-mintbody (modification-specific ...
Xla.Tg(tubb2b:ChIEF;Rno.elas:GFP)NXR X. laevis Xenopus neural (NBT/tubb2b) driving expression of blue light photoinducible channel rhodopsin (ChIEF...
Xla.Tg(ins:memGFP,cryga:mCherry)NXR X. laevis X. laevis 5kb insulin (ins) promoter driving membrane bound GFP (mGFP) expression; gamma crystallin ...
Xla.Tg(gata1:GFP)Mead X. laevis Xenopus GATA-1 (gata1) promoter and first intron, driving expression of GFP
Xla.Tg(tubb2b:GCaMP6s;Rno.elas:GFP)NXR X. laevis neural beta tubulin ( tubb2b) driving GCaMP6s, a genetically encoded calcium indicator created from ...
Xla.Tg(rho:eGFP-atp1a3)Baker X. laevis Xenopus rhodopsin (rho) promoter driving expression of eGFP tagged neuronal alpha-3 isoform of the N...
Xla.Tg(eef1a1:GFP;cryga:GFP)Krieg X. laevis Xenopus eukaryotic translation elongation factor 1 alpha 1 (eef1a1) promoter/enhancer driving GFP ex...

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