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Results 251 - 300 of 495 results

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Line Name Species Mutated Gene(s) Description Availability
Xtr.zbtb21emHorb X. tropicalis zbtb21 CRISPR knockout of zbtb21(zinc finger and BTB domain containing 21), Current mosaic founders, Not te...
Xtr.tspan8em1Horb X. tropicalis tspan8 CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 1of 3 tspan lines at th...
Xtr.bace1emHorb X. tropicalis bace1 CRISPR knockout of bace1 (beta-site APP-cleaving enzyme 1), Current mosaic founders, Not tested for ...
Xtr.junbemHorb X. tropicalis junb CRISPR knockout of junb (jun B proto-oncogene), Germ line transmission confirmed. Animals carry a 17...
Xtr.mapk10emHorb X. tropicalis mapk10 CRISPR knockout of mapk10 (mitogen-activated protein kinase 10), Germline transmission confirmed, Mu...
Xtr.icam5emHorb X. tropicalis icam5 CRISPR knockout of icam5 (intercellular adhesion molecule 5), Germ line transmission confirmed. Cust...
Xtr.sox3emHorb X. tropicalis sox3 CRISPR knockout of sox3 (SRY-box 3), Current mosaic founders, Not tested for germline transmission. ...
Xla.Tg(tuba1a:deup1-eGFP)NXR X. laevis Tubulin promoter driving expression of deup1 fused to eGFP labeling both deuterosomes and centrioles...
Xtr.ezh2emHorb X. tropicalis ezh2 CRISPR knockout of ezh2 (enhancer of zeste 2 polycomb repressive complex 2 subunit), Germ line trans...
Xtr.tbx2emHorb X. tropicalis tbx2 CRISPR knockout of tbx2 (T-box 2), Current mosaic founders, Not tested for germline transmission.
Xtr.zbtb14emHorb X. tropicalis zbtb14 CRISPR knockout of zbtb14 (zinc finger and BTB domain containing 14). Germ line transmission confirm...
Xtr.notch4emHorb X. tropicalis notch4 CRISPR knockout of notch4 in X. tropicalis. Confirmed germline transmission. Mutation characterized:...
Xtr.tlx3em2Horb X. tropicalis tlx3 CRISPR mutant line targeting tlx3 (T cell leukemia homeobox 3). Germ lIne transmission was confirmed...
Xtr.runx1t1emHorb X. tropicalis runx1t1 CRISPR knockout of runx1t1(RUNX1 partner transcriptional co-repressor 1) gene. Germ line transmissio...
Xla.hmgcremHorb X. laevis hmgcr.L CRISPR knockout of hmgcr (3-hydroxy-3-methylglutaryl-CoA reductase). Germline transmission confirmed...
Xtr.bhlhe22emHorb X. tropicalis bhlhe22 CRISPR knockout of bhlhee2 (basic helix-loop-helix family member e22), Current mosaic founders, Conf...
Xtr.kng1emHorb X. tropicalis kng1 CRISPR knockout of kng1 (kininogen 1), Germline transmission confirmed. Mutants carry a bp deletion ...
Xtr.fibinemHorb X. tropicalis fibin CRISPR knockout of fibin (fin bud initiation factor homolog), Confirmed germline transmission. Custo...
Xtr.tbx5emHorb X. tropicalis tbx5 CRISPR knockout of tbx5 (T-box 5 ), Confirmed germline transmission. Custom mutant generated by Horb...
Xtr.tyremNXR X. tropicalis tyr CRISPR knockout of tyr (tyrosinase), Confirmed germline transmission. Animal carry a 241bp insertion...
Xtr.raxmGrngr X. tropicalis rax This mutant line was generated in an ENU screen from the Grainger lab by TILLING (Targeting Induced ...
Xla.Tg(Xtr.hal2:eGFP;cryga:GFP3)Shi X. laevis This tg line carries a 4.4-kb HAL2 promoter in AcGFP1.1 vexctor , subcloned into the KpnI-AgeI diges...
Xtr.Tg(otx2:Gal4;cryga:eCFP)Zimml X. tropicalis Otx2 promoter driving Gal4 expression in eye region. Transgene is marked by eCFP expression in lens ...
Xtr.Tg(otx2:Gal4)Zimml X. tropicalis Otx2 promoter driving Gal4 expression.
Xtr.Tg(rax:Gal4;cryga:eCFP)Zimml X. tropicalis 2.2Kb retina and anterior neural fold homeobox (rax) promoter driving expression of Gal4. Transgene ...
Xtr.Tg(UAS:dkk1;cryga:RFP)Zimml X. tropicalis Gal4 responsive UAS promoter driving FLAG tagged dickkopf WNT signaling pathway inhibitor 1 (dkk1) e...
Xtr.Tg(UAS:Hsa.NOG-mGFP;actc1:RFP)Zimml X. tropicalis Gal4 responsive UAS element driving expression of a human noggin-GFP fusion protein.
Xtr.Tg(UAS:cer1;cryga:RFP)Zimml X. tropicalis Gal4 responsive UAS element driving expression of cerberus (cer1). Transgene marked by gamma-crystal...
Xtr.Tg(UAS:Hsa.HHIP;cryga:RFP)Zimml X. tropicalis Gal4 responsive UAS promoter drives human hedgehog interacting protein (HHIP). Linked to gamma cryst...
Xtr.Tg(pax6:PR-Gal4-VP16;cryga:eCFP)Zimml X. tropicalis Pax6 promoter driving RU486-inducible progesterone receptor (PR)/Gal4/VP16 transactivator. Linked to...
Xtr.Tg(myl2:Gal4;cryga:CFP)Zimml X. tropicalis Myosin light chain 2 (myl2) promoter driving Gal4 expression in heart.Linked to crystallin promoter ...
Xtr.Tg(myl2:GFP)Zimml X. tropicalis Cardiac myosin light chain 2 (myl2) promoter driving GFP expression.
Xtr.Tg(Dre.mnx1:GFP)Dorey X. tropicalis Zebrafish motor neuron and pancreas homeobox 1 gene (Dre.mnx1) promoter driving GFP expression.
Xtr.Tg(nectin2:Venus;cryga:RFP)Amaya X. tropicalis Xenopus nectin2 promoter drives Venus expression, and crystallin gamma A (cryga) driving RFP used as...
Xtr.Tg(vim:Venus;cryga:GFP)Amaya X. tropicalis Vimentin promoter driving Venus (a yellow FP), and gamma-crystalin (cryga) driving GFP as the marker...
Xtr.Tg(Hsa.UBC:Gal4-VP16;cryga:CFP)Amaya X. tropicalis Human Ubiquitin C (Hsa.UBC) promoter driving Gal4-VP16 fusion construct, with gamma-crystallin (cryg...
Xtr.Tg(hsp70:dnfgfr-Venus:cryga:RFP)Amaya X. tropicalis HSP70 heat shock inducible promoter driving dominant negative fgf receptor ((fgfr) with intracellula...
Xtr.Tg(UAS:mapt-Venus:Hsa.UBC:Gal4-VP16)Amaya X. tropicalis UAS driving mapt-Venus fusion expresssion to label mictrotubules. Ubiquitous Gal4-VP16 fusion expres...
Xtr.Tg(UAS:msn-mCherry;cryga:RFP)Amaya X. tropicalis UAS driving mCherry-Moesin with crystallin-RFP.
Xtr.Tg(Hsa.UBC:hist2h2be-mCherry)Amaya X. tropicalis Human Ubiquitin C (UBC) promoter driving expression of an H2B-mCherry fusion protein, ubiquitous nuc...
Xtr.Tg(Hsa.UBC:lyn-Venus)Amaya X. tropicalis Human Ubiquitin C (Hsa.UBC) promoter driving expression of a LYN proto-oncogene, Src family tyrosine...
Xtr.Tg(CMV:dTomato)Amaya X. tropicalis CMV promoter driving dTomato.
Xtr.Tg(cdknx:GFP)Papal X. tropicalis cyclin-dependent kinase inhibitor (cdknx, previously called Xic1) promoter driving GFP.
Xtr.Tg(Mmu.Tek:GFP)Amaya X. tropicalis Mouse Tie2 (Tek) promoter driving GFP expression.
Xtr.Tg(Xla.actc1:GFP)Mohun X. tropicalis 580 bp promoter of X. laevis cardiac actin gene driving expression of GFP.
Xtr.Tg(pax6:GFP)Amaya X. tropicalis 3.6kb Xenopus paired box 6 ( pax6) promoter driving GFP.
Xtr.Tg(tubb2b:Hsa.ALPP;cryga:dsRed)Amaya X. tropicalis Neural expression of human placental alkaline phosphatase (Hsa.ALPP) driven by N-beta-tubulin (tubb2...
Xtr.Tg(tubb2b:mapt-GFP)Amaya X. tropicalis 3481 bp N-beta-tubulin(tubb2b) promoter and 5'UTR driving expression of mapt-GFP fusion (tauGFP) in ...
Xtr.Tg(tubb2b:GFP)Amaya X. tropicalis Xenopus n-tubulin (tubb2b) promoter driving GFP.
Xla.wnt11emHorb X. laevis wnt11.L CRISPR knockout of wnt11 (Wnt family member 11), Confirmed germline transmission. Mutant line genera...

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