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Line Name Species Mutated Gene(s) Description Availability
Xtr.irx3emNXR X. tropicalis irx3 CRISPR knockout of irx3 (iroquois homeobox 3). Custom mutant line generated for the Veenstra Lab. Ge... NXR
Xtr.irx2emNXR X. tropicalis irx2 CRISPR knockout of irx2 (iroquois homeobox 2). Custom mutant line generated for the Veenstra Lab. Ge... NXR
Xtr.irx1emNXR X. tropicalis irx1 CRISPR knockout of irx1 (iroquois homeobox 1). Custom mutant line generated for the Veenstra Lab. Ge... NXR
Xla.il2rgemNXR X. laevis il2rg.L CRISPR knockout of il2rg (interleukin 2 receptor subunit gamma). Germ line transmission confirmed. ... NXR
Xtr.gtpbp2emNXR X. tropicalis gtpbp2 CRISPR knockout of gtpbp2 (GTP binding protein 2 ). Germ line transmission confirmed. Mutants carry ... NXR
Xtr.gfi1em2Horb X. tropicalis gfi1 CRISPR knockout of gfi1 (growth factor independent 1 transcription repressor). Germ line transmissio... NXR
Xtr.fuzemNXR X. tropicalis fuz CRAIPR knockout of fuz ( fuzzy planar cell polarity protein). Germ line transmission confirmed. Anim... NXR
Xtr.foxp3emNXR X. tropicalis foxp3 CRISPR knockout of foxp3 (forkhead box P3). Germ line transmission confirmed. Animals carry a net 1 ... NXR
Xtr.foxp2emNXR X. tropicalis foxp2 CRISPR knockout of foxp2 (forkhead box P2). Germ line transmission not yet confirmed. Mutation not ... NXR
Xtr.foxl2em1NXR X. tropicalis foxl2 CRISPR knockout of foxl2 (forkhead box L2). Germline transmission confirmed. Animals carry a 5 base ... NXR
Xtr.foxc2em2Horb X. tropicalis foxc2 CRISPR knockout of foxc2 (forkhead box C2). Confirmed germline transmission. Custom mutant generated... NXR
Xtr.foxd3emNXR X. tropicalis foxd3 CRISPR knockout of foxd3 (forkhead box D3). Germ line transmission confirmed. Animals carry a 5 base... NXR
Xtr.eya1em1NXR X. tropicalis eya1 CRISPR knockout of eya1 (EYA transcriptional coactivator and phosphatase 1). Germline transmission ... NXR
Xtr.eya1emNXR X. tropicalis eya1 CRISPR knockout of eya1 (EYA transcriptional coactivator and phosphatase 1). Germline transmission ...
Xla.dzip1emNXR X. laevis dzip1.L CRISPR knockout of dzip1 (Z interacting zinc finger protein 1). Germ line transmission not yet confi... NXR
Xla.xdm-wemNXR X. laevis dm-w.L CRISPR knock out of xdm-w (doublesex and mab3 related transcription factor W ). Germ Line transmissi...
Xla.dmrt1em3NXR X. laevis dmrt1.S CRISPR knockout of dmrt1.S (doublesex and mab-3 related transcription factor 1 ). Custom mutant line... NXR
Xla.dmrt1em2NXR X. laevis dmrt1.S CRISPR knockout of dmrt1.S (doublesex and mab-3 related transcription factor 1). Germline transmissi... NXR
Xla.dmrt1em1NXR X. laevis dmrt1.L CRISPR knockout of dmrt1.L (doublesex and mab-3 related transcription factor 1 ). Germ line transmis... NXR
Xtr.dmrt1emNXR X. tropicalis dmrt1 CRISPR knockout of dmrt1 (doublesex and mab-3 related transcription factor 1). Germ line transmissio... NXR
Xtr.cybbemHorb X. tropicalis cybb CRISPR knockout of cybb (cytochrome b-245, beta polypeptide). Germ line transmission not confirmed. ... NXR
Xtr.csnk1g2emNXR X. tropicalis csnk1g2 CRISPR knockout of csnk1g2 (casein kinase 1 gamma 2). Germ line transmission confirmed. Animals carr... NXR
Xla.csf3remNXR X. laevis csf3r.L CRISPR knockout of csf3r (colony stimulating factor 3 receptor). Germ line transmission confirmed. A... NXR
Xtr.cby1emNXR X. tropicalis cby1 TALEN knockout of cby1 (chibby homolog 1). Germ line transmission not confirmed. Mutation not charac... NXR
Xtr.celf3emNXR X. tropicalis celf3 CRISPR knock out of celf3 (CUGBP, Elav-like family member 3). Germ line transmission not yet confirm... NXR
Xla.ccdc78emNXR X. laevis ccdc78.S CRISPR knockout of ccdc78 (coiled-coil domain containing 78). Germ line transmission confirmed. Anim... NXR
Xtr.cacna1hem2NXR X. tropicalis cacna1h CRISPR knockout of cacna1h (calcium channel, voltage-dependent, T type, alpha 1H subunit). Germline ... NXR
Xtr.cacna1hem1NXR X. tropicalis cacna1h CRISPR knockout of cacna1h (calcium channel, voltage-dependent, T type, alpha 1H subunit). Germline ... NXR
Xtr.bicc1em1NXR X. tropicalis bicc1 CRISPR mutant of bicc1 (BicC family RNA binding protein 1). Germline transmission has been confirmed... NXR
Xtr.bcorem2Horb X. tropicalis bcor CRISPR knockout of bcor (BCL6 corepressor). Germline transmission confirmed. Animals carry a 1 base ... NXR
Xla.arntlemNXR X. laevis bmal1.L bmal1.S CRISPR knockout of arntl (arbon receptor nuclear translocator like). Germline transmission confirmed... NXR
Xla.arem2NXR X. laevis ar.L CRISPR mutation of ar (androgen receptor). Animals carry a 19 base pair deletion in ar.L Germline t... NXR
Xla.ar em1NXR X. laevis ar.L CRISPR mutation of ar (androgen receptor). Animals carry a 13 base pair deletion in ar.L Germline tr... NXR
Xtr.amhr2emNXR X. tropicalis amhr2 CRISPR knockout of amhr2 (anti-Mullerian hormone receptor type II ). Confirmed germline transmission... NXR
Xtr.amhem3NXR X. tropicalis amh CRISPR knockout lines targeting amh (anti-Mullerian hormone ) developed at the NXR. Confirmed germli... NXR
Xtr.amhem2NXR X. tropicalis amh CRISPR knockout line targeting amh (anti-Mullerian hormone). Confirmed germline transmission. Animal... NXR
Xtr.aif1lem2Horb X. tropicalis aif1l CRISPR knockout of aif1l (allograft inflammatory factor 1-like). Custom mutant generated by Horb Lab... NXR
Xla.ahremNXR X. laevis ahr.L Custom generated mutant made by NXR. Germ line transmission not yet confirmed. Contact NXR for detai...
Xtr.ahrem2NXR X. tropicalis ahr TALEN generated mutant line targeting ahr (aryl hydrocarbon receptor). Germ line transmission confir... NXR
Xtr.ahrem1NXR X. tropicalis ahr TALEN generated mutant line targeting ahr (aryl hydrocarbon receptor). Germ line transmission confir... NXR
Xla.adam13emNXR X. laevis CRISPR knockout of adam13 (ADAM metallopeptidase domain 13 ). Confirmed germline transmission. Anima... NXR
Xla.Tg(prrx1:CreER;CAGGs:lp-Cherry)Etnka X. laevis A stable double transgenic frog line that allows conditional labeling and tracing of limb connectiv...
Xla.Tg(rho:hsa.rhodel) X. laevis Line with a human mutant form of rhodopsin with a Glutamine to termination substitution, under the X...
Xla.Tg(rho:Hsa.rhosub_T4K) X. laevis Line with a human mutant form of rhodopsin with a Threonine to Lysine substitution, under the X.laev...
Xla.Tg(rho:Hsa.rhosub_T17M) X. laevis Line with a human mutant form of rhodopsin with a Threonine to Methionine substitution, under the X....
Xla.Tg(rho:hsa.rhosub_P23H) X. laevis Line with a human mutant form of rhodopsin with a Proline to Histidine substitution, which leads to ...
Xtr.thratmShiyb X. tropicalis thra This line was created using TALENS targeting exon 4 (the third coding exon) of the X. tropicalis thr...
Xla.kcptmFlc X. laevis kcp.L One-cell stage Xenopus Xla.Tg(Cardiac-actin:GFP)Mohun embryos were microinjected with 1 ng TALEN mRN...
Xtr.tp53em_del1/em_del2_Vlemx X. tropicalis tp53 Two types of F1 tp53 heterozygotes, each with a distinct variant of a deletion (em_del1/+ and em_del...
Xla.hps4m X. laevis hps4.L This periodic albino mutant of Xenopus laevis is a recessive mutant. Fukazawa et al 2020 showed that...

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