Search Lines and Strains
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| Line Name | Species | Mutated Gene(s) | Description | Availability |
| Xtr.slc2a7.tyr.hps6tmHUARC | X. tropicalis | hps6 slc2a7 tyr | triple knock out (3KO) line generated by crossing mutant lines with KO of tyr, hps6, and slc2a7 | |
| Xtr.thratm,thrbtmShiyb | X. tropicalis | thra thrb | Double knockout oth thyroid receptor alpha nd thyroid receptor bets. Produced in the lab of Yun-Bo S... | |
| Xtr.tyremOchi | X. tropicalis | tyr | An albino line with CRISPR/Cas9-targeted mutation in tyrosinase (tyr) gene, made by the Ochi Lab. Th... | NBRP |
| Xtr.tyremKtsz | X. tropicalis | tyr | An albino line with CRISPR/Cas9-targeted mutation in tyrosinase (tyr) gene, made by the Suzuki Lab. ... | NBRP |
| Xtr.hps6emOgino | X. tropicalis | hps6 | CRISPR/Cas9-mediated targeted mutation in hsp6, a gene resonsible for X. tropicalis no privacy (nop)... | NBRP |
| Xtr.bicc1em2NXR | X. tropicalis | bicc1 | CRISPR mutant of bicc1 (BicC family RNA binding protein 1). Germline transmission has been confirmed... | |
| Xtr.staremNXR | X. tropicalis | star | CRISPR knockout of STAR (steroidogenic acute regulatory protein). Germ line transmission not yet con... | |
| Xtr.foxb1em2Horb | X. tropicalis | foxb1 | CRISPR knockout of foxb1 (forkhead box B1 ), Current mosaic founders, germline transmission confirme... | |
| Xtr.acsl1emNXR | X. tropicalis | acsl1 | CRISPR knockout of acsl1 (acyl-CoA synthetase long chain family member 1). Germ line transmission co... | |
| Xtr.nagluem2NXR | X. tropicalis | naglu | CRISPR knockout of naglu (N-acetyl-alpha-glucosaminidase). Germ line transmission confirmed. Animals... | |
| Xtr.nagluem1NXR | X. tropicalis | naglu | CRISPR knockout of naglu (N-acetyl-alpha-glucosaminidase). Germ line transmission confirmed. Animals... | |
| Xtr.lamp2em2NXR | X. tropicalis | lamp2 | CRISPR knockout of lamp2 (lysosomal associated membrane protein 2 ). Germ line transmission confirme... | |
| Xtr.lamp2em1NXR | X. tropicalis | lamp2 | CRISPR knockout of lamp2 (lysosomal associated membrane protein 2 ). Germ line transmission confirme... | |
| Xtr.meis1emNXR | X. tropicalis | meis1 | CRISPR knockout of meis1 (meis homeobox 1). F0 growing, germline transmission not yet confirmed. | |
| Xtr.foxl2em2NXR | X. tropicalis | foxl2 | 2nd CRISPR knockout of foxl2 (forkhead box L2). Germline transmission confirmed. Mosaic founders and... | |
| Xtr.pou4f1em1NXR | X. tropicalis | pou4f1 | CRISPR knockout of pou4f1 (POU class 4 homeobox 1) in X. tropicalis. germ line transmission confirme... | |
| Xtr.foxp3em2NXR | X. tropicalis | foxp3 | CRISPR knockout of foxp3 (forkhead box P3). Germ line transmission confirmed. Animals carry a 17 bp ... | |
| Xtr.fermt2tm-/- Huzha | X. tropicalis | fermt2 | This is a CRISPR generated mutant giving rise to a 10bp deletion in the fermt2/kindlin2 gene. | |
| Xtr.apcMRCΔ1/+Vlemx | X. tropicalis | apc | F0 apc mosaics generated by apc TALENs injection, were outcrossed with WT X. tropicalis, and offspri... | |
| Xtr.Tg(mlc2:dnfosl1-eGFP)Qi | X. tropicalis | fosl1 | Fosl1 protein was mutated and truncated to generate 3 mutant polypeptides which then cloned into pc... | |
| Xtr.mtnr1aemNXR | X. tropicalis | mtnr1a | CRISPR knock out of mtnr1a (melatonin receptor 1A ) in X. tropicalis. germ line transmission confirm... | NXR |
| Xtr.six1em2NXR | X. tropicalis | six1 | CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc... | |
| Xtr.zmym4emNXR | X. tropicalis | zmym4 | CRISPR KO of zmym4 (zinc finger MYM-type containing 4) in X. tropicalis. Germline transmission confi... | |
| Xtr.zeb2emNXR | X. tropicalis | zeb2 | CRISPR KO of zeb2 (zinc finger E-box binding homeobox 2), a gene associated with Mowat-Wilson syndro... | |
| Xtr.ywhazemNXR | X. tropicalis | ywhaz | CRISPR KO of ywhaz (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). ge... | |
| Xtr.xbp1emNXR | X. tropicalis | xbp1 | CRISPR KO of xbp1 ( X-box binding protein 1 ) a gene assocaited with Major Affected Disorder in huma... | |
| Xla.baz1bemNXR | X. laevis | baz1b.L | TALENs knockout of baz1b (bromodomain adjacent to zinc finger domain 1B ) aka wstf,a gene associated... | |
| Xla.wnt11bemNXR | X. laevis | wnt11b.L | CRISPR knockout of wnt11b in X laevis. Germline transmission confirmed. F2 animals carry a 13bp del... | |
| Xtr.wnt11bemNXR | X. tropicalis | wnt11b | CRISPR knockout of wnt11b (wingless-type MMTV integration site family, member 11B ), Germ line tran... | |
| Xtr.wbp11emNXR | X. tropicalis | wbp11 | CRISPR knockout of wbp11 (WW domain binding protein 11). Germline transmission confirmed, F2s growin... | |
| Xtr.vwa2emNXR | X. tropicalis | vwa2 | CRISPR knock out of vwa2 (von Willebrand factor A domain containing 2 ). Germ line transmission conf... | |
| Xtr.vangl2emNXR | X. tropicalis | vangl2 | CRISPR knockout of vangl2 (VANGL planar cell polarity protein 2 ), a gene associated with neural tub... | |
| Xtr.tspan8em3Horb | X. tropicalis | tspan8 | CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 3rd of 3 tspan lines at... | |
| Xtr.tspan8em2Horb | X. tropicalis | tspan8 | CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 2nd of 3 tspan lines at... | |
| Xla.trilemNXR | X. laevis | tril.L | CRISPR knockout of tril (LR4 interactor with leucine-rich repeats). Co-injected for both L and S. Ge... | |
| Xla.thrbem3NXR | X. laevis | thrb.L | Double CRISPR mutant line of thrb (thyroid hormone receptor, beta ) with animals carrying a 8bp dele... | |
| Xla.thrbem2NXR | X. laevis | thrb.S | CRISPR knockout of thrb.S thyroid hormone receptor, beta S homolog). germline transmission confirmed... | |
| Xla.thrbem1NXR | X. laevis | thrb.L | CRISPR knockout of thrb.L thyroid hormone receptor, beta L homolog). germline transmission confirmed... | |
| Xtr.tdrd1emNXR | X. tropicalis | tdrd1 | CRISPR knockout of tdrd1 (tudor domain containing 1). Germline transmission not yet confirmed. growi... | |
| Xtr.srd5a3emNXR | X. tropicalis | srd5a3 | CRISPR knockout of srd5a3 (steroid 5 alpha-reductase 3), Germ line transmission confirmed. F1 growin... | |
| Xtr.srd5a2emNXR | X. tropicalis | srd5a2 | CRISPR knockout of srd5a2 (steroid 5 alpha-reductase 2), Confirmed germ line transmission. animals c... | |
| Xla.sobpemNXR | X. tropicalis | sobp | CRISPR knockout of sobp (sine oculis binding protein homolog ), a gene associated with MRAMS, an in... | |
| Xtr.snai2emNXR | X. tropicalis | snai2 | CRISPR knockout of snai2 (snail family zinc finger 2) in X. tropicalis. Germ line transmission confi... | |
| Xtr.snai1emNXR | X. tropicalis | snai1 | CRISPR knockout of snai1 (snail family zinc finger 1) in X. tropicalis. germline transmission confir... | |
| Xtr.six1em1NXR | X. tropicalis | six1 | CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc... | |
| Xtr.sf3b4emNXR | X. tropicalis | sf3b4 | CRISPR knockout of sf3b4 (splicing factor 3b subunit 4) in X tropicalis. sf3b4 is a gene associated ... | |
| Xla.slc45a2em2NXR | X. laevis | slc45a2.L | CRISPR knockout of slc45a2 (solute carrier family 45 member 2 ). Screened for germline transmission.... | |
| Xla.slc45a2emNXR | X. laevis | slc45a2.L | ||
| Xtr.foxn1emHuarc | X. tropicalis | foxn1 | An athymic line with TALEN-mediated targeted mutation in foxn1 gene, made by the Yaoita Lab. Absence... | NBRP |
| Xtr.rxraemNXR | X. tropicalis | rxra | CRISPR knockout of rxra (retinoid X receptor alpha ). Germ line transmission confirmed. Animals carr... |
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