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XB-PHENO-25789

Xla Wt + Hsa.RAF1L603P LoF, Wong S et al. (2023)

Experiment + Assay: Xla Wt + Hsa.RAF1L603P LoF + NF10.5 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection   raf1 (Xla)
 NF stage 3 (4-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 10.5  
Anatomical Phenotypes: decreased size of the mesoderm
Expression Phenotypes (1):
decreased amount tbxt.L expression in marginal zone
Source: Fig. 2D r1c4
Article: XB-ART-59687, PubMed