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XB-PHENO-25781

Xla Wt + fzd3 MO, Chuykin I et al. (2021)

Experiment + Assay: Xla Wt + fzd3 MO + NF16 (immunohistochemistry)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection fzd3 MO1 fzd3 (Xla)
 NF stage 5 (16-cell) dorsal animal hemisphere blastomere
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 16 Vangl2 Ab4
Anatomical Phenotypes: abnormal establishment of cell polarity
Expression Phenotypes (1):
decreased amount vangl2.L expression in plasma membrane
Source: Fig.1.C,C'
Article: XB-ART-58654, PubMed