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XB-PHENO-25603

Xla Wt + cyp26a1 + aldh1a2 MO, Gur M et al. (2022)

Experiment + Assay: Xla Wt + cyp26a1 + aldh1a2 MO + NF32 (whole-mount microscopy)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection cyp26a1.L cyp26a1.L
 NF stage 1 zygote
morpholino injection aldh1a2 MO2 aldh1a2 (Xla)
 NF stage 1 zygote
Conditions:
Assay Type Assay Stages Antibody
whole-mount microscopy NF stage 32  
Anatomical Phenotypes: abnormal development of eye , decreased size of the head
Human Disease Associations: microcephaly
Source: Fig.5.B,E
Article: XB-ART-58916, PubMed