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XB-PHENO-24453

Xla Wt + six1 + mcrs1, Neilson KM et al. (2020)

Experiment + Assay: Xla Wt + six1 + mcrs1 + NF13-18 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection six1.L six1.L
 NF stage 4 (8-cell) animal blastomere
mRNA injection mcrs1 (Xla) mcrs1 (Xla)
 NF stage 4 (8-cell) animal blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 13 to NF stage 18  
Expression Phenotypes (2):
decreased amount sox11.L expression in preplacodal ectoderm
increased amount sox11.L expression in preplacodal ectoderm
Source: Fig. 5 A
Article: XB-ART-57914, PubMed