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XB-PHENO-23751

Xla Wt + chrd MO + nog MO, Rankin SA et al. (2011)

Experiment + Assay: Xla Wt + chrd MO + nog MO + NF11 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection chrd.1 MO1 chrd.S
chrd.L
 NF stage 3 (4-cell) blastomere
morpholino injection chrd.1 MO2 chrd.L
chrd.S
 NF stage 3 (4-cell) blastomere
morpholino injection nog MO1 nog.S
nog.L
 NF stage 3 (4-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 11  
Expression Phenotypes (10):
decreased amount chrd.1.L expression in dorsal endoderm
decreased amount hhex.L expression in dorsal endoderm
increased amount ventx1.2.L expression in animal cap
mislocalised ventx1.2.L expression in animal cap
increased amount ventx1.2.L expression in dorsal endoderm
mislocalised ventx1.2.L expression in dorsal endoderm
increased amount ventx2.2.L expression in animal cap
mislocalised ventx2.2.L expression in animal cap
increased amount ventx2.2.L expression in dorsal endoderm
mislocalised ventx2.2.L expression in dorsal endoderm
Source: fig.8
Article: XB-ART-42631, PubMed