Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-PHENO-23018

Xtr Wt + Mmu.osr1-GR + osr1 MO + osr2 MO, Rankin SA et al. (2012)

Experiment + Assay: Xtr Wt + Mmu.osr1-GR + osr1 MO + osr2 MO + NF35/36 (in situ hybridization)
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection osr1 MO1 osr1
 NF stage 4 (8-cell) blastomere
mRNA injection Tg(Mmu.osr1-GR) osr1
 NF stage 4 (8-cell) blastomere D2
morpholino injection osr2 MO1 osr2
 NF stage 4 (8-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 35 and 36  
Anatomical Phenotypes: absent lung bud
Expression Phenotypes (1):
decreased amount nkx2-1 expression in lung bud
Source: fig.2.b,e,e^1
Article: XB-ART-45616, PubMed