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XB-PHENO-22973

Xla Wt + Mmu.fgfr1del-Mmu.fkbp1adel + wnt2 MO + B/B Homodimerizer, Rankin SA et al. (2015)

Experiment + Assay: Xla Wt + Mmu.fgfr1del-Mmu.fkbp1adel + wnt2 MO + B/B Homodimerizer + NF42 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection wnt2 MO1 wnt2.L
wnt2.S
 NF stage 3 (4-cell) blastomere
mRNA injection Tg(Mmu.fgfr1del-Mmu.fkbp1adel) fgfr1.L
fgfr1.S
 NF stage 4 (8-cell) blastomere
chemical B/B Homodimerizer
NF stage 25 whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 42  
Expression Phenotypes (1):
decreased amount sftpc.L expression in lung bud
Source: fig.10.o
Article: XB-ART-49397, PubMed