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XB-PHENO-22604

Xla Wt + Dre.lbx1 + myod1, Martin BL and Harland RM (2006)

Experiment + Assay: Xla Wt + Dre.lbx1 + myod1 + NF29/30 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(Dre.lbx1) lbx1.L
lbx1.S
 NF stage 2 (2-cell) right blastomere
mRNA injection myod1.S myod1.L
myod1.S
 NF stage 2 (2-cell) right blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 29 and 30  
Anatomical Phenotypes: increased size of the hypaxial muscle
Expression Phenotypes (2):
decreased amount pax3.S expression in hypaxial muscle
decreased amount pax3.S expression in neural tube
Source: Fig.9 j k l
Article: XB-ART-962, PubMed