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XB-PHENO-20947

Xla Wt + aldh1a2 + sdr16c5 + retinol, Belyaeva OV et al. (2012)

Experiment + Assay: Xla Wt + aldh1a2 + sdr16c5 + retinol + NF32-32 (morphology)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection sdr16c5.L sdr16c5.L
sdr16c5.S
 NF stage 3 (4-cell) blastomere
mRNA injection aldh1a2.L aldh1a2.L
aldh1a2.S
 NF stage 3 (4-cell) blastomere
chemical retinol
NF stage 8 whole organism
Conditions:
Assay Type Assay Stages Antibody
morphology NF stage 32 to NF stage 32  
Anatomical Phenotypes: abnormally anteriorly mislocalised eye, abnormally incomplete structure of head, absent eye, decreased length of anterior-posterior axis, fused eyes
Source: fig.5.a, b
Article: XB-ART-44754, PubMed