Xla Wt + sipa1l3 MO has 6 phenotype(s)
Images Sources Experiment + Assay Phenotypes Human Diseases
fig.S5.a, b

Rothe M et al. (2017)
Xla Wt + sipa1l3 MO

NF42 (cell death detection assay)
Anatomical Phenotype
abnormally increased number of apoptotic cell
increased apoptosis in embryo
fig.S2.a

Rothe M et al. (2017)
Xla Wt + sipa1l3 MO

NF42 (in situ hybridization)
Anatomical Phenotype
abnormal development of eye
abnormal development of retinal layer
abnormal retinal ganglion cell layer morphology
abnormally localised retinal ganglion cell layer
abnormally localised retinal inner nuclear layer
Expression Phenotype
decreased amount rho.L expression in photoreceptor layer
increased amount pax6.L expression in amacrine cell
increased amount pax6.L expression in retinal ganglion cell layer
increased amount pou4f1.L expression in retinal ganglion cell layer
increased amount vsx1.L expression in retinal inner nuclear layer
mislocalised pax6.L expression in photoreceptor layer
mislocalised pax6.L expression in retinal inner nuclear layer
mislocalised rho.L expression in retinal inner nuclear layer
mislocalised vsx1.L expression in retinal ganglion cell layer
fig.S3.a

Rothe M et al. (2017)
Xla Wt + sipa1l3 MO

NF42 (real time PCR)
Expression Phenotype
increased amount celf1.L expression in eye
fig.S2.b

Rothe M et al. (2017)
Xla Wt + sipa1l3 MO

NF42 (RT-PCR)
Expression Phenotype
decreased amount rho.L expression in eye
increased amount pax6.L expression in eye
increased amount pou4f1.L expression in eye
increased amount vsx1.L expression in eye
fig.7.a, b, c

Rothe M et al. (2017)
Xla Wt + sipa1l3 MO

NF42 (whole-mount microscopy)
Anatomical Phenotype
abnormal development of eye
abnormal eye morphology
decreased size of the eye
fig.7.h, i, j

Rothe M et al. (2017)
Xla Wt + sipa1l3 MO

NF42 (whole-mount microscopy)
Anatomical Phenotype
abnormal development of eye
abnormal eye morphology
decreased size of the eye