Fig. 2A

Lee H et al. (2020)

Xla Wt + gpx3 MO

NF28 (RT-PCR)

Expression Phenotype
decreased amount fgf8.L expression in embryo absent wnt3a.L expression in embryo decreased amount notch1.L expression in embryo

Fig. 3 ABCD

Yang J et al. (2020)

Xla Wt + xbp1 MO

NF10 (in situ hybridization)

Expression Phenotype

decreased amount fgf8.L expression in mesoderm
decreased amount fgf3.L expression in marginal zone
decreased amount fgf3.L expression in mesoderm
decreased amount foxa2.L expression in endoderm
decreased amount gata4.L expression in endomesoderm
decreased amount gata6.L expression in endomesoderm
decreased amount myod1.L expression in mesoderm
decreased amount sox2.L expression in neuroectoderm
decreased amount tbxt.L expression in marginal zone
decreased amount tgif2.L expression in ectoderm
decreased amount tgif2.L expression in mesoderm
decreased amount wnt6.L expression in ectoderm
increased amount hhex.L expression in endomesoderm
increased amount mixer.L expression in endoderm
increased amount sox3.L expression in neuroectoderm

Fig.4.D

Ossipova O et al. (2020)

Xla Wt + pnhd-FLAG + animal cap explant

NF10.5-11 (RT-PCR)

Expression Phenotype
increased amount fgf8.L expression in animal cap increased amount cdx4.L expression in the animal cap increased amount hoxd1.L expression in the animal cap increased amount tbxt.S expression in the animal cap increased amount wnt8a.L expression in the animal cap

Fig.4.B,C

Ossipova O et al. (2020)

Xla Wt + pnhd-FLAG + animal cap explant

NF11 (RNA-Seq)

Expression Phenotype

increased amount fgf8.L expression in animal cap
increased amount cdx1.L expression in the animal cap
increased amount cdx4.L expression in the animal cap
increased amount esr-5.L expression in the animal cap
increased amount flrt3.L expression in the animal cap
increased amount hoxd1.L expression in the animal cap
increased amount msgn1.L expression in the animal cap
increased amount myf5.L expression in the animal cap
increased amount tbxt.S expression in the animal cap
increased amount vegt.L expression in the animal cap
increased amount wnt8a.L expression in the animal cap
decreased amount ccne2.S expression in the animal cap
decreased amount foxi4.2.L expression in the animal cap
decreased amount nedd9.L expression in the animal cap
decreased amount nedd9.S expression in the animal cap
decreased amount xepsin.L expression in the animal cap

Fig.4.D

Ossipova O et al. (2020)

Xla Wt + pnhd + animal cap explant

NF12 (RT-PCR)

Expression Phenotype
increased amount fgf8.L expression in animal cap increased amount cdx4.L expression in the animal cap increased amount hoxd1.S expression in the animal cap increased amount tbxt.S expression in the animal cap increased amount wnt8a.L expression in the animal cap

Fig. 7 C

Sullivan CH et al. (2019)

Xla Wt + irx1

NF 16-NF 18 (in situ hybridization)

Expression Phenotype
decreased amount fgf8.L expression in preplacodal ectoderm

Fig 7 ADGJM (c1)

Deimling SJ and Drysdale TA (2011)

Xla Wt + Retinoic acid

NF18-20 (in situ hybridization)

Expression Phenotype
decreased amount fgf8.L expression in anterior placodal area increased amount fgf8.L expression in anterior neural tube increased amount fgf8.L expression in posterior neural tube

Fig. 7 CFILO

Deimling SJ and Drysdale TA (2011)

Xla Wt + retinol

NF18-20 (in situ hybridization)

Expression Phenotype

absent fgf8.L expression in anterior neural tube
absent fgf8.L expression in presumptive midbrain-hindbrain boundary
decreased amount fgf8.L expression in adenohypophyseal placode
decreased amount fgf8.L expression in anterior placodal area
increased amount fgf8.L expression in posterior neural tube
absent fgf4.L expression in presumptive paraxial mesoderm
decreased amount spry2.L expression in cardiac mesoderm
increased amount spry2.L expression in neural tube

fig.5.c

Mir A et al. (2007)

Xla Wt + Activin + animal cap explant

NF11 (RT-PCR)

Expression Phenotype
increased amount fgf8.L expression in animal cap increased amount tbxt.L expression in animal cap

fig.5.c

Mir A et al. (2007)

Xla Wt + foxi1 MO + Activin + animal cap explant

NF11 (RT-PCR)

Expression Phenotype
increased amount fgf8.L expression in animal cap