XB-PHENO-25913

Cervino AS et al. (2023)

Xla WT + ssbp2 MO

NF26 (in situ hybridization)

Expression Phenotype
decreased amount pax8.L expression in pronephric duct decreased amount pax8.L expression in pronephric kidney decreased amount pax8.L expression in pronephric mesenchyme

Fig. 5 e, j, o

Cervino AS et al. (2023)

Xla WT + ssbp2 MO

NF32 (in situ hybridization)

Anatomical Phenotype
abnormal pronephric tubule morphology decreased size of the distal tubule decreased size of the pronephric tubule decreased size of the proximal tubule

Expression Phenotype
decreased amount clcnkb.L expression in pronephric tubule decreased amount pax2.L expression in pronephric tubule decreased amount pax2.L expression in proximal tubule decreased amount slc5a1.L expression in proximal tubule

Fig S5. e j o p

Cervino AS et al. (2023)

Xla WT + ssbp2 MO

NF32 (in situ hybridization)

Anatomical Phenotype
abnormal development of pronephric duct abnormal development of pronephric kidney abnormal pronephric tubule morphology decreased size of the pronephric tubule

Expression Phenotype
decreased amount hoxb7.L expression in pronephric kidney decreased amount lhx1.L expression in proximal tubule decreased amount pax8.L expression in proximal tubule

Fig. 3 e j m m' n o

Cervino AS et al. (2023)

Xla WT + ssbp2 MO

NF35/36 (in situ hybridization)

Anatomical Phenotype
abnormal glomus morphology

Expression Phenotype
decreased amount nphs1.L expression in glomus decreased amount wt1.L expression in glomus