Xla + asxl3 MO has 8 phenotype(s)

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Sources

Experiment + Assay

Phenotypes

Human Diseases

Fig. 1 C

Lichtig H et al. (2020)

Xla + asxl3 MO

NF16 (RT-PCR)

Expression Phenotype
decreased amount egr2.L expression in embryo decreased amount tubb2b.L expression in embryo

Fig. 3 B lanes 4,5

Lichtig H et al. (2020)

Xla + asxl3 MO

NF16 (RT-PCR)

Expression Phenotype
decreased amount egr2.L expression in embryo decreased amount hoxb1.L expression in embryo decreased amount hoxb3.L expression in embryo

Fig. 4 C lane 3

Lichtig H et al. (2020)

Xla + asxl3 MO

NF16 (RT-PCR)

Expression Phenotype
absent ag1.L expression in embryo absent egr2.L expression in embryo absent foxd1.L expression in embryo absent foxd3.L expression in embryo absent foxg1.L expression in embryo absent tubb2b.L expression in embryo decreased amount hoxb3.L expression in embryo decreased amount ncam1.L expression in embryo decreased amount snai1.L expression in embryo

Fig 1 A

Lichtig H et al. (2020)

Xla + asxl3 MO

NF17-19 (whole-mount microscopy)

Anatomical Phenotype
abnormal anterior neural tube morphology abnormal neural plate morphology abnormal neural tube closure

Fig. 2 D 2rc2

Lichtig H et al. (2020)

Xla + asxl3 MO

NF17-19 (whole-mount microscopy)

Expression Phenotype
decreased amount twist1.L expression in cranial neural crest decreased amount twist1.L expression in neural tube

Fig. 1 B r1c2

Lichtig H et al. (2020)

Xla + asxl3 MO

NF18 (in situ hybridization)

Anatomical Phenotype
abnormal anterior neural tube morphology abnormal neural tube closure

Expression Phenotype
decreased amount tubb2b.L expression in neural tube decreased amount tubb2b.L expression in Rohon-Beard neuron decreased amount tubb2b.L expression in trigeminal placode

Fig. 1B r2c2

Lichtig H et al. (2020)

Xla + asxl3 MO

NF18 (in situ hybridization)

Expression Phenotype
absent egr2.L expression in hindbrain absent egr2.L expression in rhombomere R3 absent egr2.L expression in rhombomere R5 decreased amount egr2.L expression in cranial neural crest

Fig. 5. A r1/2 c3/4

Lichtig H et al. (2020)

Xla + asxl3 MO

NF37/38 (whole-mount microscopy)

Anatomical Phenotype
abnormal anatomical axis abnormal anterior-posterior axis, curved lateral abnormal head morphology abnormal trunk region arrested axis elongation