Images

Sources

Experiment + Assay

Phenotypes

Human Diseases

Fig. 5 C r2

Mishra-Gorur K et al. (2023)

Xtr Wt + traf7 CRISPR

NF28-29/30 (in situ hybridization)

Expression Phenotype
absent pitx2 expression in lateral plate mesoderm absent pitx2 expression in left side

Fig. 5. C r3

Mishra-Gorur K et al. (2023)

Xtr Wt + traf7 CRISPR

NF28-29/30 (in situ hybridization)

Expression Phenotype
mislocalised pitx2 expression in lateral plate mesoderm mislocalised pitx2 expression in right side

Fig. 2. O

Mishra-Gorur K et al. (2023)

Xtr wt + traf7 MO

NF16-18 (in situ hybridization)

Expression Phenotype
absent sox10 expression in neural crest absent twist1 expression in neural crest

Fig. 5 B r2c1-3; B''

Mishra-Gorur K et al. (2023)

Xtr wt + traf7 MO

NF17 (immunohistochemistry)

Anatomical Phenotype
abnormally decreased number of cilium in the left-right organizer

Expression Phenotype
decreased amount arl13b expression in cilium