Fig. 5 c2, c3

Mishra-Gorur K et al. (2023)

Xtr Wt + traf7 CRISPR

NF17 (scanning electron microscopy)

Anatomical Phenotype
abnormal cilium morphology abnormal multiciliated cell abnormally decreased number of cilium in the left-right organizer abnormally decreased number of cilium in the multiciliated cell

Fig. 5 C r2

Mishra-Gorur K et al. (2023)

Xtr Wt + traf7 CRISPR

NF28-29/30 (in situ hybridization)

Expression Phenotype
absent pitx2 expression in lateral plate mesoderm absent pitx2 expression in left side

Fig. 5. C r3

Mishra-Gorur K et al. (2023)

Xtr Wt + traf7 CRISPR

NF28-29/30 (in situ hybridization)

Expression Phenotype
mislocalised pitx2 expression in lateral plate mesoderm mislocalised pitx2 expression in right side

Fig S5 G H

Mishra-Gorur K et al. (2023)

Xtr Wt + traf7 CRISPR

NF28-29/30 (whole-mount microscopy)

Anatomical Phenotype
abnormal tail morphology edematous brain edematous head edematous heart

Fig. 3. K M

Mishra-Gorur K et al. (2023)

Xtr Wt + traf7 CRISPR

NF37/38-39 (whole-mount microscopy)

Anatomical Phenotype
abnormal head morphology abnormal tail morphology edematous head

Fig. 2 N Movie S4

Mishra-Gorur K et al. (2023)

Xtr Wt + traf7 CRISPR

NF42 (whole-mount microscopy)

Anatomical Phenotype
abnormal heart looping abnormal heart morphology

Movie S4.

Mishra-Gorur K et al. (2023)

Xtr Wt + traf7 CRISPR

NF42 (whole-mount microscopy)

Anatomical Phenotype
abnormal head morphology abnormal heart looping

Fig. S5 L L'

Mishra-Gorur K et al. (2023)

Xtr Wt + traf7 CRISPR

NF42 (whole-mount microscopy)

Anatomical Phenotype
abnormal chondrocranium morphology abnormal head morphology increased size of the pronephric kidney

Fig. 6. A

Mishra-Gorur K et al. (2023)

Xtr Wt + traf7 CRISPR

NF44 (transmission electron microscopy)

Anatomical Phenotype
abnormal cilium morphology abnormal cilium morphology in the pronephric kidney

Movie S13.

Mishra-Gorur K et al. (2023)

Xtr Wt + traf7 CRISPR

NF46-48 (swept field confocal) + IHC

Anatomical Phenotype
abnormal cerebrospinal fluid abnormal cilium motility edematous brain