Fig. 9 A.iii iv, C

Nguyen LT et al. (2023)

Xla.Tg(mbp:GFP-NTR) + MTZ

NF55 (immunohistochemistry)

Expression Phenotype
decreased amount mbp.L expression in optic nerve

multiple sclerosis

Fig. 9 D

Nguyen LT et al. (2023)

Xla.Tg(mbp:GFP-NTR) + UNC2025

NF55 (immunohistochemistry)

Anatomical Phenotype
abnormally decreased number of myelin accumulating cell

Expression Phenotype
decreased amount mbp.L expression in optic nerve

multiple sclerosis

Fig. 2. C-M

Edwards-Faret G et al. (2021)

Xla Wt + spinal cord amputation

NF50 + 2 dpt ( immunohistochemistry)

Expression Phenotype

increased amount mbp.L expression in spinal cord
increased amount aldh1l1.L expression in spinal cord
increased amount ascl1.L expression in spinal cord
increased amount dcx.L expression in spinal cord
increased amount nes.L expression in spinal cord
increased amount neurod1.L expression in spinal cord
increased amount neurog2.L expression in spinal cord
increased amount neurog3.L expression in spinal cord
increased amount sox10.L expression in spinal cord
increased amount sox2.L expression in spinal cord
increased amount vim.L expression in spinal cord

Fig. 6 C-M

Edwards-Faret G et al. (2021)

Xla Wt + spinal cord amputation

NF50 + 6 dpt (immunohistochemistry)

Expression Phenotype

decreased amount mbp.L expression in spinal cord
decreased amount sox10.L expression in spinal cord
increased amount aldh1l1.L expression in spinal cord
increased amount ascl1.L expression in spinal cord
increased amount dcx.L expression in spinal cord
increased amount nes.L expression in spinal cord
increased amount neurog2.L expression in spinal cord
increased amount neurog3.L expression in spinal cord
increased amount sox2.L expression in spinal cord
increased amount vim.L expression in spinal cord

Fig S1.

Yaoita Y and Nakajima K (2018)

Xtr Wt + TALEN thra

NF61 (RT-PCR)

Expression Phenotype
decreased amount mbp expression in brain decreased amount atp1a2 expression in brain decreased amount atp1b3 expression in brain decreased amount nefl expression in brain decreased amount nefm expression in brain decreased amount syt2 expression in brain

Fig. S1.

Yaoita Y and Nakajima K (2018)

Xtr Wt + TALEN thrb

NF61 (RT-PCR)

Expression Phenotype
increased amount mbp expression in brain increased amount atp1a2 expression in brain increased amount atp1b3 expression in brain increased amount nefl expression in brain increased amount nefm expression in brain increased amount syt2 expression in brain