Fig. 4. Expression pattern of Raldh3 during Xenopus development. (A) Raldh3 expression as detected by whole-mount in situ hybridization of whole embryos (stage 10.25-31) or dissected neural retinas, without lens and pigmented epithelium (stage 59). cf, choroid fissure. Scale bar: 350 μm. (B) Raldh3 expression in transverse sections of stage 33 embryos after whole-mount in situ hybridization. From left to right, sections show expression at progressively posterior levels. op, olfactory placode; os, optic stalk. (C) Comparison of Pax2, Raldh3 and Vax2 expression in the optic cup in transversal sections of stage 33 embryos after whole-mount in situ hybridization. (D) Double in situ hybridizations of Rx1 with Raldh2, Shh or FGF8 on mid- to late neurula embryos shown from anterior view. The inset shows a double in situ hybridization of Rx1 with FGF8 on an early neurula embryo.
Image published in: Lupo G et al. (2005)
Copyright © 2005. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| fgf8 | AIGF, FGF-8, fgf-8b, fgf8a, fgf8b, MGC79739, Xfgf-8, Xfgf8 | Xenopus | Throughout NF stage 17 | anterior neural fold |
| pax2 | LOC108697493, pax-2, pax2-a, pax2-b, XPax-2, XPax2 | Xenopus | Throughout NF stage 33 and 34 | retina ventral |
| shh | hedgehog, vhh-1, X-SHH, Xhh, xshh | Xenopus | Throughout neurula stage | notochord floor plate |
| rax | rax-a, rax-b, rax1, rx, rx-1, rx1, rx1a, Rx2A, Xrax, Xrx1, Xrx1A | Xenopus | Throughout NF stage 14 | eye primordium optic vesicle |
| vax2 | dres93, vax2-a, vax2-b, vax3, xvax2 | Xenopus | Throughout NF stage 33 and 34 | retina optic stalk ventral |
| aldh1a2 | raldh-2, raldh2, XRaldh2 | Xenopus | Throughout NF stage 17 | optic vesicle eye primordium anterior neural fold |
| aldh1a3 | raldh3 | Xenopus | Throughout NF stage 10.25 | blastopore lip upper blastopore lip |
| aldh1a3 | raldh3 | Xenopus | Throughout NF stage 11 | dorsal |
| aldh1a3 | raldh3 | Xenopus | Throughout NF stage 23 | ventral optic vesicle midbrain-hindbrain boundary dorsal otic placode |
| aldh1a3 | raldh3 | Xenopus | Throughout NF stage 33 and 34 | ventral optic vesicle olfactory placode retina |
| aldh1a3 | raldh3 | Xenopus | Sometime during NF stage 59 to NF stage 60 | ventral eye retina |
| fgf8 | AIGF, FGF-8, fgf-8b, fgf8a, fgf8b, MGC79739, Xfgf-8, Xfgf8 | Xenopus | Sometime during NF stage 17 to NF stage 18 | anterior neural fold neuroectoderm midbrain-hindbrain boundary neural tube |
| rax | rax-a, rax-b, rax1, rx, rx-1, rx1, rx1a, Rx2A, Xrax, Xrx1, Xrx1A | Xenopus | Throughout NF stage 17 | retina optic vesicle eye primordium |
| aldh1a3 | raldh3 | Xenopus | Throughout NF stage 12.5 | dorsal chordal neural plate |
| aldh1a3 | raldh3 | Xenopus | Throughout NF stage 31 | retina optic vesicle midbrain-hindbrain boundary otic vesicle otic placode cement gland ventral olfactory placode |
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