Summary Literature (212)

Xenbase Articles :
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Subthreshold changes of voltage-dependent activation of the K(V)7.2 channel in neonatal epilepsy., Hunter J,Maljevic S,Shankar A,Siegel A,Weissman B,Holt P,Olson L,Lerche H,Escayg A, Neurobiol Dis. October 1, 2006; 24(1):1095-953X.

Introduction to nucleocytoplasmic transport: molecules and mechanisms., Peters R, Methods Mol Biol. January 1, 2006; 322:1940-6029.

Dominant-negative effects of human P/Q-type Ca2+ channel mutations associated with episodic ataxia type 2., Jeng CJ,Chen YT,Chen YT,Chen YW,Chen YW,Tang CY, Am J Physiol Cell Physiol. April 1, 2006; 290(4):1522-1563.

A truncated Kv1.1 protein in the brain of the megencephaly mouse: expression and interaction., Persson AS,Klement G,Almgren M,Sahlholm K,Nilsson J,Petersson S,Arhem P,Schalling M,Lavebratt C, BMC Neurosci. November 23, 2005; 6:1471-2202.

Reduced U snRNP assembly causes motor axon degeneration in an animal model for spinal muscular atrophy., Winkler C,Eggert C,Gradl D,Meister G,Giegerich M,Wedlich D,Laggerbauer B,Fischer U, Genes Dev. October 1, 2005; 19(19):1549-5477.

A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization., Hurst RS,Hajós M,Raggenbass M,Wall TM,Higdon NR,Lawson JA,Rutherford-Root KL,Berkenpas MB,Hoffmann WE,Piotrowski DW,Groppi VE,Allaman G,Ogier R,Bertrand S,Bertrand D,Arneric SP, J Neurosci. April 27, 2005; 25(17):1529-2401.

Simple sequence in brain and nervous system specific proteins., Huntley MA,Mahmood S,Golding GB, Genome. April 1, 2005; 48(2):0831-2796.

Effect of galantamine on the human alpha7 neuronal nicotinic acetylcholine receptor, the Torpedo nicotinic acetylcholine receptor and spontaneous cholinergic synaptic activity., Texidó L,Ros E,Martín-Satué M,López S,Aleu J,Marsal J,Solsona C, Br J Pharmacol. July 1, 2005; 145(5):1476-5381.

Induction of ectopic olfactory structures and bone morphogenetic protein inhibition by Rossy, a group XII secreted phospholipase A2., Muñoz-Sanjuán I,Brivanlou AH, Mol Cell Biol. May 1, 2005; 25(9):1098-5549.

Functional polymorphisms in the human beta4 subunit of nicotinic acetylcholine receptors., Liang Y,Salas R,Marubio L,Bercovich D,De Biasi M,Beaudet AL,Dani JA, Neurogenetics. February 1, 2005; 6(1):1364-6745.

Transgenic animal models of tauopathies., Lee VM,Kenyon TK,Trojanowski JQ, Biochim Biophys Acta. January 3, 2005; 1739(2-3):0006-3002.

Familial hemiplegic migraine type 1 mutations K1336E, W1684R, and V1696I alter Cav2.1 Ca2+ channel gating: evidence for beta-subunit isoform-specific effects., Müllner C,Broos LA,van den Maagdenberg AM,Striessnig J, J Biol Chem. December 10, 2004; 279(50):1083-351X.

Regulation and function of small heat shock protein genes during amphibian development., Heikkila JJ, J Cell Biochem. November 1, 2004; 93(4):0730-2312.

Modification of Kv2.1 K+ currents by the silent Kv10 subunits., Vega-Saenz de Miera EC, Brain Res Mol Brain Res. April 7, 2004; 123(1-2):0169-328X.

Modulation of DMT1 activity by redox compounds., Marciani P,Trotti D,Hediger MA,Monticelli G, J Membr Biol. January 15, 2004; 197(2):1432-1424.

Microtransplantation of functional receptors and channels from the Alzheimer's brain to frog oocytes., Miledi R,Dueñas Z,Martinez-Torres A,Kawas CH,Eusebi F, Proc Natl Acad Sci U S A. February 10, 2004; 101(6):1091-6490.

Mutations linked to generalized epilepsy in humans reduce GABA(A) receptor current., Macdonald RL,Bianchi MT,Bianch MT,Feng H, Exp Neurol. November 1, 2003; 184 Suppl 1:0014-4886.

Molecular motions of the outer ring of charge of the sodium channel: do they couple to slow inactivation?, Xiong W,Li RA,Tian Y,Tomaselli GF, J Gen Physiol. September 1, 2003; 122(3):1540-7748.

Functional characterization of a glutamate/aspartate transporter from the mosquito Aedes aegypti., Umesh A,Cohen BN,Ross LS,Gill SS, J Exp Biol. July 1, 2003; 206(Pt 13):1477-9145.

Down-regulation of GABA-transporter function by hippocampal translation products: its possible role in epilepsy., Fueta Y,Vasilets LA,Takeda K,Kawamura M,Schwarz W, Neuroscience. January 1, 2003; 118(2):1873-7544.

Amyloid beta(1-42) peptide alters the gating of human and mouse alpha-bungarotoxin-sensitive nicotinic receptors., Grassi F,Palma E,Tonini R,Amici M,Ballivet M,Eusebi F, J Physiol. February 15, 2003; 547(Pt 1):0022-3751.

Functional and biochemical analysis of a sodium channel beta1 subunit mutation responsible for generalized epilepsy with febrile seizures plus type 1., Meadows LS,Malhotra J,Loukas A,Thyagarajan V,Kazen-Gillespie KA,Koopman MC,Kriegler S,Isom LL,Ragsdale DS, J Neurosci. December 15, 2002; 22(24):1529-2401.

Abnormal Tau phosphorylation of the Alzheimer-type also occurs during mitosis., Delobel P,Flament S,Hamdane M,Mailliot C,Sambo AV,Bégard S,Sergeant N,Delacourte A,Vilain JP,Buée L, J Neurochem. October 1, 2002; 83(2):1471-4159.

Identification and molecular cloning of Xenopus laevis SP22, a protein associated with fertilization in mammals., Monetti C,Vigetti D,Gornati R,Prati M,Klinefelter GR,Bernardini G, Comp Biochem Physiol B Biochem Mol Biol. August 1, 2002; 132(4):1096-4959.

Two different mechanisms of disinhibition produced by GABAA receptor mutations linked to epilepsy in humans., Bianchi MT,Song L,Zhang H,Macdonald RL, J Neurosci. July 1, 2002; 22(13):1529-2401.

Modelling Alzheimer-specific abnormal Tau phosphorylation independently of GSK3beta and PKA kinase activities., Delobel P,Flament S,Hamdane M,Delacourte A,Vilain JP,Buée L, FEBS Lett. April 10, 2002; 516(1-3):1873-3468.

Expression of the gene encoding the beta-amyloid precursor protein APP in Xenopus laevis., van den Hurk WH,Bloemen M,Martens GJ, Brain Res Mol Brain Res. December 16, 2001; 97(1):0169-328X.

[Cellular mechanism of seizure discharge and its normalization by a herbal mixture prescription "saikokeishito-ka-shakuyaku" (SK)]., Sugaya A, Yakugaku Zasshi. May 1, 2001; 121(5):1347-5231.

SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter., Trotti D,Rolfs A,Danbolt NC,Brown RH,Hediger MA, Nat Neurosci. May 1, 1999; 2(5):1546-1726.

Analysis of 3-(4-hydroxy, 2-Methoxybenzylidene)anabaseine selectivity and activity at human and rat alpha-7 nicotinic receptors., Meyer EM,Kuryatov A,Gerzanich V,Lindstrom J,Papke RL, J Pharmacol Exp Ther. December 1, 1998; 287(3):1521-0103.

Notch in vertebrates., Robey E, Curr Opin Genet Dev. August 1, 1997; 7(4):0959-437X.

Expanded CTG triplet blocks from the myotonic dystrophy gene create the strongest known natural nucleosome positioning elements., Wang YH,Griffith J, Genomics. January 20, 1995; 25(2):1089-8646.

Molecular cloning and chromosomal localization of the key subunit of the human N-methyl-D-aspartate receptor., Karp SJ,Masu M,Eki T,Ozawa K,Nakanishi S, J Biol Chem. February 15, 1993; 268(5):1083-351X.

Infection of a poikilothermic cell line (XL-2) with eastern equine encephalitis and western equine encephalitis viruses., Morier L,Cantelar N,Soler M, J Med Virol. March 1, 1987; 21(3):0146-6615.

Multiple sclerosis cerebrospinal fluid produces myelin lesions in tadpole optic nerves., Tabira T,Webster HD,Wray SH, N Engl J Med. September 16, 1976; 295(12):1533-4406.

Na,K-ATPase mutations in familial hemiplegic migraine lead to functional inactivation., Koenderink JB,Zifarelli G,Qiu LY,Schwarz W,De Pont JJ,Bamberg E,Friedrich T, Biochim Biophys Acta. May 15, 2005; 1669(1):0006-3002.

Functional analysis of a novel potassium channel (KCNA1) mutation in hereditary myokymia., Chen H,von Hehn C,Kaczmarek LK,Ment LR,Pober BR,Hisama FM, Neurogenetics. April 1, 2007; 8(2):1364-6745.

NIPA1(SPG6), the basis for autosomal dominant form of hereditary spastic paraplegia, encodes a functional Mg2+ transporter., Goytain A,Hines RM,El-Husseini A,Quamme GA, J Biol Chem. March 16, 2007; 282(11):1083-351X.

Paracrine and autocrine mechanisms of apelin signaling govern embryonic and tumor angiogenesis., Kälin RE,Kretz MP,Meyer AM,Kispert A,Heppner FL,Brändli AW, Dev Biol. May 15, 2007; 305(2):1095-564X.

Chimeric molecules to target proteins for ubiquitination and degradation., Sakamoto KM, Methods Enzymol. January 1, 2005; 399:1557-7988.

Rat's trick to escape Alzheimer's disease., Shen L,Ji HF, J Biomol Struct Dyn. December 1, 2007; 25(3):1538-0254.

Neutralization of a negative charge in the S1-S2 region of the KV7.2 (KCNQ2) channel affects voltage-dependent activation in neonatal epilepsy., Wuttke TV,Penzien J,Fauler M,Seebohm G,Lehmann-Horn F,Lerche H,Jurkat-Rott K, J Physiol. January 15, 2008; 586(2):0022-3751.

Reduced levels of survival motor neuron protein leads to aberrant motoneuron growth in a Xenopus model of muscular atrophy., Ymlahi-Ouazzani Q,J Bronchain O,Paillard E,Ballagny C,Chesneau A,Jadaud A,Mazabraud A,Pollet N, Neurogenetics. February 1, 2010; 11(1):1364-6745.

A functional null mutation of SCN1B in a patient with Dravet syndrome., Patino GA,Claes LR,Lopez-Santiago LF,Slat EA,Dondeti RS,Chen C,O'Malley HA,Gray CB,Miyazaki H,Nukina N,Oyama F,De Jonghe P,Isom LL, J Neurosci. August 26, 2009; 29(34):1529-2401.

A non-enzymatic function of 17beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival., Rauschenberger K,Schöler K,Sass JO,Sauer S,Djuric Z,Rumig C,Wolf NI,Okun JG,Kölker S,Schwarz H,Fischer C,Grziwa B,Runz H,Nümann A,Shafqat N,Kavanagh KL,Hämmerling G,Wanders RJ,Shield JP,Wendel U,Stern D,Nawroth P,Hoffmann GF,Bartram CR,Arnold B,Bierhaus A,Oppermann U,Steinbeisser H,Zschocke J, EMBO Mol Med. February 1, 2010; 2(2):1757-4684.

Enhancement of GABA(A)-current run-down in the hippocampus occurs at the first spontaneous seizure in a model of temporal lobe epilepsy., Mazzuferi M,Palma E,Martinello K,Maiolino F,Roseti C,Fucile S,Fabene PF,Schio F,Pellitteri M,Sperk G,Miledi R,Eusebi F,Simonato M, Proc Natl Acad Sci U S A. February 16, 2010; 107(7):1091-6490.

An epilepsy/dyskinesia-associated mutation enhances BK channel activation by potentiating Ca2+ sensing., Yang J,Krishnamoorthy G,Saxena A,Zhang G,Shi J,Yang H,Delaloye K,Sept D,Cui J, Neuron. June 24, 2010; 66(6):0896-6273.

Neurological disease mutations compromise a C-terminal ion pathway in the Na(+)/K(+)-ATPase., Poulsen H,Khandelia H,Morth JP,Bublitz M,Mouritsen OG,Egebjerg J,Nissen P, Nature. September 2, 2010; 467(7311):0143-5221.

Animal models for autosomal dominant frontal lobe epilepsy: on the origin of seizures., Steinlein OK, Expert Rev Neurother. December 1, 2010; 10(12):1744-8360.

RG3487, a novel nicotinic α7 receptor partial agonist, improves cognition and sensorimotor gating in rodents., Wallace TL,Callahan PM,Tehim A,Bertrand D,Tombaugh G,Wang S,Xie W,Rowe WB,Ong V,Graham E,Terry AV,Rodefer JS,Herbert B,Murray M,Porter R,Santarelli L,Lowe DA, J Pharmacol Exp Ther. January 1, 2011; 336(1):1521-0103.

Episodic ataxia type 1 mutations affect fast inactivation of K+ channels by a reduction in either subunit surface expression or affinity for inactivation domain., Imbrici P,D'Adamo MC,Grottesi A,Biscarini A,Pessia M, Am J Physiol Cell Physiol. June 1, 2011; 300(6):1522-1563.

A neuroprotective role for polyamines in a Xenopus tadpole model of epilepsy., Bell MR,Belarde JA,Johnson HF,Aizenman CD, Nat Neurosci. April 1, 2011; 14(4):1546-1726.

ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair., Cosentino C,Grieco D,Costanzo V, EMBO J. February 2, 2011; 30(3):0261-4189.

Allosteric modulation of related ligand-gated ion channels synergistically induces long-term potentiation in the hippocampus and enhances cognition., Johnstone TB,Gu Z,Yoshimura RF,Villegier AS,Hogenkamp DJ,Whittemore ER,Huang JC,Tran MB,Belluzzi JD,Yakel JL,Gee KW, J Pharmacol Exp Ther. March 1, 2011; 336(3):1521-0103.

Stomatin-deficient cryohydrocytosis results from mutations in SLC2A1: a novel form of GLUT1 deficiency syndrome., Flatt JF,Guizouarn H,Burton NM,Borgese F,Tomlinson RJ,Forsyth RJ,Baldwin SA,Levinson BE,Quittet P,Aguilar-Martinez P,Delaunay J,Stewart GW,Bruce LJ, Blood. November 10, 2011; 118(19):1528-0020.

Kcna1-mutant rats dominantly display myokymia, neuromyotonia and spontaneous epileptic seizures., Ishida S,Sakamoto Y,Nishio T,Baulac S,Kuwamura M,Ohno Y,Takizawa A,Kaneko S,Serikawa T,Mashimo T, Dev Biol. January 30, 2012; 1435:0012-1606.

GlialCAM, a protein defective in a leukodystrophy, serves as a ClC-2 Cl(-) channel auxiliary subunit., Jeworutzki E,López-Hernández T,Capdevila-Nortes X,Sirisi S,Bengtsson L,Montolio M,Zifarelli G,Arnedo T,Müller CS,Schulte U,Nunes V,Martínez A,Jentsch TJ,Gasull X,Pusch M,Estévez R, Neuron. March 8, 2012; 73(5):0896-6273.

Isthmin inhibits glioma growth through antiangiogenesis in vivo., Yuan B,Xian R,Ma J,Chen Y,Chen Y,Lin C,Song Y, J Neurooncol. September 1, 2012; 109(2):1573-7373.

Live imaging of targeted cell ablation in Xenopus: a new model to study demyelination and repair., Kaya F,Mannioui A,Chesneau A,Sekizar S,Maillard E,Ballagny C,Houel-Renault L,Dupasquier D,Bronchain O,Holtzmann I,Desmazieres A,Thomas JL,Demeneix BA,Brophy PJ,Zalc B,Mazabraud A, J Neurosci. September 12, 2012; 32(37):1529-2401.

Functional and structural effects of amyloid-β aggregate on Xenopus laevis oocytes., Parodi J,Ochoa-de la Paz L,Miledi R,Martínez-Torres A, Mol Cells. October 1, 2012; 34(4):0219-1032.

Imbalance of Hsp70 family variants fosters tau accumulation., Jinwal UK,Akoury E,Abisambra JF,O'Leary JC,Thompson AD,Blair LJ,Jin Y,Bacon J,Nordhues BA,Cockman M,Zhang J,Li P,Zhang B,Borysov S,Uversky VN,Biernat J,Mandelkow E,Gestwicki JE,Zweckstetter M,Dickey CA, FASEB J. April 1, 2013; 27(4):1530-6860.

Early infantile epileptic encephalopathy associated with a high voltage gated calcium channelopathy., Edvardson S,Oz S,Abulhijaa FA,Taher FB,Shaag A,Zenvirt S,Dascal N,Elpeleg O, J Med Genet. February 1, 2013; 50(2):1468-6244.

Identification and characterization of a small-molecule inhibitor of Wnt signaling in glioblastoma cells., De Robertis A,Valensin S,Rossi M,Tunici P,Verani M,De Rosa A,Giordano C,Varrone M,Nencini A,Pratelli C,Benicchi T,Bakker A,Hill J,Sangthongpitag K,Pendharkar V,Liu B,Ng FM,Then SW,Jing Tai S,Cheong SM,He X,Caricasole A,Salerno M, Mol Cancer Ther. July 1, 2013; 12(7):1538-8514.

Ciliogenesis and cerebrospinal fluid flow in the developing Xenopus brain are regulated by foxj1., Hagenlocher C,Walentek P,M Ller C,Thumberger T,Feistel K, Cilia. April 29, 2013; 2(1):2046-2530.

GRIN2B mutations in West syndrome and intellectual disability with focal epilepsy., Lemke JR,Hendrickx R,Geider K,Laube B,Schwake M,Harvey RJ,James VM,Pepler A,Steiner I,Hörtnagel K,Neidhardt J,Ruf S,Wolff M,Bartholdi D,Caraballo R,Platzer K,Suls A,De Jonghe P,Biskup S,Weckhuysen S, Ann Neurol. January 1, 2014; 75(1):1531-8249.

KCNJ10 mutations display differential sensitivity to heteromerisation with KCNJ16., Parrock S,Hussain S,Issler N,Differ AM,Lench N,Guarino S,Oosterveld MJ,Keijzer-Veen M,Brilstra E,van Wieringen H,Konijnenberg AY,Amin-Rasip S,Dumitriu S,Klootwijk E,Knoers N,Bockenhauer D,Kleta R,Zdebik AA, Nephron Physiol. January 1, 2013; 123(3-4):1660-2137.

Congenital ataxia and hemiplegic migraine with cerebral edema associated with a novel gain of function mutation in the calcium channel CACNA1A., García Segarra N,Gautschi I,Mittaz-Crettol L,Kallay Zetchi C,Al-Qusairi L,Van Bemmelen MX,Maeder P,Bonafé L,Schild L,Roulet-Perez E, J Neurol Sci. July 15, 2014; 342(1-2):1878-5883.

The molecular mechanism of intestinal levodopa absorption and its possible implications for the treatment of Parkinson's disease., Camargo SM,Vuille-dit-Bille RN,Mariotta L,Ramadan T,Huggel K,Singer D,Götze O,Verrey F, J Pharmacol Exp Ther. October 1, 2014; 351(1):1521-0103.

The prostaglandin EP1 receptor potentiates kainate receptor activation via a protein kinase C pathway and exacerbates status epilepticus., Rojas A,Gueorguieva P,Lelutiu N,Quan Y,Shaw R,Dingledine R, Neurobiol Dis. October 1, 2014; 70:1095-953X.

Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy., Simons C,Rash LD,Crawford J,Ma L,Cristofori-Armstrong B,Miller D,Ru K,Baillie GJ,Alanay Y,Jacquinet A,Debray FG,Verloes A,Shen J,Yesil G,Guler S,Yuksel A,Cleary JG,Grimmond SM,McGaughran J,King GF,Gabbett MT,Taft RJ, Nat Genet. January 1, 2015; 47(1):1546-1718.

Effect of the CALHM1 G330D and R154H human variants on the control of cytosolic Ca2+ and Aβ levels., Vingtdeux V,Tanis JE,Chandakkar P,Zhao H,Dreses-Werringloer U,Campagne F,Foskett JK,Marambaud P, PLoS One. November 6, 2014; 9(11):1932-6203.

Properties, regulation, pharmacology, and functions of the K₂p channel, TRESK., Enyedi P,Czirják G, Pflugers Arch. May 1, 2015; 467(5):1432-2013.

Moving gating charges through the gating pore in a Kv channel voltage sensor., Lacroix JJ,Hyde HC,Campos FV,Bezanilla F, Proc Natl Acad Sci U S A. May 13, 2014; 111(19):1091-6490.

R-(+) and S-(-) isomers of cotinine augment cholinergic responses in vitro and in vivo., Terry AV,Callahan PM,Bertrand D, J Pharmacol Exp Ther. February 1, 2015; 352(2):1521-0103.

A functional correlate of severity in alternating hemiplegia of childhood., Li M,Jazayeri D,Corry B,McSweeney KM,Heinzen EL,Goldstein DB,Petrou S, Neurobiol Dis. May 1, 2015; 77:1095-953X.

A recurrent de novo mutation in KCNC1 causes progressive myoclonus epilepsy., Muona M,Berkovic SF,Dibbens LM,Oliver KL,Maljevic S,Bayly MA,Joensuu T,Canafoglia L,Franceschetti S,Michelucci R,Markkinen S,Heron SE,Hildebrand MS,Andermann E,Andermann F,Gambardella A,Tinuper P,Licchetta L,Scheffer IE,Criscuolo C,Filla A,Ferlazzo E,Ahmad J,Ahmad A,Baykan B,Said E,Topcu M,Riguzzi P,King MD,Ozkara C,Andrade DM,Engelsen BA,Crespel A,Lindenau M,Lohmann E,Saletti V,Massano J,Privitera M,Espay AJ,Kauffmann B,Duchowny M,Møller RS,Straussberg R,Afawi Z,Ben-Zeev B,Samocha KE,Daly MJ,Petrou S,Lerche H,Palotie A,Lehesjoki AE, Nat Genet. January 1, 2015; 47(1):1546-1718.

Nav1.1 modulation by a novel triazole compound attenuates epileptic seizures in rodents., Gilchrist J,Dutton S,Diaz-Bustamante M,McPherson A,Olivares N,Kalia J,Escayg A,Bosmans F, ACS Chem Biol. May 16, 2014; 9(5):1554-8937.

Mutating a conserved proline residue within the trimerization domain modifies Na+ binding to excitatory amino acid transporters and associated conformational changes., Hotzy J,Schneider N,Kovermann P,Fahlke C, J Biol Chem. December 20, 2013; 288(51):1083-351X.

Remyelination by Resident Oligodendrocyte Precursor Cells in a Xenopus laevis Inducible Model of Demyelination., Sekizar S,Mannioui A,Azoyan L,Colin C,Thomas JL,Du Pasquier D,Mallat M,Zalc B, Dev Neurosci. January 1, 2015; 37(3):1421-9859.

Genetically induced dysfunctions of Kir2.1 channels: implications for short QT3 syndrome and autism-epilepsy phenotype., Ambrosini E,Sicca F,Brignone MS,D'Adamo MC,Napolitano C,Servettini I,Moro F,Ruan Y,Guglielmi L,Pieroni S,Servillo G,Lanciotti A,Valvo G,Catacuzzeno L,Franciolini F,Molinari P,Marchese M,Grottesi A,Guerrini R,Santorelli FM,Priori S,Pessia M, Hum Mol Genet. September 15, 2014; 23(18):1460-2083.

GABAA currents are decreased by IL-1β in epileptogenic tissue of patients with temporal lobe epilepsy: implications for ictogenesis., Roseti C,van Vliet EA,Cifelli P,Ruffolo G,Baayen JC,Di Castro MA,Bertollini C,Limatola C,Aronica E,Vezzani A,Palma E, Neurobiol Dis. October 1, 2015; 82:1095-953X.

The N-methyl-D-aspartate receptor's neglected subunit - GluN1 matters under normal and hyperbaric conditions., Bliznyuk A,Aviner B,Golan H,Hollmann M,Grossman Y, Eur J Neurosci. October 1, 2015; 42(8):1460-9568.

Huntingtin is required for ciliogenesis and neurogenesis during early Xenopus development., Haremaki T,Deglincerti A,Brivanlou AH, Dev Biol. December 15, 2015; 408(2):1095-564X.

Human slack potassium channel mutations increase positive cooperativity between individual channels., Kim GE,Kronengold J,Barcia G,Quraishi IH,Martin HC,Blair E,Taylor JC,Dulac O,Colleaux L,Nabbout R,Kaczmarek LK, Cell Rep. December 11, 2014; 9(5):2211-1247.

A Disease Mutation Causing Episodic Ataxia Type I in the S1 Links Directly to the Voltage Sensor and the Selectivity Filter in Kv Channels., Petitjean D,Kalstrup T,Zhao J,Blunck R, J Neurosci. September 2, 2015; 35(35):1529-2401.

Analyzing and Modeling the Kinetics of Amyloid Beta Pores Associated with Alzheimer's Disease Pathology., Ullah G,Demuro A,Parker I,Pearson JE, PLoS One. September 4, 2015; 10(9):1932-6203.

Amyloid pore-channel hypothesis: effect of ethanol on aggregation state using frog oocytes for an Alzheimer's disease study., Parodi J,Ormeño D,Ochoa-de la Paz LD, BMB Rep. January 1, 2015; 48(1):1976-670X.

Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes., Lemke JR,Lal D,Reinthaler EM,Steiner I,Nothnagel M,Alber M,Geider K,Laube B,Schwake M,Finsterwalder K,Franke A,Schilhabel M,Jähn JA,Muhle H,Boor R,Van Paesschen W,Caraballo R,Fejerman N,Weckhuysen S,De Jonghe P,Larsen J,Møller RS,Hjalgrim H,Addis L,Tang S,Hughes E,Pal DK,Veri K,Vaher U,Talvik T,Dimova P,Guerrero López R,Serratosa JM,Linnankivi T,Lehesjoki AE,Ruf S,Wolff M,Buerki S,Wohlrab G,Kroell J,Datta AN,Fiedler B,Kurlemann G,Kluger G,Hahn A,Haberlandt DE,Kutzer C,Sperner J,Becker F,Weber YG,Feucht M,Steinböck H,Neophythou B,Ronen GM,Gruber-Sedlmayr U,Geldner J,Harvey RJ,Hoffmann P,Herms S,Altmüller J,Toliat MR,Thiele H,Nürnberg P,Wilhelm C,Stephani U,Helbig I,Lerche H,Zimprich F,Neubauer BA,Biskup S,von Spiczak S, Nat Genet. September 1, 2013; 45(9):1546-1718.

Xenopus laevis as a Model to Identify Translation Impairment., de Broucker A,Semaille P,Cailliau K,Martoriati A,Comptdaer T,Bodart JF,Destée A,Chartier-Harlin MC, J Vis Exp. September 27, 2015; (103):1940-087X.

Channelopathies: ion channel defects linked to heritable clinical disorders., Felix R, J Med Genet. October 1, 2000; 37(10):1468-6244.

Distinctive effects of nicotinic receptor intracellular-loop mutations associated with nocturnal frontal lobe epilepsy., Weltzin MM,Lindstrom JM,Lukas RJ,Whiteaker P, Neuropharmacology. March 1, 2016; 102:1873-7064.

Polyunsaturated fatty acids are potent openers of human M-channels expressed in Xenopus laevis oocytes., Liin SI,Karlsson U,Bentzen BH,Schmitt N,Elinder F, Acta Physiol (Oxf). September 1, 2016; 218(1):1748-1716.

Acetylcholine receptors from human muscle as pharmacological targets for ALS therapy., Palma E,Reyes-Ruiz JM,Lopergolo D,Roseti C,Bertollini C,Ruffolo G,Cifelli P,Onesti E,Limatola C,Miledi R,Inghilleri M, Proc Natl Acad Sci U S A. March 15, 2016; 113(11):1091-6490.

The search for NKCC1-selective drugs for the treatment of epilepsy: Structure-function relationship of bumetanide and various bumetanide derivatives in inhibiting the human cation-chloride cotransporter NKCC1A., Lykke K,Töllner K,Feit PW,Erker T,MacAulay N,Löscher W, Epilepsy Behav. June 1, 2016; 59:1525-5069.

Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy., Sicca F,Ambrosini E,Marchese M,Sforna L,Servettini I,Valvo G,Brignone MS,Lanciotti A,Moro F,Grottesi A,Catacuzzeno L,Baldini S,Hasan S,D'Adamo MC,Franciolini F,Molinari P,Santorelli FM,Pessia M, Sci Rep. September 28, 2016; 6:2045-2322.

The Enigma of the Dichotomic Pressure Response of GluN1-4a/b Splice Variants of NMDA Receptor: Experimental and Statistical Analyses., Bliznyuk A,Gradwohl G,Hollmann M,Grossman Y, Front Mol Neurosci. February 15, 2016; 9:1662-5099.

Mutation Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Reduces Low-Sensitivity α4β2, and Increases α5α4β2, Nicotinic Receptor Surface Expression., Nichols WA,Henderson BJ,Marotta CB,Yu CY,Richards C,Dougherty DA,Lester HA,Cohen BN, PLoS One. January 1, 2016; 11(6):1932-6203.

Novel KCNQ3 Mutation in a Large Family with Benign Familial Neonatal Epilepsy: A Rare Cause of Neonatal Seizures., Maljevic S,Vejzovic S,Bernhard MK,Bertsche A,Weise S,Döcker M,Lerche H,Lemke JR,Merkenschlager A,Syrbe S, Mol Syndromol. September 1, 2016; 7(4):1661-8769.

Association between Single-Nucleotide Polymorphisms of the hOGG1,NEIL1,APEX1, FEN1,LIG1, and LIG3 Genes and Alzheimer's Disease Risk., Kwiatkowski D,Czarny P,Toma M,Korycinska A,Sowinska K,Galecki P,Bachurska A,Bielecka-Kowalska A,Szemraj J,Maes M,Sliwinski T, Neuropsychobiology. January 1, 2016; 73(2):1423-0224.

Mutations in GABRB3: From febrile seizures to epileptic encephalopathies., Møller RS,Wuttke TV,Helbig I,Marini C,Johannesen KM,Brilstra EH,Vaher U,Borggraefe I,Talvik I,Talvik T,Kluger G,Francois LL,Lesca G,de Bellescize J,Blichfeldt S,Chatron N,Holert N,Jacobs J,Swinkels M,Betzler C,Syrbe S,Nikanorova M,Myers CT,Larsen LH,Vejzovic S,Pendziwiat M,von Spiczak S,Hopkins S,Dubbs H,Mang Y,Mukhin K,Holthausen H,van Gassen KL,Dahl HA,Tommerup N,Mefford HC,Rubboli G,Guerrini R,Lemke JR,Lerche H,Muhle H,Maljevic S, Neurology. January 31, 2017; 88(5):1526-632X.

Using Xenopus to understand human disease and developmental disorders., Sater AK,Moody SA, Genesis. January 1, 2017; 55(1-2):1526-968X.

Mechanosensory Stimulation Evokes Acute Concussion-Like Behavior by Activating GIRKs Coupled to Muscarinic Receptors in a Simple Vertebrate., Li WC,Zhu XY,Ritson E, eNeuro. January 1, 2017; 4(2):2373-2822.

Antidepressant, anticonvulsant and antinociceptive effects of 3'-methoxy-6-methylflavone and 3'-hydroxy-6-methylflavone may involve GABAergic mechanisms., Karim N,Khan I,Ahmad N,Umar MN,Gavande N, Pharmacol Rep. October 1, 2017; 69(5):1734-1140.

The Xenopus tadpole: An in vivo model to screen drugs favoring remyelination., Mannioui A,Vauzanges Q,Fini JB,Henriet E,Sekizar S,Azoyan L,Thomas JL,Pasquier DD,Giovannangeli C,Demeneix B,Lubetzki C,Zalc B, Mult Scler. October 1, 2018; 24(11):1477-0970.

The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery., Toriyama M,Lee C,Lee C,Lee C,Taylor SP,Duran I,Cohn DH,Bruel AL,Tabler JM,Drew K,Kelly MR,Kim S,Park TJ,Braun DA,Pierquin G,Biver A,Wagner K,Malfroot A,Panigrahi I,Franco B,Al-Lami HA,Yeung Y,Choi YJ,Duffourd Y,Faivre L,Rivière JB,Chen J,Liu KJ,Liu KJ,Marcotte EM,Hildebrandt F,Thauvin-Robinet C,Krakow D,Jackson PK,Wallingford JB, Nat Genet. June 1, 2016; 48(6):1546-1718.

Rare GABRA3 variants are associated with epileptic seizures, encephalopathy and dysmorphic features., Niturad CE,Lev D,Kalscheuer VM,Charzewska A,Schubert J,Lerman-Sagie T,Kroes HY,Oegema R,Traverso M,Specchio N,Lassota M,Chelly J,Bennett-Back O,Carmi N,Koffler-Brill T,Iacomino M,Trivisano M,Capovilla G,Striano P,Nawara M,Rzonca S,Fischer U,Bienek M,Jensen C,Hu H,Thiele H,Altmüller J,Krause R,May P,Becker F,Balling R,Biskup S,Haas SA,Nürnberg P,van Gassen KLI,Lerche H,Zara F,Maljevic S,Leshinsky-Silver E, Brain. November 1, 2017; 140(11):1460-2156.

Clinical spectrum and genotype-phenotype associations of KCNA2-related encephalopathies., Masnada S,Hedrich UBS,Gardella E,Schubert J,Kaiwar C,Klee EW,Lanpher BC,Gavrilova RH,Synofzik M,Bast T,Gorman K,King MD,Allen NM,Conroy J,Ben Zeev B,Tzadok M,Korff C,Dubois F,Ramsey K,Narayanan V,Serratosa JM,Giraldez BG,Helbig I,Marsh E,O'Brien M,Bergqvist CA,Binelli A,Porter B,Zaeyen E,Horovitz DD,Wolff M,Marjanovic D,Caglayan HS,Arslan M,Pena SDJ,Sisodiya SM,Balestrini S,Syrbe S,Veggiotti P,Lemke JR,Møller RS,Lerche H,Rubboli G, Brain. September 1, 2017; 140(9):1460-2156.

A De Novo Mutation in the Sodium-Activated Potassium Channel KCNT2 Alters Ion Selectivity and Causes Epileptic Encephalopathy., Gururaj S,Palmer EE,Sheehan GD,Kandula T,Macintosh R,Ying K,Morris P,Tao J,Dias KR,Zhu Y,Dinger ME,Cowley MJ,Kirk EP,Roscioli T,Sachdev R,Duffey ME,Bye A,Bhattacharjee A, Cell Rep. October 24, 2017; 21(4):2211-1247.

Gain-of-function HCN2 variants in genetic epilepsy., Li M,Maljevic S,Phillips AM,Petrovski S,Hildebrand MS,Burgess R,Mount T,Zara F,Striano P,Schubert J,Thiele H,Nürnberg P,Wong M,Weisenberg JL,Thio LL,Lerche H,Scheffer IE,Berkovic SF,Petrou S,Reid CA, Hum Mutat. February 1, 2018; 39(2):1098-1004.

A proteomic analysis of LRRK2 binding partners reveals interactions with multiple signaling components of the WNT/PCP pathway., Salašová A,Yokota C,Potěšil D,Zdráhal Z,Bryja V,Arenas E, Mol Neurodegener. July 11, 2017; 12(1):1750-1326.

Clinical and molecular characterization of KCNT1-related severe early-onset epilepsy., McTague A,Nair U,Malhotra S,Meyer E,Trump N,Gazina EV,Papandreou A,Ngoh A,Ackermann S,Ambegaonkar G,Appleton R,Desurkar A,Eltze C,Kneen R,Kumar AV,Lascelles K,Montgomery T,Ramesh V,Samanta R,Scott RH,Tan J,Whitehouse W,Poduri A,Scheffer IE,Chong WKK,Cross JH,Topf M,Petrou S,Kurian MA, Neurology. January 2, 2018; 90(1):1526-632X.

Functional Reintegration of Sensory Neurons and Transitional Dendritic Reduction of Mitral/Tufted Cells during Injury-Induced Recovery of the Larval Xenopus Olfactory Circuit., Hawkins SJ,Weiss L,Offner T,Dittrich K,Hassenklöver T,Manzini I, Front Cell Neurosci. July 21, 2017; 11:1662-5102.

Targeted deletion of the aquaglyceroporin AQP9 is protective in a mouse model of Parkinson's disease., Stahl K,Rahmani S,Prydz A,Skauli N,MacAulay N,Mylonakou MN,Torp R,Skare Ø,Berg T,Leergaard TB,Paulsen RE,Ottersen OP,Amiry-Moghaddam M, PLoS One. January 1, 2018; 13(3):1932-6203.

Functional variants in HCN4 and CACNA1H may contribute to genetic generalized epilepsy., Becker F,Reid CA,Hallmann K,Tae HS,Phillips AM,Teodorescu G,Weber YG,Kleefuss-Lie A,Elger C,Perez-Reyes E,Petrou S,Kunz WS,Lerche H,Maljevic S, Epilepsia Open. August 5, 2017; 2(3):2470-9239.

The Effects of 4-Hydroxybenzoic Acid Identified from Bamboo (Dendrocalamus asper) Shoots on Kv1.4 Channel., Zhang J,Mohamad FH,Wong JH,Mohamad H,Ismail AH,Mohamed Yusoff AA,Osman H,Wong KT,Idris Z,Abdullah JM, Malays J Med Sci. February 1, 2018; 25(1):1394-195X.

Identification of a cono-RFamide from the venom of Conus textile that targets ASIC3 and enhances muscle pain., Reimers C,Lee CH,Lee CH,Lee CH,Kalbacher H,Tian Y,Hung CH,Schmidt A,Prokop L,Kauferstein S,Mebs D,Chen CC,Gründer S, Proc Natl Acad Sci U S A. April 25, 2017; 114(17):1091-6490.

Rare coding variants in genes encoding GABAA receptors in genetic generalised epilepsies: an exome-based case-control study., May P,Girard S,Harrer M,Bobbili DR,Schubert J,Wolking S,Becker F,Lachance-Touchette P,Meloche C,Gravel M,Niturad CE,Knaus J,De Kovel C,Toliat M,Polvi A,Iacomino M,Guerrero-López R,Baulac S,Marini C,Thiele H,Altmüller J,Jabbari K,Ruppert AK,Jurkowski W,Lal D,Rusconi R,Cestèle S,Terragni B,Coombs ID,Reid CA,Striano P,Caglayan H,Siren A,Everett K,Møller RS,Hjalgrim H,Muhle H,Helbig I,Kunz WS,Weber YG,Weckhuysen S,Jonghe P,Sisodiya SM,Nabbout R,Franceschetti S,Coppola A,Vari MS,Kasteleijn-Nolst Trenité D,Baykan B,Ozbek U,Bebek N,Klein KM,Rosenow F,Nguyen DK,Dubeau F,Carmant L,Lortie A,Desbiens R,Clément JF,Cieuta-Walti C,Sills GJ,Auce P,Francis B,Johnson MR,Marson AG,Berghuis B,Sander JW,Avbersek A,McCormack M,Cavalleri GL,Delanty N,Depondt C,Krenn M,Zimprich F,Peter S,Nikanorova M,Kraaij R,van Rooij J,Balling R,Ikram MA,Uitterlinden AG,Avanzini G,Schorge S,Petrou S,Mantegazza M,Sander T,LeGuern E,Serratosa JM,Koeleman BPC,Palotie A,Lehesjoki AE,Nothnagel M,Nürnberg P,Maljevic S,Zara F,Cossette P,Krause R,Lerche H, Lancet Neurol. August 1, 2018; 17(8):1474-4465.

Lack of response to quinidine in KCNT1-related neonatal epilepsy., Numis AL,Nair U,Datta AN,Sands TT,Oldham MS,Patel A,Li M,Gazina E,Petrou S,Cilio MR, Epilepsia. October 1, 2018; 59(10):1528-1167.

S4-S5 linker movement during activation and inactivation in voltage-gated K+ channels., Kalstrup T,Blunck R, Proc Natl Acad Sci U S A. July 17, 2018; 115(29):1091-6490.

A novel GABAergic dysfunction in human Dravet syndrome., Ruffolo G,Cifelli P,Roseti C,Thom M,van Vliet EA,Limatola C,Aronica E,Palma E, Epilepsia. November 1, 2018; 59(11):1528-1167.

De novo pathogenic variants in neuronal differentiation factor 2 (NEUROD2) cause a form of early infantile epileptic encephalopathy., Sega AG,Mis EK,Lindstrom K,Mercimek-Andrews S,Ji W,Cho MT,Juusola J,Konstantino M,Jeffries L,Khokha MK,Lakhani SA, J Med Genet. February 1, 2019; 56(2):1468-6244.

The low binding affinity of D-serine at the ionotropic glutamate receptor GluD2 can be attributed to the hinge region., Tapken D,Steffensen TB,Leth R,Kristensen LB,Gerbola A,Gajhede M,Jørgensen FS,Olsen L,Kastrup JS, Sci Rep. April 7, 2017; 7:2045-2322.

HCN2 Rescues brain defects by enforcing endogenous voltage pre-patterns., Pai VP,Pietak A,Willocq V,Ye B,Shi NQ,Levin M, Nat Commun. March 8, 2018; 9(1):2041-1723.

The Frog Xenopus as a Model to Study Joubert Syndrome: The Case of a Human Patient With Compound Heterozygous Variants in PIBF1., Ott T,Kaufmann L,Granzow M,Hinderhofer K,Bartram CR,Theiß S,Seitz A,Paramasivam N,Schulz A,Moog U,Blum M,Evers CM, Front Physiol. January 1, 2019; 10:1664-042X.

A de novo Ser111Thr variant in aquaporin-4 in a patient with intellectual disability, transient signs of brain ischemia, transient cardiac hypertrophy, and progressive gait disturbance., Berland S,Toft-Bertelsen TL,Aukrust I,Byska J,Vaudel M,Bindoff LA,MacAulay N,Houge G, Cold Spring Harb Mol Case Stud. February 1, 2018; 4(1):2373-2873.

Visualizing flow in an intact CSF network using optical coherence tomography: implications for human congenital hydrocephalus., Date P,Ackermann P,Furey C,Fink IB,Jonas S,Khokha MK,Kahle KT,Deniz E, Sci Rep. April 17, 2019; 9(1):2045-2322.

Aβ1-42 triggers the generation of a retrograde signaling complex from sentinel mRNAs in axons., Walker CA,Randolph LK,Matute C,Alberdi E,Baleriola J,Hengst U, EMBO Rep. July 1, 2018; 19(7):1469-3178.

Functional characterization of SMN evolution in mouse models of SMA., Osman EY,Bolding MR,Villalón E,Kaifer KA,Lorson ZC,Tisdale S,Hao Y,Conant GC,Pires JC,Pellizzoni L,Lorson CL, Sci Rep. July 1, 2019; 9(1):2045-2322.

The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function., Silbernagel N,Walecki M,Schäfer MK,Kessler M,Zobeiri M,Rinné S,Kiper AK,Komadowski MA,Vowinkel KS,Wemhöner K,Fortmüller L,Schewe M,Dolga AM,Scekic-Zahirovic J,Matschke LA,Culmsee C,Baukrowitz T,Monassier L,Ullrich ND,Dupuis L,Just S,Budde T,Fabritz L,Decher N, FASEB J. November 1, 2018; 32(11):1530-6860.

Comparative Embryonic Spatio-Temporal Expression Profile Map of the Xenopus P2X Receptor Family., Blanchard C,Boué-Grabot E,Massé K, Front Cell Neurosci. January 1, 2019; 13:1662-5102.

Migraine-Associated TRESK Mutations Increase Neuronal Excitability through Alternative Translation Initiation and Inhibition of TREK., Royal P,Andres-Bilbe A,Ávalos Prado P,Verkest C,Wdziekonski B,Schaub S,Baron A,Lesage F,Gasull X,Levitz J,Sandoz G, Neuron. January 16, 2019; 101(2):0896-6273.

De novo variants in SLC12A6 cause sporadic early-onset progressive sensorimotor neuropathy., Park J,Flores BR,Scherer K,Kuepper H,Rossi M,Rupprich K,Rautenberg M,Deininger N,Weichselbaum A,Grimm A,Sturm M,Grasshoff U,Delpire E,Haack TB, J Med Genet. April 1, 2020; 57(4):1468-6244.

Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis., Corkins ME,Krneta-Stankic V,Kloc M,McCrea PD,Gladden AB,Miller RK, PLoS One. January 1, 2019; 14(8):1932-6203.

Atom-by-atom tuning of the electrostatic potassium-channel modulator dehydroabietic acid., Silverå Ejneby M,Wu X,Ottosson NE,Münger EP,Lundström I,Konradsson P,Elinder F, J Gen Physiol. May 7, 2018; 150(5):1540-7748.

Functional genomics of epilepsy-associated mutations in the GABAA receptor subunits reveal that one mutation impairs function and two are catastrophic., Absalom NL,Ahring PK,Liao VW,Balle T,Jiang T,Anderson LL,Arnold JC,McGregor IS,Bowen MT,Chebib M, J Biol Chem. April 12, 2019; 294(15):1083-351X.

Coadministered cannabidiol and clobazam: Preclinical evidence for both pharmacodynamic and pharmacokinetic interactions., Anderson LL,Absalom NL,Abelev SV,Low IK,Doohan PT,Martin LJ,Chebib M,McGregor IS,Arnold JC, Epilepsia. November 1, 2019; 60(11):1528-1167.

CFAP43 modulates ciliary beating in mouse and Xenopus., Rachev E,Schuster-Gossler K,Fuhl F,Ott T,Tveriakhina L,Beckers A,Hegermann J,Boldt K,Mai M,Kremmer E,Ueffing M,Blum M,Gossler A, Dev Biol. March 15, 2020; 459(2):1095-564X.

RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis., Naert T,Dimitrakopoulou D,Tulkens D,Demuynck S,Carron M,Noelanders R,Eeckhout L,Van Isterdael G,Deforce D,Vanhove C,Van Dorpe J,Creytens D,Vleminckx K,Vleminckx K, Oncogene. March 1, 2020; 39(13):0950-9232.

FERM domain-containing protein 6 identifies a subpopulation of varicose nerve fibers in different vertebrate species., Beck J,Kressel M, Cell Tissue Res. July 1, 2020; 381(1):1432-0878.

Epilepsy-associated mutations in the voltage sensor of KCNQ3 affect voltage dependence of channel opening., Barro-Soria R, J Gen Physiol. February 4, 2019; 151(2):1540-7748.

The GRIA3 c.2477G > A Variant Causes an Exaggerated Startle Reflex, Chorea, and Multifocal Myoclonus., Piard J,Béreau M,XiangWei W,Wirth T,Amsallem D,Buisson L,Richard P,Liu N,Xu Y,Xu Y,Myers SJ,Traynelis SF,Chelly J,Anheim M,Raynaud M,Maldergem LV,Yuan H, Mov Disord. July 1, 2020; 35(7):1531-8257.

The FOXJ1 target Cfap206 is required for sperm motility, mucociliary clearance of the airways and brain development., Beckers A,Adis C,Schuster-Gossler K,Tveriakhina L,Ott T,Fuhl F,Hegermann J,Boldt K,Serth K,Rachev E,Alten L,Kremmer E,Ueffing M,Blum M,Gossler A, Development. June 15, 2020; 147(21):1477-9129.

KCNC1-related disorders: new de novo variants expand the phenotypic spectrum., Park J,Koko M,Hedrich UBS,Hermann A,Cremer K,Haberlandt E,Grimmel M,Alhaddad B,Beck-Woedl S,Harrer M,Karall D,Kingelhoefer L,Tzschach A,Matthies LC,Strom TM,Ringelstein EB,Sturm M,Engels H,Wolff M,Lerche H,Haack TB, Ann Clin Transl Neurol. July 1, 2019; 6(7):2328-9503.

Association of A Novel Splice Site Mutation in P/Q-Type Calcium Channels with Childhood Epilepsy and Late-Onset Slowly Progressive Non-Episodic Cerebellar Ataxia., Stendel C,D'Adamo MC,Wiessner M,Dusl M,Cenciarini M,Belia S,Nematian-Ardestani E,Bauer P,Senderek J,Klopstock T,Pessia M, Int J Mol Sci. May 27, 2020; 21(11):1422-0067.

Electromechanical coupling of the Kv1.1 voltage-gated K+ channel is fine-tuned by the simplest amino acid residue in the S4-S5 linker., Hasan S,Megaro A,Cenciarini M,Coretti L,Botti FM,Imbrici P,Steinbusch HWM,Hunter T,Hunter G,Pessia M,D'Adamo MC, Pflugers Arch. July 1, 2020; 472(7):1432-2013.

DLG5 variants are associated with multiple congenital anomalies including ciliopathy phenotypes., Marquez J,Mann N,Arana K,Deniz E,Ji W,Konstantino M,Mis EK,Deshpande C,Jeffries L,McGlynn J,Hugo H,Widmeier E,Konrad M,Tasic V,Morotti R,Baptista J,Ellard S,Lakhani SA,Hildebrandt F,Khokha MK, J Med Genet. July 1, 2021; 58(7):1468-6244.

Mambalgin-2 Induces Cell Cycle Arrest and Apoptosis in Glioma Cells via Interaction with ASIC1a., Bychkov M,Shulepko M,Osmakov D,Andreev Y,Sudarikova A,Vasileva V,Pavlyukov MS,Latyshev YA,Potapov AA,Kirpichnikov M,Shenkarev ZO,Lyukmanova E, Cancers (Basel). July 8, 2020; 12(7):2072-6694.

Interplay of TRIM2 E3 Ubiquitin Ligase and ALIX/ESCRT Complex: Control of Developmental Plasticity During Early Neurogenesis., Lokapally A,Neuhaus H,Herfurth J,Hollemann T, Cells. July 20, 2020; 9(7):2073-4409.

In vitro and in vivo characterization of Lu AA41178: A novel, brain penetrant, pan-selective Kv7 potassium channel opener with efficacy in preclinical models of epileptic seizures and psychiatric disorders., Grupe M,Bentzen BH,Benned-Jensen T,Nielsen V,Frederiksen K,Jensen HS,Jacobsen AM,Skibsbye L,Sams AG,Grunnet M,Rottländer M,Bastlund JF, Eur J Pharmacol. November 15, 2020; 887:1879-0712.

Characterization of AN317, a novel selective agonist of α6β2-containing nicotinic acetylcholine receptors., Sandager-Nielsen K,Ahring PK,Klein J,van Hout M,Thaneshwaran S,Dos Santos AB,Jacobsen TA,Amrutkar DV,Peters D,Jensen AA,Kohlmeier KA,Christophersen P,Dyhring T, Biochem Pharmacol. April 1, 2020; 174:1873-2968.

Tetrapeptide Ac-HAEE-NH2 Protects α4β2 nAChR from Inhibition by Aβ., Barykin EP,Garifulina AI,Tolstova AP,Anashkina AA,Adzhubei AA,Mezentsev YV,Shelukhina IV,Kozin SA,Tsetlin VI,Makarov AA, Int J Mol Sci. August 29, 2020; 21(17):1422-0067.

Isoform-Selective KCNA1 Potassium Channel Openers Built from Glycine., Manville RW,Abbott GW, J Pharmacol Exp Ther. June 1, 2020; 373(3):1521-0103.

Alignment of Alzheimer's disease amyloid β-peptide and klotho., Lehrer S,Rheinstein PH, World Acad Sci J. January 1, 2020; 2(6):2632-2919.

A Common Kinetic Property of Mutations Linked to Episodic Ataxia Type 1 Studied in the Shaker Kv Channel., Zhao J,Petitjean D,Haddad GA,Batulan Z,Blunck R, Int J Mol Sci. October 14, 2020; 21(20):1422-0067.

The anticonvulsant zonisamide positively modulates recombinant and native glycine receptors at clinically relevant concentrations., Devenish SO,Winters BL,Anderson LL,Arnold JC,McGregor IS,Vaughan CW,Chebib M,Absalom NL, Neuropharmacology. January 1, 2021; 182:1873-7064.

Voltage-Dependent Dopamine Potency at D1-Like Dopamine Receptors., Ågren R,Sahlholm K, Front Pharmacol. April 7, 2020; 11:1663-9812.

Functional Integrity of Synapses in the Central Nervous System of Cognitively Intact Individuals with High Alzheimer's Disease Neuropathology Is Associated with Absence of Synaptic Tau Oligomers., Singh A,Allen D,Fracassi A,Tumurbaatar B,Natarajan C,Scaduto P,Woltjer R,Kayed R,Limon A,Krishnan B,Taglialatela G, J Alzheimers Dis. January 1, 2020; 78(4):1875-8908.

A System for Assessing Dual Action Modulators of Glycine Transporters and Glycine Receptors., Sheipouri D,Gallagher CI,Shimmon S,Rawling T,Vandenberg RJ, Biomolecules. November 30, 2020; 10(12):2218-273X.

Characterization of the GABRB2-Associated Neurodevelopmental Disorders., El Achkar CM,Harrer M,Smith L,Kelly M,Iqbal S,Maljevic S,Niturad CE,Vissers LELM,Poduri A,Yang E,Lal D,Lerche H,Møller RS,Olson HE, Ann Neurol. March 1, 2021; 89(3):1531-8249.

Familial neonatal seizures caused by the Kv7.3 selectivity filter mutation T313I., Maghera J,Li J,Lamothe SM,Braun M,Appendino JP,Au PYB,Kurata HT, Epilepsia Open. October 17, 2020; 5(4):2470-9239.

Differential Coassembly of α1-GABAARs Associated with Epileptic Encephalopathy., Hannan S,Affandi AHB,Minere M,Jones C,Goh P,Warnes G,Popp B,Trollmann R,Nizetic D,Smart TG, J Neurosci. July 15, 2020; 40(29):1529-2401.

Xenopus leads the way: Frogs as a pioneering model to understand the human brain., Exner CRT,Willsey HR, Genesis. February 1, 2021; 59(1-2):1526-968X.

Editorial: Xenopus Models of Organogenesis and Disease., Griffin JN,Liu KJ,Liu KJ,Sempou E, Front Physiol. January 1, 2020; 11:1664-042X.

TRESK and TREK-2 two-pore-domain potassium channel subunits form functional heterodimers in primary somatosensory neurons., Lengyel M,Czirják G,Jacobson DA,Enyedi P, J Biol Chem. August 28, 2020; 295(35):1083-351X.

Aquatic models of human ciliary diseases., Corkins ME,Krneta-Stankic V,Kloc M,Miller RK, Genesis. February 1, 2021; 59(1-2):1526-968X.

Quantifying the dose-dependent impact of intracellular amyloid beta in a mathematical model of calcium regulation in xenopus oocyte., Minicucci J,Alfond M,Demuro A,Gerberry D,Latulippe J, PLoS One. January 28, 2021; 16(1):1932-6203.

Sleep-related hypermotor epilepsy associated mutations uncover important kinetic roles of α4β2- nicotinic acetylcholine receptor intracellular structures., Weltzin MM,George AA,Lukas RJ,Whiteaker P, PLoS One. March 3, 2021; 16(3):1932-6203.

Cation leak underlies neuronal excitability in an HCN1 developmental and epileptic encephalopathy., Bleakley LE,McKenzie CE,Soh MS,Forster IC,Pinares-Garcia P,Sedo A,Kathirvel A,Churilov L,Jancovski N,Maljevic S,Berkovic SF,Scheffer IE,Petrou S,Santoro B,Reid CA, Brain. August 17, 2021; 144(7):1460-2156.

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Aquatic Freshwater Vertebrate Models of Epilepsy Pathology: Past Discoveries and Future Directions for Therapeutic Discovery., Williams RE,Mruk K, Int J Mol Sci. August 3, 2022; 23(15):1422-0067.

Functional characterization of a novel TP53RK mutation identified in a family with Galloway-Mowat syndrome., Treimer E,Kalayci T,Schumann S,Suer I,Greco S,Schanze D,Schmeisser MJ,Kühl SJ,Zenker M, Hum Mutat. December 1, 2022; 43(12):1098-1004.

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Advancements in the use of xenopus oocytes for modelling neurological disease for novel drug discovery., O'Connor EC,Kambara K,Bertrand D, Expert Opin Drug Discov. February 1, 2024; 19(2):1746-045X.

GRIN2A mutation and early-onset epileptic encephalopathy: personalized therapy with memantine., Pierson TM,Yuan H,Marsh ED,Fuentes-Fajardo K,Adams DR,Markello T,Golas G,Simeonov DR,Holloman C,Tankovic A,Karamchandani MM,Schreiber JM,Mullikin JC,Tifft CJ,Toro C,Boerkoel CF,Traynelis SF,Gahl WA, Ann Clin Transl Neurol. March 1, 2014; 1(3):2328-9503.

Remarkable effect of transdermal nicotine in children with CHRNA4-related autosomal dominant sleep-related hypermotor epilepsy., Lossius K,de Saint Martin A,Myren-Svelstad S,Bjørnvold M,Minken G,Seegmuller C,Valenti Hirsch MP,Chelly J,Steinlein O,Picard F,Brodtkorb E, Epilepsy Behav. April 1, 2020; 105:1525-5069.

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Enhanced Membrane Incorporation of H289Y Mutant GluK1 Receptors from the Audiogenic Seizure-Prone GASH/Sal Model: Functional and Morphological Impacts on Xenopus Oocytes., Díaz-Rodríguez SM,Ivorra I,Espinosa J,Vegar C,Herrero-Turrión MJ,López DE,Gómez-Nieto R,Alberola-Die A, Int J Mol Sci. November 28, 2023; 24(23):1422-0067.

Alcohol induces neural tube defects by reducing retinoic acid signaling and promoting neural plate expansion., Edri T,Cohen D,Shabtai Y,Fainsod A, Front Cell Dev Biol. January 1, 2023; 11:2296-634X.

Selective block of human Kv1.1 channels and an epilepsy-associated gain-of-function mutation by AETX-K peptide., Zhao R,Qasim A,Sophanpanichkul P,Dai H,Nayak M,Sher I,Chill J,Goldstein SAN, FASEB J. January 1, 2024; 38(1):1530-6860.

A novel SMARCC1 BAFopathy implicates neural progenitor epigenetic dysregulation in human hydrocephalus., Singh AK,Allington G,Viviano S,McGee S,Kiziltug E,Ma S,Zhao S,Mekbib KY,Shohfi JP,Duy PQ,DeSpenza T,Furey CG,Reeves BC,Smith H,Sousa AMM,Cherskov A,Allocco A,Nelson-Williams C,Haider S,Rizvi SRA,Alper SL,Sestan N,Shimelis H,Walsh LK,Lifton RP,Moreno-De-Luca A,Jin SC,Kruszka P,Deniz E,Kahle KT, Brain. December 21, 2023; :1460-2156.

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Novel insights into voltage-gated ion channels: Translational breakthroughs in medical oncology., Sakellakis M,Yoon SM,Reet J,Chalkias A, Channels (Austin). December 1, 2024; 18(1):1933-6969.