Summary Literature (107)

Xenbase Articles :
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The Wnt-dependent signaling pathways as target in oncology drug discovery., Janssens N,Janicot M,Perera T, Invest New Drugs. July 1, 2006; 24(4):0167-6997.

Effects of the abused inhalant toluene on ethanol-sensitive potassium channels expressed in oocytes., Del Re AM,Dopico AM,Woodward JJ, Dev Biol. May 4, 2006; 1087(1):0012-1606.

A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization., Hurst RS,Hajós M,Raggenbass M,Wall TM,Higdon NR,Lawson JA,Rutherford-Root KL,Berkenpas MB,Hoffmann WE,Piotrowski DW,Groppi VE,Allaman G,Ogier R,Bertrand S,Bertrand D,Arneric SP, J Neurosci. April 27, 2005; 25(17):1529-2401.

Ethanol exposure affects gene expression in the embryonic organizer and reduces retinoic acid levels., Yelin R,Schyr RB,Kot H,Zins S,Frumkin A,Pillemer G,Fainsod A, Dev Biol. March 1, 2005; 279(1):1095-564X.

Rett syndrome: clinical review and genetic update., Weaving LS,Ellaway CJ,Gécz J,Christodoulou J, J Med Genet. January 1, 2005; 42(1):1468-6244.

Transgenic animal models of tauopathies., Lee VM,Kenyon TK,Trojanowski JQ, Biochim Biophys Acta. January 3, 2005; 1739(2-3):0006-3002.

Differential inhibition of nicotine- and acetylcholine-evoked currents through alpha4beta2 neuronal nicotinic receptors by tobacco cembranoids in Xenopus oocytes., Eaton MJ,Ospina CA,Rodríguez AD,Eterovi VA, Neurosci Lett. August 5, 2004; 366(1):1872-7972.

A critical role of Pax6 in alcohol-induced fetal microcephaly., Peng Y,Yang PH,Ng SS,Wong OG,Liu J,He ML,Kung HF,Lin MC, Neurobiol Dis. July 1, 2004; 16(2):1095-953X.

Catalase and peroxiredoxin 5 protect Xenopus embryos against alcohol-induced ocular anomalies., Peng Y,Yang PH,Guo Y,Ng SS,Liu J,Fung PC,Tay D,Ge J,He ML,Kung HF,Lin MC, Invest Ophthalmol Vis Sci. January 1, 2004; 45(1):1552-5783.

A mutant form of MeCP2 protein associated with human Rett syndrome cannot be displaced from methylated DNA by notch in Xenopus embryos., Stancheva I,Collins AL,Van den Veyver IB,Zoghbi H,Meehan RR, Mol Cell. August 1, 2003; 12(2):1097-4164.

Differences in neuroanatomical sites of apoD elevation discriminate between schizophrenia and bipolar disorder., Thomas EA,Dean B,Scarr E,Copolov D,Sutcliffe JG, Mol Psychiatry. February 1, 2003; 8(2):1476-5578.

Craniofacial malformation in Xenopus laevis tadpoles caused by the exposure of early embryos to ethanol., Nakatsuji N, Teratology. October 1, 1983; 28(2):0040-3709.

Early molecular effects of ethanol during vertebrate embryogenesis., Yelin R,Kot H,Yelin D,Fainsod A, Differentiation. June 1, 2007; 75(5):1432-0436.

Functional significance of the kainate receptor GluR6(M836I) mutation that is linked to autism., Strutz-Seebohm N,Korniychuk G,Schwarz R,Baltaev R,Ureche ON,Mack AF,Ma ZL,Hollmann M,Lang F,Seebohm G, Cell Physiol Biochem. January 1, 2006; 18(4-5):1421-9778.

Neutralization of a negative charge in the S1-S2 region of the KV7.2 (KCNQ2) channel affects voltage-dependent activation in neonatal epilepsy., Wuttke TV,Penzien J,Fauler M,Seebohm G,Lehmann-Horn F,Lerche H,Jurkat-Rott K, J Physiol. January 15, 2008; 586(2):0022-3751.

Microtransplantation of neurotransmitter receptors from postmortem autistic brains to Xenopus oocytes., Limon A,Reyes-Ruiz JM,Miledi R, Proc Natl Acad Sci U S A. August 5, 2008; 105(31):1091-6490.

Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A., Ogawa Y,Nonaka Y,Goto T,Ohnishi E,Hiramatsu T,Kii I,Yoshida M,Ikura T,Onogi H,Shibuya H,Hosoya T,Ito N,Hagiwara M, Nat Commun. October 5, 2010; 1:2041-1723.

The TM2 6' position of GABA(A) receptors mediates alcohol inhibition., Johnson WD,Howard RJ,Trudell JR,Harris RA, J Pharmacol Exp Ther. February 1, 2012; 340(2):1521-0103.

Modeling human neurodevelopmental disorders in the Xenopus tadpole: from mechanisms to therapeutic targets., Pratt KG,Khakhalin AS, Dis Model Mech. September 1, 2013; 6(5):1754-8411.

GRIN2B mutations in West syndrome and intellectual disability with focal epilepsy., Lemke JR,Hendrickx R,Geider K,Laube B,Schwake M,Harvey RJ,James VM,Pepler A,Steiner I,Hörtnagel K,Neidhardt J,Ruf S,Wolff M,Bartholdi D,Caraballo R,Platzer K,Suls A,De Jonghe P,Biskup S,Weckhuysen S, Ann Neurol. January 1, 2014; 75(1):1531-8249.

Avermectins differentially affect ethanol intake and receptor function: implications for developing new therapeutics for alcohol use disorders., Asatryan L,Yardley MM,Khoja S,Trudell JR,Hyunh N,Louie SG,Petasis NA,Alkana RL,Davies DL, Int J Neuropsychopharmacol. June 1, 2014; 17(6):1469-5111.

The different effects on cranial and trunk neural crest cell behaviour following exposure to a low concentration of alcohol in vitro., Czarnobaj J,Bagnall KM,Bamforth JS,Milos NC, Arch Oral Biol. May 1, 2014; 59(5):1879-1506.

5-Mehtyltetrahydrofolate rescues alcohol-induced neural crest cell migration abnormalities., Shi Y,Shi Y,Li J,Chen C,Gong M,Chen Y,Chen Y,Liu Y,Chen J,Li T,Song W, Mol Brain. September 16, 2014; 7:1756-6606.

The splicing factor PQBP1 regulates mesodermal and neural development through FGF signaling., Iwasaki Y,Thomsen GH, Development. October 1, 2014; 141(19):1477-9129.

Valproate-induced neurodevelopmental deficits in Xenopus laevis tadpoles., James EJ,Gu J,Ramirez-Vizcarrondo CM,Hasan M,Truszkowski TL,Tan Y,Oupravanh PM,Khakhalin AS,Aizenman CD, J Neurosci. February 18, 2015; 35(7):1529-2401.

Heterologous expression of NaV1.9 chimeras in various cell systems., Goral RO,Leipold E,Nematian-Ardestani E,Heinemann SH, Pflugers Arch. December 1, 2015; 467(12):1432-2013.

Genetically induced dysfunctions of Kir2.1 channels: implications for short QT3 syndrome and autism-epilepsy phenotype., Ambrosini E,Sicca F,Brignone MS,D'Adamo MC,Napolitano C,Servettini I,Moro F,Ruan Y,Guglielmi L,Pieroni S,Servillo G,Lanciotti A,Valvo G,Catacuzzeno L,Franciolini F,Molinari P,Marchese M,Grottesi A,Guerrini R,Santorelli FM,Priori S,Pessia M, Hum Mol Genet. September 15, 2014; 23(18):1460-2083.

Transcriptional regulator PRDM12 is essential for human pain perception., Chen YC,Chen YC,Auer-Grumbach M,Matsukawa S,Zitzelsberger M,Themistocleous AC,Strom TM,Samara C,Moore AW,Cho LT,Young GT,Weiss C,Schabhüttl M,Stucka R,Schmid AB,Parman Y,Graul-Neumann L,Heinritz W,Passarge E,Watson RM,Hertz JM,Moog U,Baumgartner M,Valente EM,Pereira D,Restrepo CM,Katona I,Dusl M,Stendel C,Wieland T,Stafford F,Reimann F,von Au K,Finke C,Willems PJ,Nahorski MS,Shaikh SS,Carvalho OP,Nicholas AK,Karbani G,McAleer MA,Cilio MR,McHugh JC,Murphy SM,Irvine AD,Jensen UB,Windhager R,Weis J,Bergmann C,Rautenstrauss B,Baets J,De Jonghe P,Reilly MM,Kropatsch R,Kurth I,Chrast R,Michiue T,Bennett DL,Woods CG,Senderek J, Nat Genet. July 1, 2015; 47(7):1546-1718.

PnPP-19, a Synthetic and Nontoxic Peptide Designed from a Phoneutria nigriventer Toxin, Potentiates Erectile Function via NO/cGMP., Silva CN,Nunes KP,Torres FS,Cassoli JS,Santos DM,Almeida Fde M,Matavel A,Cruz JS,Santos-Miranda A,Nunes AD,Castro CH,Machado de Ávila RA,Chávez-Olórtegui C,Láuar SS,Felicori L,Resende JM,Camargos ER,Borges MH,Cordeiro MN,Peigneur S,Tytgat J,de Lima ME, J Urol. November 1, 2015; 194(5):1527-3792.

Doxepin and imipramine but not fluoxetine reduce the activity of the rat glutamate transporter EAAT3 expressed in Xenopus oocytes., Park HJ,Baik HJ,Kim DY,Lee GY,Woo JH,Zuo Z,Chung RK, BMC Anesthesiol. August 8, 2015; 15:1471-2253.

Functional Impact of 14 Single Nucleotide Polymorphisms Causing Missense Mutations of Human α7 Nicotinic Receptor., Zhang Q,Du Y,Zhang J,Xu X,Xue F,Guo C,Huang Y,Lukas RJ,Chang Y, PLoS One. September 4, 2015; 10(9):1932-6203.

CRISPR/Cas9: An inexpensive, efficient loss of function tool to screen human disease genes in Xenopus., Bhattacharya D,Marfo CA,Li D,Lane M,Khokha MK, Dev Biol. December 15, 2015; 408(2):1095-564X.

Deletions and de novo mutations of SOX11 are associated with a neurodevelopmental disorder with features of Coffin-Siris syndrome., Hempel A,Pagnamenta AT,Blyth M,Mansour S,McConnell V,Kou I,Ikegawa S,Tsurusaki Y,Matsumoto N,Lo-Castro A,Plessis G,Albrecht B,Battaglia A,Taylor JC,Howard MF,Keays D,Sohal AS,Kühl SJ,Kühl SJ,Kini U,McNeill A, J Med Genet. March 1, 2016; 53(3):1468-6244.

Fragile X mental retardation protein knockdown in the developing Xenopus tadpole optic tectum results in enhanced feedforward inhibition and behavioral deficits., Truszkowski TL,James EJ,Hasan M,Wishard TJ,Liu Z,Pratt KG,Cline HT,Aizenman CD, Neural Dev. August 8, 2016; 11(1):1749-8104.

De novo and inherited mutations in the X-linked gene CLCN4 are associated with syndromic intellectual disability and behavior and seizure disorders in males and females., Palmer EE,Stuhlmann T,Weinert S,Haan E,Van Esch H,Holvoet M,Boyle J,Leffler M,Raynaud M,Moraine C,van Bokhoven H,Kleefstra T,Kahrizi K,Najmabadi H,Ropers HH,Delgado MR,Sirsi D,Golla S,Sommer A,Pietryga MP,Chung WK,Wynn J,Rohena L,Bernardo E,Hamlin D,Faux BM,Grange DK,Manwaring L,Tolmie J,Joss S,Cobben JM,Duijkers FAM,Goehringer JM,Challman TD,Hennig F,Fischer U,Grimme A,Suckow V,Musante L,Nicholl J,Shaw M,Lodh SP,Niu Z,Rosenfeld JA,Stankiewicz P,Jentsch TJ,Gecz J,Field M,Kalscheuer VM, Mol Psychiatry. February 1, 2018; 23(2):1476-5578.

Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy., Sicca F,Ambrosini E,Marchese M,Sforna L,Servettini I,Valvo G,Brignone MS,Lanciotti A,Moro F,Grottesi A,Catacuzzeno L,Baldini S,Hasan S,D'Adamo MC,Franciolini F,Molinari P,Santorelli FM,Pessia M, Sci Rep. September 28, 2016; 6:2045-2322.

Using Xenopus to understand human disease and developmental disorders., Sater AK,Moody SA, Genesis. January 1, 2017; 55(1-2):1526-968X.

Modeling human craniofacial disorders in Xenopus., Dubey A,Saint-Jeannet JP, Curr Pathobiol Rep. March 1, 2017; 5(1):2167-485X.

Antidepressant, anticonvulsant and antinociceptive effects of 3'-methoxy-6-methylflavone and 3'-hydroxy-6-methylflavone may involve GABAergic mechanisms., Karim N,Khan I,Ahmad N,Umar MN,Gavande N, Pharmacol Rep. October 1, 2017; 69(5):1734-1140.

Rare GABRA3 variants are associated with epileptic seizures, encephalopathy and dysmorphic features., Niturad CE,Lev D,Kalscheuer VM,Charzewska A,Schubert J,Lerman-Sagie T,Kroes HY,Oegema R,Traverso M,Specchio N,Lassota M,Chelly J,Bennett-Back O,Carmi N,Koffler-Brill T,Iacomino M,Trivisano M,Capovilla G,Striano P,Nawara M,Rzonca S,Fischer U,Bienek M,Jensen C,Hu H,Thiele H,Altmüller J,Krause R,May P,Becker F,Balling R,Biskup S,Haas SA,Nürnberg P,van Gassen KLI,Lerche H,Zara F,Maljevic S,Leshinsky-Silver E, Brain. November 1, 2017; 140(11):1460-2156.

Structural basis of TRPA1 inhibition by HC-030031 utilizing species-specific differences., Gupta R,Saito S,Mori Y,Itoh SG,Okumura H,Tominaga M, Sci Rep. November 22, 2016; 6:2045-2322.

Katanin-like protein Katnal2 is required for ciliogenesis and brain development in Xenopus embryos., Willsey HR,Walentek P,Exner CRT,Xu Y,Xu Y,Lane AB,Harland RM,Heald R,Santama N, Dev Biol. October 15, 2018; 442(2):1095-564X.

A review of interventions against fetal alcohol spectrum disorder targeting oxidative stress., Zhang Y,Zhang Y,Wang H,Li Y,Peng Y, Int J Dev Neurosci. December 1, 2018; 71:0736-5748.

Functional analysis of a triplet deletion in the gene encoding the sodium glucose transporter 3, a potential risk factor for ADHD., Schäfer N,Friedrich M,Jørgensen ME,Kollert S,Koepsell H,Wischmeyer E,Lesch KP,Geiger D,Döring F, PLoS One. October 4, 2018; 13(10):1932-6203.

Acetaldehyde inhibits retinoic acid biosynthesis to mediate alcohol teratogenicity., Shabtai Y,Bendelac L,Jubran H,Hirschberg J,Fainsod A, Sci Rep. January 10, 2018; 8(1):2045-2322.

HCN2 Rescues brain defects by enforcing endogenous voltage pre-patterns., Pai VP,Pietak A,Willocq V,Ye B,Shi NQ,Levin M, Nat Commun. March 8, 2018; 9(1):2041-1723.

Retinoic acid signaling reduction recapitulates the effects of alcohol on embryo size., Shukrun N,Shabtai Y,Pillemer G,Fainsod A, Genesis. July 1, 2019; 57(7-8):1526-968X.

De Novo SOX4 Variants Cause a Neurodevelopmental Disease Associated with Mild Dysmorphism., Zawerton A,Yao B,Yeager JP,Pippucci T,Haseeb A,Smith JD,Wischmann L,Kühl SJ,Dean JCS,Pilz DT,Holder SE,McNeill A,Graziano C,Lefebvre V, Am J Hum Genet. February 7, 2019; 104(2):1537-6605.

Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA., Desiderio S,Vermeiren S,Van Campenhout C,Kricha S,Malki E,Richts S,Fletcher EV,Vanwelden T,Schmidt BZ,Henningfeld KA,Pieler T,Woods CG,Nagy V,Verfaillie C,Bellefroid EJ, Cell Rep. March 26, 2019; 26(13):2211-1247.

Antinociceptive effects of new pyrazoles compounds mediated by the ASIC-1α channel, TRPV-1 and μMOR receptors., Florentino IF,Silva DPB,Cardoso CS,Menegatti R,de Carvalho FS,Lião LM,Pinto PM,Peigneur S,Costa EA,Tytgat J, Biomed Pharmacother. July 1, 2019; 115:0753-3322.

Rare Diseases of Neurodevelopment: Maintain the Mystery or Use a Dazzling Tool for Investigation? The Case of Rett Syndrome., Ruffolo G,Cifelli P,Miranda-Lourenço C,De Felice E,Limatola C,Sebastião AM,Diógenes MJ,Aronica E,Palma E, Neuroscience. July 15, 2020; 439:1873-7544.

NCBP2 modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and Xenopus laevis models., Singh MD,Jensen M,Lasser M,Huber E,Yusuff T,Pizzo L,Lifschutz B,Desai I,Kubina A,Yennawar S,Kim S,Iyer J,Rincon-Limas DE,Lowery LA,Girirajan S, PLoS Genet. February 13, 2020; 16(2):1553-7404.

Opposite Modulation of RAC1 by Mutations in TRIO Is Associated with Distinct, Domain-Specific Neurodevelopmental Disorders., Barbosa S,Greville-Heygate S,Bonnet M,Godwin A,Fagotto-Kaufmann C,Kajava AV,Laouteouet D,Mawby R,Wai HA,Dingemans AJM,Hehir-Kwa J,Willems M,Capri Y,Mehta SG,Cox H,Goudie D,Vansenne F,Turnpenny P,Vincent M,Cogné B,Lesca G,Hertecant J,Rodriguez D,Keren B,Burglen L,Gérard M,Putoux A,Cantagrel V,Siquier-Pernet K,Rio M,Banka S,Sarkar A,Steeves M,Parker M,Clement E,Moutton S,Tran Mau-Them F,Piton A,de Vries BBA,Guille M,Debant A,Schmidt S,Baralle D, Am J Hum Genet. March 5, 2020; 106(3):1537-6605.

Fetal Alcohol Spectrum Disorder: Embryogenesis Under Reduced Retinoic Acid Signaling Conditions., Fainsod A,Bendelac-Kapon L,Shabtai Y, Subcell Biochem. January 1, 2020; 95:0306-0225.

KCNC1-related disorders: new de novo variants expand the phenotypic spectrum., Park J,Koko M,Hedrich UBS,Hermann A,Cremer K,Haberlandt E,Grimmel M,Alhaddad B,Beck-Woedl S,Harrer M,Karall D,Kingelhoefer L,Tzschach A,Matthies LC,Strom TM,Ringelstein EB,Sturm M,Engels H,Wolff M,Lerche H,Haack TB, Ann Clin Transl Neurol. July 1, 2019; 6(7):2328-9503.

De novo mutations in FBRSL1 cause a novel recognizable malformation and intellectual disability syndrome., Ufartes R,Berger H,Till K,Salinas G,Sturm M,Altmüller J,Nürnberg P,Thiele H,Funke R,Apeshiotis N,Langen H,Wollnik B,Borchers A,Pauli S, Hum Genet. November 1, 2020; 139(11):1432-1203.

The neurodevelopmental disorder risk gene DYRK1A is required for ciliogenesis and control of brain size in Xenopus embryos., Willsey HR,Xu Y,Xu Y,Everitt A,Dea J,Exner CRT,Willsey AJ,State MW,Harland RM, Development. June 22, 2020; 147(21):1477-9129.

Potentiation of Gamma Aminobutyric Acid Receptors (GABAAR) by Ethanol: How Are Inhibitory Receptors Affected?, Förstera B,Castro PA,Moraga-Cid G,Aguayo LG, Front Cell Neurosci. May 6, 2016; 10:1662-5102.

SLC12A2 variants cause a neurodevelopmental disorder or cochleovestibular defect., McNeill A,Iovino E,Mansard L,Vache C,Baux D,Bedoukian E,Cox H,Dean J,Goudie D,Kumar A,Newbury-Ecob R,Fallerini C,Renieri A,Lopergolo D,Mari F,Blanchet C,Willems M,Roux AF,Pippucci T,Delpire E, Brain. August 1, 2020; 143(8):1460-2156.

Preventing Ethanol-Induced Brain and Eye Morphology Defects Using Optogenetics., Pai VP,Adams DS, Bioelectricity. December 1, 2019; 1(4):2576-3113.

In vitro and in vivo characterization of Lu AA41178: A novel, brain penetrant, pan-selective Kv7 potassium channel opener with efficacy in preclinical models of epileptic seizures and psychiatric disorders., Grupe M,Bentzen BH,Benned-Jensen T,Nielsen V,Frederiksen K,Jensen HS,Jacobsen AM,Skibsbye L,Sams AG,Grunnet M,Rottländer M,Bastlund JF, Eur J Pharmacol. November 15, 2020; 887:1879-0712.

A Collision Coupling Model Governs the Activation of Neuronal GIRK1/2 Channels by Muscarinic-2 Receptors., Berlin S,Artzy E,Handklo-Jamal R,Kahanovitch U,Parnas H,Dascal N,Yakubovich D, Front Pharmacol. April 7, 2020; 11:1663-9812.

Disruption of Cav1.2-mediated signaling is a pathway for ketamine-induced pathology., Chen H,Vandorpe DH,Xie X,Alper SL,Zeidel ML,Yu W, Nat Commun. August 28, 2020; 11(1):2041-1723.

Voltage-Dependent Dopamine Potency at D1-Like Dopamine Receptors., Ågren R,Sahlholm K, Front Pharmacol. April 7, 2020; 11:1663-9812.

A System for Assessing Dual Action Modulators of Glycine Transporters and Glycine Receptors., Sheipouri D,Gallagher CI,Shimmon S,Rawling T,Vandenberg RJ, Biomolecules. November 30, 2020; 10(12):2218-273X.

The RNA helicase DDX3 induces neural crest by promoting AKT activity., Perfetto M,Xu X,Lu C,Shi Y,Shi Y,Yousaf N,Li J,Yien YY,Wei S, Development. January 19, 2021; 148(2):1477-9129.

Functional modulation of the human voltage-gated sodium channel NaV1.8 by auxiliary β subunits., Nevin ST,Lawrence N,Nicke A,Lewis RJ,Adams DJ, Channels (Austin). December 1, 2021; 15(1):1933-6969.

MiR-9 and the Midbrain-Hindbrain Boundary: A Showcase for the Limited Functional Conservation and Regulatory Complexity of MicroRNAs., Alwin Prem Anand A,Alvarez-Bolado G,Wizenmann A, Front Cell Dev Biol. January 1, 2020; 8:2296-634X.

Xenopus leads the way: Frogs as a pioneering model to understand the human brain., Exner CRT,Willsey HR, Genesis. February 1, 2021; 59(1-2):1526-968X.

Phosphorylation of a chronic pain mutation in the voltage-gated sodium channel Nav1.7 increases voltage sensitivity., Kerth CM,Hautvast P,Körner J,Lampert A,Meents JE, J Biol Chem. January 1, 2021; 296:1083-351X.

Rab11fip5 regulates telencephalon development via ephrinB1 recycling., Yoon J,Garo J,Lee M,Sun J,Hwang YS,Daar IO, Development. February 2, 2021; 148(3):1477-9129.

Parallel in vivo analysis of large-effect autism genes implicates cortical neurogenesis and estrogen in risk and resilience., Willsey HR,Exner CRT,Xu Y,Xu Y,Everitt A,Sun N,Wang B,Dea J,Schmunk G,Zaltsman Y,Teerikorpi N,Kim A,Anderson AS,Shin D,Seyler M,Nowakowski TJ,Harland RM,Willsey AJ,State MW, Neuron. March 3, 2021; 109(5):0896-6273.

Aquatic models of human ciliary diseases., Corkins ME,Krneta-Stankic V,Kloc M,Miller RK, Genesis. February 1, 2021; 59(1-2):1526-968X.

Biallelic variants in COPB1 cause a novel, severe intellectual disability syndrome with cataracts and variable microcephaly., Macken WL,Godwin A,Wheway G,Stals K,Nazlamova L,Ellard S,Alfares A,Aloraini T,AlSubaie L,Alfadhel M,Alajaji S,Wai HA,Self J,Douglas AGL,Kao AP,Guille M,Baralle D, Genome Med. February 25, 2021; 13(1):1756-994X.

Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis., Pizzo L,Lasser M,Yusuff T,Jensen M,Ingraham P,Huber E,Singh MD,Monahan C,Iyer J,Desai I,Karthikeyan S,Gould DJ,Yennawar S,Weiner AT,Pounraja VK,Krishnan A,Rolls MM,Lowery LA,Girirajan S, PLoS Genet. April 5, 2021; 17(4):1553-7404.

Dissecting the Molecular Determinants of GABAA Receptors Current Rundown, a Hallmark of Refractory Human Epilepsy., Cifelli P,Di Angelantonio S,Alfano V,Morano A,De Felice E,Aronica E,Ruffolo G,Palma E, Brain Sci. March 30, 2021; 11(4):2076-3425.

Bioelectric signaling: Reprogrammable circuits underlying embryogenesis, regeneration, and cancer., Levin M, Cell. April 15, 2021; :1097-4172.

Local Anesthetics Inhibit Transient Receptor Potential Vanilloid Subtype 3 Channel Function in Xenopus Oocytes., Horishita R,Ogata Y,Fukui R,Yamazaki R,Moriwaki K,Ueno S,Yanagihara N,Uezono Y,Yokoyama Y,Minami K,Horishita T, Anesth Analg. June 1, 2021; 132(6):1526-7598.

WIN55,212-2, a Dual Modulator of Cannabinoid Receptors and G Protein-Coupled Inward Rectifier Potassium Channels., An D,Peigneur S,Tytgat J, Biomedicines. April 28, 2021; 9(5):2227-9059.

Early Developmental Exposure to Fluoxetine and Citalopram Results in Different Neurodevelopmental Outcomes., Liu K,Garcia A,Park JJ,Toliver AA,Ramos L,Aizenman CD, Neuroscience. July 15, 2021; 467:1873-7544.

Role of matrix metalloproteinase-9 in neurodevelopmental deficits and experience-dependent plasticity in Xenopus laevis., Gore SV,James EJ,Huang LC,Park JJ,Berghella A,Thompson AC,Cline HT,Aizenman CD, Elife. July 20, 2021; 10:2050-084X.

A convergent molecular network underlying autism and congenital heart disease., Rosenthal SB,Willsey HR,Xu Y,Xu Y,Mei Y,Dea J,Wang S,Curtis C,Sempou E,Khokha MK,Chi NC,Willsey AJ,Fisch KM,Ideker T, Cell Syst. November 17, 2021; 12(11):2405-4720.

A role for zinc transporter gene SLC39A12 in the nervous system and beyond., Davis DN,Strong MD,Chambers E,Hart MD,Bettaieb A,Clarke SL,Smith BJ,Stoecker BJ,Lucas EA,Lin D,Chowanadisai W, Gene. October 5, 2021; 799:1879-0038.

KCNK18 Biallelic Variants Associated with Intellectual Disability and Neurodevelopmental Disorders Alter TRESK Channel Activity., Pavinato L,Nematian-Ardestani E,Zonta A,De Rubeis S,Buxbaum J,Mancini C,Bruselles A,Tartaglia M,Pessia M,Tucker SJ,D'Adamo MC,Brusco A, Int J Mol Sci. June 4, 2021; 22(11):1422-0067.

Molecular Regulation of Betulinic Acid on α3β4 Nicotinic Acetylcholine Receptors., Lee S,Jung W,Eom S,Yeom HD,Park HD,Lee JH,Lee JH, Molecules. May 1, 2021; 26(9):1420-3049.

Stable desensitization of α7 nicotinic acetylcholine receptors by NS6740 requires interaction with S36 in the orthosteric agonist binding site., Pismataro MC,Horenstein NA,Stokes C,Dallanoce C,Thakur GA,Papke RL, Eur J Pharmacol. August 15, 2021; 905:1879-0712.

Transport rate of EAAT2 is regulated by amino acid located at the interface between the scaffolding and substrate transport domains., Duffield M,Patel A,Mortensen OV,Schnur D,Gonzalez-Suarez AD,Torres-Salazar D,Fontana ACK, Neurochem Int. October 1, 2020; 139:1872-9754.

Discovery of Dihydropyrrolo[1,2-a]pyrazin-3(4H)-one-Based Second-Generation GluN2C- and GluN2D-Selective Positive Allosteric Modulators (PAMs) of the N-Methyl-d-Aspartate (NMDA) Receptor., Epplin MP,Mohan A,Harris LD,Zhu Z,Strong KL,Bacsa J,Le P,Menaldino DS,Traynelis SF,Liotta DC, J Med Chem. July 23, 2020; 63(14):1520-4804.

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A novel SMARCC1 BAFopathy implicates neural progenitor epigenetic dysregulation in human hydrocephalus., Singh AK,Allington G,Viviano S,McGee S,Kiziltug E,Ma S,Zhao S,Mekbib KY,Shohfi JP,Duy PQ,DeSpenza T,Furey CG,Reeves BC,Smith H,Sousa AMM,Cherskov A,Allocco A,Nelson-Williams C,Haider S,Rizvi SRA,Alper SL,Sestan N,Shimelis H,Walsh LK,Lifton RP,Moreno-De-Luca A,Jin SC,Kruszka P,Deniz E,Kahle KT, Brain. December 21, 2023; :1460-2156.