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XB-GRNA-25875083
gRNA Name:
lrp2 gRNA1
Synonyms:
Genomic Target: lrp2
PAM Sequence: GGG
Sequence: 5' GCATAGGGAATGTGGTCCGG 3'
Synonyms:
Genomic Target: lrp2
PAM Sequence: GGG
Sequence: 5' GCATAGGGAATGTGGTCCGG 3'
Genomic Target | tropicalis | laevis.L | |||||
Identities | 20/20 | 20/20 | |||||
genome
gRNA
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5' CCGGACCACATTCCCTATGC 3' |||||||||||||||||||| 3' GGCCTGGTGTAAGGGATACG 5' |
5' CCGGACCACATTCCCTATGC 3' |||||||||||||||||||| 3' GGCCTGGTGTAAGGGATACG 5' |
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Genomic Alignments | Position | Identity | Strand | Target | Genomic Target | ||
laevis 10.1 | Chr9_10L:75069293..75069312 | 20/20 | Antisense | target | lrp2.L | ||
Chr9_10S:3575874..3575893 | 18/20 | Antisense | off-target | stk4.S | |||
Chr6S:26072561..26072580 | 18/20 | Antisense | off-target | ppp1r9a.S | |||
Chr9_10L:78547348..78547367 | 16/20 | Antisense | off-target | hoxd10.L | |||
Chr9_10L:78547348..78547367 | 16/20 | Antisense | off-target | LOC121397930 | |||
Chr9_10L:129143452..129143471 | 16/20 | Antisense | off-target | LOC121398222 | |||
Chr9_10L:128207878..128207897 | 17/20 | Antisense | unknown | tropicalis 10.0 | Chr9:68763296..68763315 | 20/20 | Sense | target | lrp2 |
Chr3:91010310..91010329 | 18/20 | Sense | off-target | acsbg1 | |||
Chr9:64999703..64999722 | 16/20 | Sense | off-target | LOC116406456 | |||
Publications | |||||||
???morpholino.displaySummary.papersFirst??? |
Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds., Development 2021 |
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???morpholino.displaySummary.papersRecent??? | |||||||
???morpholino.displaySummary.papersAll??? |