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XB-GRNA-23659085
gRNA Name:
tbx4 gRNA2
Synonyms: tbx4_gRNA2
Genomic Target: tbx4
Sequence: 5' TGATGACAGTGACCTCCGTGTGG 3'
Synonyms: tbx4_gRNA2
Genomic Target: tbx4
Sequence: 5' TGATGACAGTGACCTCCGTGTGG 3'
Genomic Target | tropicalis | laevis.L | laevis.S | ||||
Identities | 23/23 | 22/23 | 23/23 | ||||
genome
gRNA
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5' CCACACGGAGGTCACTGTCATCA 3' ||||||||||||||||||||||| 3' GGTGTGCCTCCAGTGACAGTAGT 5' |
5' CTACACGGAGGTCACTGTCATCA 3'
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3' GGTGTGCCTCCAGTGACAGTAGT 5' |
5' CCACACGGAGGTCACTGTCATCA 3' ||||||||||||||||||||||| 3' GGTGTGCCTCCAGTGACAGTAGT 5' |
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Genomic Alignments | Position | Identity | Strand | Target | Genomic Target | ||
laevis 9.2 | chr2S:75447814..75447836 | 23/23 | Antisense | target | tbx4.S | ||
chr2L:90038055..90038077 | 22/23 | Antisense | target | tbx4.L | |||
chr5L:3660107..3660129 | 19/23 | Sense | unknown | tropicalis 10.0 | Chr2:92048341..92048363 | 23/23 | Antisense | target | tbx4 |
Chr5:112453207..112453229 | 19/23 | Sense | off-target | mecom | |||
Publications | |||||||
???morpholino.displaySummary.papersFirst??? |
Homozygous Null TBX4 Mutations Lead to Posterior Amelia with Pelvic and Pulmonary Hypoplasia., Am J Hum Genet 2019 |
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???morpholino.displaySummary.papersRecent??? | |||||||
???morpholino.displaySummary.papersAll??? |