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Summary Attributions Wiki
XB-MORPHOLINO-22249065

Morpholino Name: fbrsl1 MO1
Synonyms: fbrsl1 E1/I1
Target mRNA: fbrsl1

Morpholino Type: splice blocking morpholino (E1-I1)
Sequence: 5' ATAACTCTCTCTTACCTCTAAGGCT 3'

Source: Gene Tools LLC


Target mRNA tropicalis
Identities 24/25
genome
MO
 
5' AGCCTTAGAGGTAAGAAAGAGTTAT 3'
   |||||||||||||||| ||||||||
3' TCGGAATCTCCATTCTCTCTCAATA 5'
      
Genomic Alignments Position Identity Strand Target Target mRNA
laevis 10.1 Chr1L:169236978..169237002 25/25 Sense off-target LOC108716118
Chr1S:144612882..144612906 24/25 Sense off-target LOC108707141
Chr8L:51239730..51239754 21/25 Antisense off-target kiaa1210.L
Chr1S:119764056..119764080 21/25 Sense off-target LOC121399438
Chr1S:116486625..116486649 21/25 Antisense unknown
Chr1S:116606854..116606878 21/25 Antisense unknown
Chr1S:116650759..116650783 21/25 Antisense unknown
Chr1S:116730629..116730653 21/25 Antisense unknown
Chr1S:116832198..116832222 21/25 Antisense unknown
Chr1S:116879346..116879370 21/25 Antisense unknown
Chr1S:117249168..117249192 21/25 Sense unknown
Chr1S:117286066..117286090 21/25 Sense unknown
Chr1S:118491952..118491976 21/25 Antisense unknown
Chr6L:53567307..53567331 21/25 Antisense unknown
tropicalis 10.0 Chr1:155866727..155866751 24/25 Sense target fbrsl1
Chr2:122318038..122318062 21/25 Antisense off-target dnajc3
Chr8:85975326..85975350 21/25 Antisense off-target zc3h14
Chr3:112292850..112292874 21/25 Sense off-target st8sia2
Chr5:49987935..49987959 21/25 Antisense unknown
Publications
???morpholino.displaySummary.papersFirst??? De novo mutations in FBRSL1 cause a novel recognizable malformation and intellectual disability syndrome., Hum Genet 2020     
???morpholino.displaySummary.papersRecent??? Fbrsl1 is required for heart development in Xenopus laevis and de novo variants in FBRSL1 can cause human heart defects., Dis Model Mech 2024     
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