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XB-ANTIBODY-23622609
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Antibody Name:
Casp3.2 Ab10
Common Name: cleaved caspase-3 RRID: AB_2341188 Synonyms: 9661, apoptain, Caspase-3, cpp-21
Source: Cell Signaling Technology |
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| Antibody | |
| Clone Number | |
| Purification | |
| Isotype | isotype unknown |
| Host Organism | rabbit |
| Xenopus Reactivity | X. laevis |
| Non-Xenopus Reactivity | human, monkey, mouse, rat |
| Description: | Cleaved Caspase-3 (Asp175) Antibody detects endogenous levels of the large fragment (17/19 kDa) of activated caspase-3 resulting from cleavage adjacent to Asp175. This antibody does not recognize full length caspase-3 or other cleaved caspases. Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires the aspartic acid residue at the P1 position (2). Citation:(Cell Signaling Technology Cat# 9661, RRID:AB_2341188) |
| Immunogen | |
| Name | casp3.2 |
| Type | polypeptide |
| Post Translational Modifications | None |
| Source Organism | frog |
| Description | Cleaved Caspase-3 (Asp175) Antibody detects endogenous levels of the large fragment (17/19 kDa) of activated caspase-3 resulting from cleavage adjacent to Asp175. This antibody does not recognize full length caspase-3 or other cleaved caspases. |
| Sequence | |
| Reported Usage | |
| Publications | |
| First: |
Bisphenol A exposure induces apoptosis and impairs early embryonic development in Xenopus laevis., Environ Pollut 2021 |
| Most recent: |
Developmental regulation of cellular metabolism is required for intestinal elongation and rotation., Development 2024  |
| View All Papers | |
