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Summary Images Attributions Wiki Source

Antibody Name: Lrp6 Ab1

Common Name: anti-Phospho-LRP6

Synonyms: 2568

Gene: lrp6

Clone Type: Polyclonal
Source: Cell Signaling Technology

Clone Number
Purification Affinity Purification
Isotype isotype unknown
Host Organism rabbit
Xenopus Reactivity X. tropicalis, X. laevis
Non-Xenopus Reactivity human, mouse
Description: Supplied by Cell technology CAT#2568.
Name lrp6
Type synthetic sequence
Post Translational Modifications Phosphorylated
Source Organism frog
Description Phospho-LRP6 (Ser1490) Antibody detects endogenous levels of LRP6 protein when phosphorylated at serine 1490. It is expected, although not yet confirmed, to also detect endogenous levels of LRP5 protein when phosphorylated at serine 1493 (corresponding to serine 1490 in LRP6). Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser1490 of human LRP6.
Reported Usage
western blot 1:1000 dilution
First: Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation., Dev Cell 2015                                    
Most recent: Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover., Dev Cell 2017                                  
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