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Summary Images Attributions Wiki Source
XB-ANTIBODY-14575286

Antibody Name: Neuronal Ab4

Common Name: Neurofilament

RRID: AB_531874
Synonyms: 3A10, NAA
Antigens
XAO: spinal cord, central nervous system, retinal ganglion cell, Mauthner cell
GO: neurofilament
Clone Type: Monoclonal
Source: Developmental Studies Hybridoma Bank
1/2

Antibody
Clone Number 3A10
Purification
Isotype IgG1
Host Organism mouse
Xenopus Reactivity X. laevis
Non-Xenopus Reactivity chicken, mouse, rat, zebrafish
Description: This antibody recognizes a neurofilament-associated antigen. The antibody labels a subset of hindbrain spinal cord projecting neurons such as Mauthner neurons. 3A10 recognizes a conformational epitope associated with the TRSPXP sequence that is shared by neurofilament-associated antigens in the developing rat brain. Also known as NAA = neurofilament associated antigen. 3A10 was deposited to the DSHB by Jessell, T.M.,Dodd, J. and Brenner-Morton, S. Citation:(DSHB Cat# 3A10, RRID:AB_531874).
Immunogen
Name NAA - neurofilament assoc antigen
Type polypeptide
Post Translational Modifications None
Source Organism chicken
Description Chick nervous tissue from ventral spinal cord/cyclophosphamide treatment/assorted nervous tissue
Sequence
Reported Usage
immunohistochemistry 1:100-1:1000
Publications
???displayAntibody.papersFirst??? Axon guidance and the patterning of neuronal projections in vertebrates., Science 1988  
???displayAntibody.papersRecent??? Prdm15 acts upstream of Wnt4 signaling in anterior neural development of Xenopus laevis., Front Cell Dev Biol 2024                              
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