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XB-ANTIBODY-14575286

Antibody Name: Neuronal Ab4

Common Name: Neurofilament

RRID: AB_531874
Synonyms: 3A10, NAA
Antigens
XAO: spinal cord, central nervous system, retinal ganglion cell, Mauthner cell
GO: neurofilament
Clone Type: Monoclonal
Source: Developmental Studies Hybridoma Bank
1/2

Antibody
Clone Number 3A10
Purification
Isotype IgG1
Host Organism mouse
Xenopus Reactivity X. laevis
Non-Xenopus Reactivity chicken, mouse, rat, zebrafish
Description: This antibody recognizes a neurofilament-associated antigen. The antibody labels a subset of hindbrain spinal cord projecting neurons such as Mauthner neurons. 3A10 recognizes a conformational epitope associated with the TRSPXP sequence that is shared by neurofilament-associated antigens in the developing rat brain. Also known as NAA = neurofilament associated antigen. 3A10 was deposited to the DSHB by Jessell, T.M.,Dodd, J. and Brenner-Morton, S. Citation:(DSHB Cat# 3A10, RRID:AB_531874).
Immunogen
Name NAA - neurofilament assoc antigen
Type polypeptide
Post Translational Modifications None
Source Organism chicken
Description Chick nervous tissue from ventral spinal cord/cyclophosphamide treatment/assorted nervous tissue
Sequence
Reported Usage
immunohistochemistry 1:100-1:1000
Publications
First: Axon guidance and the patterning of neuronal projections in vertebrates., Science 1988  
Most recent: Postsynaptic and Presynaptic NMDARs Have Distinct Roles in Visual Circuit Development., Cell Rep 2020                                              
View All Papers