Summary Images Attributions Wiki Source

Antibody Name: Cdh1 Ab2 Common Name: E-cadherin RRID: AB_528117 Synonyms: 8C2, cd324, cdhe, ecad Antigens Gene: cdh1 XAO: ectoderm, epithelial cell Clone Type: Monoclonal Source: Developmental Studies Hybridoma Bank

Antibody
Clone Number	8C2
Purification
Isotype	IgG1
Host Organism	mouse
Xenopus Reactivity	X. tropicalis, X. laevis
Non-Xenopus Reactivity	chicken
Description:	Generated by Barry Gumbiner. Supplied by DSHB, Cat# 8C2c Citation: (DSHB Cat# 8c2, RRID:AB_528117). Please email citation to DSHB.
Immunogen
Name	E-cadherin
Type	polypeptide
Post Translational Modifications	None
Source Organism	frog
Description	Purified E-cadherin extracellular domain (100 kDa trypsin fragment ectodomain) from Xenopus A6 kidney cell line. 8C2 only binds the -(Ca++) conformation of E-cadherin. Blocks epithelial cell-cell adhesion and cell junction formation. Stains ectoderm, all epithelia and regions of cell-cell contact. E-cadherin-specific by immunoblotting and immunoprecipitation.
Sequence
Reported Usage
western blot
immunoprecipitation
immunofluorescence
Publications
???displayAntibody.papersFirst???	Expression of cell adhesion molecule E-cadherin in Xenopus embryos begins at gastrulation and predominates in the ectoderm., J Cell Biol 1989
???displayAntibody.papersRecent???	Interaction between SPARC and tubulin in Xenopus., Cell Tissue Res 2004
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