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XB-ANTIBODY-14579519
Antibody Name:
Polr2a Ab4
Common Name: phospho-RNA Pol II RRID: Synonyms: H14, MMS-134R
Source: |
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Antibody | |
Clone Number | H14 |
Purification | Ascites |
Isotype | IgM |
Host Organism | mouse |
Xenopus Reactivity | X. tropicalis |
Non-Xenopus Reactivity | |
Description: | Supplied by Covance, cat# MMS-134R |
Immunogen | |
Name | RNA pol II |
Type | polypeptide |
Post Translational Modifications | Phosphorylated |
Source Organism | frog |
Description | The antibody H14 was developed against a purified phosphorylated form of RNA polymerase II extracted from a transformed cell line. Pol II has two physiologically important phosphorylation sites; ser-2 and ser-5. Both sites are found in the heptapeptide repeat YSPTSPS at the C-terminal domain. This antibody recognizes the phosphoserine 5 version of pol II. |
Sequence | |
Reported Usage | |
immunohistochemistry | Dilution 1:100 |
Publications | |
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Repression of zygotic gene expression in the Xenopus germline., Development 2010 |
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