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Deconstruction of an African folk medicine uncovers a novel molecular strategy for therapeutic potassium channel activation., De Silva AM, Manville RW, Abbott GW., Sci Adv. November 14, 2018; 4 (11): eaav0824.
Development of epithelial tissues: How are cleavage planes chosen?, Xin Y, Karunarathna Mudiyanselage CM, Just W., PLoS One. November 7, 2018; 13 (11): e0205834.
Directional coupling of oligodendrocyte connexin-47 and astrocyte connexin-43 gap junctions., Fasciani I, Pluta P, González-Nieto D, Martínez-Montero P, Molano J, Paíno CL, Millet O, Barrio LC., Glia. November 1, 2018; 66 (11): 2340-2352.
Development of an Acute Method to Deliver Transgenes Into the Brains of Adult Xenopus laevis., Yamaguchi A, Woller DJ, Rodrigues P., Front Neural Circuits. October 26, 2018; 12 92.
Dimerization quality control ensures neuronal development and survival., Mena EL, Kjolby RAS, Saxton RA, Werner A, Lew BG, Boyle JM, Harland R, Rape M., Science. October 12, 2018; 362 (6411):
Dissecting and Culturing Animal Cap Explants., Dingwell KS, Smith JC., Cold Spring Harb Protoc. October 1, 2018; 2018 (10):
Developmental dependence for functional eye regrowth in Xenopus laevis., Kha CX, Tseng KA., Neural Regen Res. October 1, 2018; 13 (10): 1735-1737.
Determinants of selective ion permeation in the epithelial Na+ channel., Yang L, Palmer LG., J Gen Physiol. October 1, 2018; 150 (10): 1397-1407.
DSCAM differentially modulates pre- and postsynaptic structural and functional central connectivity during visual system wiring., Santos RA, Fuertes AJC, Short G, Donohue KC, Shao H, Quintanilla J, Malakzadeh P, Cohen-Cory S., Neural Dev. September 15, 2018; 13 (1): 22.
Discovery of Novel Aminotetralines and Aminochromanes as Selective and Competitive Glycine Transporter 1 (GlyT1) Inhibitors., Amberg W, Lange UEW, Ochse M, Pohlki F, Behl B, Relo AL, Hornberger W, Hoft C, Mezler M, Sydor J, Wang Y, Zhao H, Brewer JT, Dietrich J, Li H, Akritopoulou-Zanze I, Lao Y, Hannick SM, Ku YY, Vasudevan A., J Med Chem. September 13, 2018; 61 (17): 7503-7524.
De Novo Design, Synthesis, and Biological Evaluation of 3,4-Disubstituted Pyrrolidine Sulfonamides as Potent and Selective Glycine Transporter 1 Competitive Inhibitors., Wang Y, Zhao H, Brewer JT, Li H, Lao Y, Amberg W, Behl B, Akritopoulou-Zanze I, Dietrich J, Lange UEW, Pohlki F, Hoft C, Hornberger W, Djuric SW, Sydor J, Mezler M, Relo AL, Vasudevan A., J Med Chem. September 13, 2018; 61 (17): 7486-7502.
Dissecting Protein Complexes in Branching Microtubule Nucleation Using Meiotic Xenopus Egg Extracts., Song JG, Petry S., Cold Spring Harb Protoc. September 4, 2018; 2018 (9):
Dual function model revised by thyroid hormone receptor alpha knockout frogs., Buchholz DR, Shi YB., Gen Comp Endocrinol. September 1, 2018; 265 214-218.
Determination of metals and pharmaceutical compounds released in hospital wastewater from Toluca, Mexico, and evaluation of their toxic impact., Pérez-Alvarez I, Islas-Flores H, Gómez-Oliván LM, Barceló D, López De Alda M, Pérez Solsona S, Sánchez-Aceves L, SanJuan-Reyes N, Galar-Martínez M., Environ Pollut. September 1, 2018; 240 330-341.
Developmental profiles of progesterone receptor transcripts and molecular responses to gestagen exposure during Silurana tropicalis early development., Thomson P, Langlois VS., Gen Comp Endocrinol. September 1, 2018; 265 4-14.
Differential modulation of human GABAC-ρ1 receptor by sulfur-containing compounds structurally related to taurine., Ochoa-de la Paz LD, González-Andrade M, Pasantes-Morales H, Franco R, Zamora-Alvarado R, Zenteno E, Quiroz-Mercado H, Gonzales-Salinas R, Gulias-Cañizo R., BMC Neurosci. August 3, 2018; 19 (1): 47.
Developmental toxicity of dibutyl phthalate and citrate ester plasticizers in Xenopus laevis embryos., Xu Y, Gye MC., Chemosphere. August 1, 2018; 204 523-534.
Design of a New Glutamine-Fipronil Conjugate with α-Amino Acid Function and Its Uptake by A. thaliana Lysine Histidine Transporter 1 ( AtLHT1)., Jiang X, Xie Y, Ren Z, Ganeteg U, Lin F, Zhao C, Xu H., J Agric Food Chem. July 25, 2018; 66 (29): 7597-7605.
Dkk2 promotes neural crest specification by activating Wnt/β-catenin signaling in a GSK3β independent manner., Devotta A, Hong CS, Saint-Jeannet JP., Elife. July 23, 2018; 7
Disruption of Amino Acid Homeostasis by Novel ASCT2 Inhibitors Involves Multiple Targets., Bröer A, Fairweather S, Bröer S., Front Pharmacol. July 19, 2018; 9 785.
Distinguishing Species Using GC Contents in Mixed DNA or RNA Sequences., Karimi K, Wuitchik DM, Oldach MJ, Vize PD., Evol Bioinform Online. July 18, 2018; 14 1176934318788866.
Dual roles for ATP in the regulation of phase separated protein aggregates in Xenopus oocyte nucleoli., Hayes MH, Peuchen EH, Dovichi NJ, Weeks DL., Elife. July 17, 2018; 7
Deglycosylation of Shaker KV channels affects voltage sensing and the open-closed transition., Lopez-Rodriguez A, Holmgren M., J Gen Physiol. July 2, 2018; 150 (7): 1025-1034.
Dishevelled: A masterful conductor of complex Wnt signals., Sharma M, Castro-Piedras I, Simmons GE, Pruitt K., Cell Signal. July 1, 2018; 47 52-64.
Developmental expression profiles and thyroidal regulation of cytokines during metamorphosis in the amphibian Xenopus laevis., Gallant MJ, Hogan NS., Gen Comp Endocrinol. July 1, 2018; 263 62-71.
Decreasing arsenic accumulation in rice by overexpressing OsNIP1;1 and OsNIP3;3 through disrupting arsenite radial transport in roots., Sun SK, Chen Y, Che J, Konishi N, Tang Z, Miller AJ, Ma JF, Zhao FJ., New Phytol. July 1, 2018; 219 (2): 641-653.
De novo assembly and annotation of the Acropora gemmifera transcriptome., Oldach MJ, Vize PD., Mar Genomics. July 1, 2018; 40 9-12.
Differential patterns of inhibition of the sugar transporters GLUT2, GLUT5 and GLUT7 by flavonoids., Gauer JS, Tumova S, Lippiat JD, Kerimi A, Williamson G., Biochem Pharmacol. June 1, 2018; 152 11-20.
Direct neurotransmitter activation of voltage-gated potassium channels., Manville RW, Papanikolaou M, Abbott GW., Nat Commun. May 10, 2018; 9 (1): 1847.
Dimerization of the voltage-sensing phosphatase controls its voltage-sensing and catalytic activity., Rayaprolu V, Royal P, Stengel K, Sandoz G, Kohout SC., J Gen Physiol. May 7, 2018; 150 (5): 683-696.
Deciphering the molecular determinants of cholinergic anthelmintic sensitivity in nematodes: When novel functional validation approaches highlight major differences between the model Caenorhabditis elegans and parasitic species., Blanchard A, Guégnard F, Charvet CL, Crisford A, Courtot E, Sauvé C, Harmache A, Duguet T, O'Connor V, Castagnone-Sereno P, Reaves B, Wolstenholme AJ, Beech RN, Holden-Dye L, Neveu C., PLoS Pathog. May 2, 2018; 14 (5): e1006996.
Dual effects of insect nAChR chaperone RIC-3 on hybrid receptor: Promoting assembly on endoplasmic reticulum but suppressing transport to plasma membrane on Xenopus oocytes., Bao H, Xu X, Liu W, Yu N, Liu Z., Neurochem Int. May 1, 2018; 115 24-30.
Direct intertectal inputs are an integral component of the bilateral sensorimotor circuit for behavior in Xenopus tadpoles., Gambrill AC, Faulkner RL, Cline HT., J Neurophysiol. May 1, 2018; 119 (5): 1947-1961.
Dehydroevodiamine and hortiamine, alkaloids from the traditional Chinese herbal drug Evodia rutaecarpa, are IKr blockers with proarrhythmic effects in vitro and in vivo., Baburin I, Varkevisser R, Schramm A, Saxena P, Beyl S, Szkokan P, Linder T, Stary-Weinzinger A, van der Heyden MAG, Houtman M, Takanari H, Jonsson M, Beekman JHD, Hamburger M, Vos MA, Hering S., Pharmacol Res. May 1, 2018; 131 150-163.
Distinct MHC class I-like interacting invariant T cell lineage at the forefront of mycobacterial immunity uncovered in Xenopus., Edholm ES, Banach M, Hyoe Rhoo K, Pavelka MS, Robert J., Proc Natl Acad Sci U S A. April 24, 2018; 115 (17): E4023-E4031.
Dynamic rearrangement of the intrinsic ligand regulates KCNH potassium channels., Dai G, James ZM, Zagotta WN., J Gen Physiol. April 2, 2018; 150 (4): 625-635.
Delineation of the functional properties and the mechanism of action of AA29504, an allosteric agonist and positive allosteric modulator of GABAA receptors., Olander ER, Madjroh N, Bunch L, Söderhielm PC, Jensen AA., Biochem Pharmacol. April 1, 2018; 150 305-319.
Dicer-2 promotes mRNA activation through cytoplasmic polyadenylation., Coll O, Guitart T, Villalba A, Papin C, Simonelig M, Gebauer F., RNA. April 1, 2018; 24 (4): 529-539.
Developmental changes in spinal neuronal properties, motor network configuration, and neuromodulation at free-swimming stages of Xenopus tadpoles., Currie SP, Sillar KT., J Neurophysiol. March 1, 2018; 119 (3): 786-795.
Divergent Evolutionary Trajectories of Two Young, Homomorphic, and Closely Related Sex Chromosome Systems., Furman BLS, Evans BJ., Genome Biol Evol. March 1, 2018; 10 (3): 742-755.
Direct modification of the 5-HT3 receptor current by some anticancer drugs., Nakamura Y, Ishida Y, Kondo M, Shimada S., Eur J Pharmacol. February 15, 2018; 821 21-28.
Direct Binding between Pre-S1 and TRP-like Domains in TRPP Channels Mediates Gating and Functional Regulation by PIP2., Zheng W, Cai R, Hofmann L, Nesin V, Hu Q, Long W, Fatehi M, Liu X, Hussein S, Kong T, Li J, Light PE, Tang J, Flockerzi V, Tsiokas L, Chen XZ., Cell Rep. February 6, 2018; 22 (6): 1560-1573.
Differentiation-dependent antiviral capacities of amphibian (Xenopus laevis) macrophages., Yaparla A, Popovic M, Grayfer L., J Biol Chem. February 2, 2018; 293 (5): 1736-1744.
De novo and inherited mutations in the X-linked gene CLCN4 are associated with syndromic intellectual disability and behavior and seizure disorders in males and females., Palmer EE, Stuhlmann T, Weinert S, Haan E, Van Esch H, Holvoet M, Boyle J, Leffler M, Raynaud M, Moraine C, van Bokhoven H, Kleefstra T, Kahrizi K, Najmabadi H, Ropers HH, Delgado MR, Sirsi D, Golla S, Sommer A, Pietryga MP, Chung WK, Wynn J, Rohena L, Bernardo E, Hamlin D, Faux BM, Grange DK, Manwaring L, Tolmie J, Joss S, DDD Study, Cobben JM, Duijkers FAM, Goehringer JM, Challman TD, Hennig F, Fischer U, Grimme A, Suckow V, Musante L, Nicholl J, Shaw M, Lodh SP, Niu Z, Rosenfeld JA, Stankiewicz P, Jentsch TJ, Gecz J, Field M, Kalscheuer VM., Mol Psychiatry. February 1, 2018; 23 (2): 222-230.
Differential expression of a fructose receptor gene in honey bee workers according to age and behavioral role., Takada T, Sasaki T, Sato R, Kikuta S, Inoue MN., Arch Insect Biochem Physiol. February 1, 2018; 97 (2):
Design, synthesis, and evaluation of polyamine-memantine hybrids as NMDA channel blockers., Kumamoto T, Nakajima M, Uga R, Ihayazaka N, Kashihara H, Katakawa K, Ishikawa T, Saiki R, Nishimura K, Igarashi K., Bioorg Med Chem. February 1, 2018; 26 (3): 603-608.
Distinct reaction mechanisms for hyaluronan biosynthesis in different kingdoms of life., Blackburn MR, Hubbard C, Kiessling V, Bi Y, Kloss B, Tamm LK, Zimmer J., Glycobiology. February 1, 2018; 28 (2): 108-121.
Diversity of Nicotinic Acetylcholine Receptor Positive Allosteric Modulators Revealed by Mutagenesis and a Revised Structural Model., Newcombe J, Chatzidaki A, Sheppard TD, Topf M, Millar NS., Mol Pharmacol. February 1, 2018; 93 (2): 128-140.
Divergent axial morphogenesis and early shh expression in vertebrate prospective floor plate., Kremnyov S, Henningfeld K, Viebahn C, Tsikolia N., Evodevo. January 31, 2018; 9 4.
Distinct modulation of inactivation by a residue in the pore domain of voltage-gated Na+ channels: mechanistic insights from recent crystal structures., Cervenka R, Lukacs P, Gawali VS, Ke S, Koenig X, Rubi L, Zarrabi T, Hilber K, Sandtner W, Stary-Weinzinger A, Todt H., Sci Rep. January 12, 2018; 8 (1): 631.

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