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Pre-clinical properties of the alpha4beta2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence., Rollema H, Shrikhande A, Ward KM, Tingley FD, Coe JW, O'Neill BT, Tseng E, Wang EQ, Mather RJ, Hurst RS, Williams KE, de Vries M, Cremers T, Bertrand S, Bertrand D., Br J Pharmacol. May 1, 2010; 160 (2): 334-45.


Preparation of Xenopus tropicalis whole chromosome painting probes using laser microdissection and reconstruction of X. laevis tetraploid karyotype by Zoo-FISH., Krylov V, Kubickova S, Rubes J, Macha J, Tlapakova T, Seifertova E, Sebkova N., Chromosome Res. June 1, 2010; 18 (4): 431-9.


Polycystin-1 interacts with inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling with implications for polycystic kidney disease., Li Y, Santoso NG, Woodward OM, Qian F, Guggino WB., J Biol Chem. December 25, 2009; 284 (52): 36431-36441.


Phosphatidylinositol 4,5-bisphosphate activates Slo3 currents and its hydrolysis underlies the epidermal growth factor-induced current inhibition., Tang QY, Zhang Z, Xia J, Ren D, Logothetis DE., J Biol Chem. June 18, 2010; 285 (25): 19259-66.


Polypyrimidine tract-binding protein is required for the repression of gene expression by all-trans retinoic acid., Tamanoue Y, Yamagishi M, Hongo I, Okamoto H., Dev Growth Differ. June 1, 2010; 52 (5): 469-79.   


PIKK-dependent phosphorylation of Mre11 induces MRN complex inactivation by disassembly from chromatin., Di Virgilio M, Ying CY, Gautier J., DNA Repair (Amst). November 2, 2009; 8 (11): 1311-20.


p63 antagonizes Wnt-induced transcription., Drewelus I, Göpfert C, Hippel C, Dickmanns A, Damianitsch K, Pieler T, Dobbelstein M., Cell Cycle. February 1, 2010; 9 (3): 580-87.


Passage through vertebrate gap junctions of 17/18kDa molecules is primarily dependent upon molecular configuration., Cieniewicz AM, Woodruff RI., Tissue Cell. February 1, 2010; 42 (1): 47-52.


Proper organization of microtubule minus ends is needed for midzone stability and cytokinesis., Cai S, Weaver LN, Ems-McClung SC, Walczak CE., Curr Biol. May 11, 2010; 20 (9): 880-5.


Proteomic analysis of blastema formation in regenerating axolotl limbs., Rao N, Jhamb D, Milner DJ, Li B, Song F, Wang M, Voss SR, Palakal M, King MW, Saranjami B, Nye HL, Cameron JA, Stocum DL., BMC Biol. November 30, 2009; 7 83.   


Polyribosome analysis for investigating mRNA translation in Xenopus oocytes, eggs and embryos., Sheets MD, Fritz B, Hartley RS, Zhang Y., Methods. May 1, 2010; 51 (1): 152-6.


Perturbation of Notch/Suppressor of Hairless pathway disturbs migration of primordial germ cells in Xenopus embryo., Morichika K, Kataoka K, Terayama K, Tazaki A, Kinoshita T, Watanabe K, Mochii M., Dev Growth Differ. February 1, 2010; 52 (2): 235-44.


Protein kinase B alpha (PKBα) stimulates the epithelial sodium channel (ENaC) heterologously expressed in Xenopus laevis oocytes by two distinct mechanisms., Diakov A, Nesterov V, Mokrushina M, Rauh R, Korbmacher C., Cell Physiol Biochem. January 1, 2010; 26 (6): 913-24.


Paralysis and delayed Z-disc formation in the Xenopus tropicalis unc45b mutant dicky ticker., Geach TJ, Zimmerman LB., BMC Dev Biol. January 22, 2010; 10 75.   


Probing the (H3-H4)2 histone tetramer structure using pulsed EPR spectroscopy combined with site-directed spin labelling., Bowman A, Ward R, El-Mkami H, Owen-Hughes T, Norman DG., Nucleic Acids Res. January 1, 2010; 38 (2): 695-707.   


Phosphopeptide screen uncovers novel phosphorylation sites of Nedd4-2 that potentiate its inhibition of the epithelial Na+ channel., Hallows KR, Bhalla V, Oyster NM, Wijngaarden MA, Lee JK, Li H, Chandran S, Xia X, Huang Z, Chalkley RJ, Burlingame AL, Pearce D., J Biol Chem. July 9, 2010; 285 (28): 21671-8.


Photoreceptor development in premetamorphic and metamorphic Xenopus laevis., Parker RO, Mccarragher B, Crouch R, Darden AG., Anat Rec (Hoboken). March 1, 2010; 293 (3): 383-7.


Potentiation of the human GABA(A) receptor as a novel mode of action of lower-chlorinated non-dioxin-like PCBs., Fernandes EC, Hendriks HS, van Kleef RG, van den Berg M, Westerink RH., Environ Sci Technol. April 15, 2010; 44 (8): 2864-9.


Proteomic screen for potential regulators of M-phase entry and quality of meiotic resumption in Xenopus laevis oocytes., D'Inca R, Marteil G, Bazile F, Pascal A, Guitton N, Lavigne R, Richard-Parpaillon L, Kubiak JZ., J Proteomics. June 16, 2010; 73 (8): 1542-50.


Proton block of the CLC-5 Cl-/H+ exchanger., Picollo A, Malvezzi M, Accardi A., J Gen Physiol. June 1, 2010; 135 (6): 653-9.   


Proteasome inhibition induces hsp30 and hsp70 gene expression as well as the acquisition of thermotolerance in Xenopus laevis A6 cells., Young JT, Heikkila JJ., Cell Stress Chaperones. May 1, 2010; 15 (3): 323-34.


Pumilio 2 controls translation by competing with eIF4E for 7-methyl guanosine cap recognition., Cao Q, Padmanabhan K, Richter JD., RNA. January 1, 2010; 16 (1): 221-7.


PD-118057 contacts the pore helix of hERG1 channels to attenuate inactivation and enhance K+ conductance., Perry M, Sachse FB, Abbruzzese J, Sanguinetti MC., Proc Natl Acad Sci U S A. November 24, 2009; 106 (47): 20075-80.


PIKfyve upregulates CFTR activity., Gehring EM, Lam RS, Siraskar G, Koutsouki E, Seebohm G, Ureche ON, Ureche L, Baltaev R, Tavare JM, Lang F., Biochem Biophys Res Commun. December 18, 2009; 390 (3): 952-7.


Planar cell polarity enables posterior localization of nodal cilia and left-right axis determination during mouse and Xenopus embryogenesis., Antic D, Stubbs JL, Suyama K, Kintner C, Scott MP, Axelrod JD., PLoS One. February 2, 2010; 5 (2): e8999.   


PfCHA is a mitochondrial divalent cation/H+ antiporter in Plasmodium falciparum., Rotmann A, Sanchez C, Guiguemde A, Rohrbach P, Dave A, Bakouh N, Planelles G, Lanzer M., Mol Microbiol. June 1, 2010; 76 (6): 1591-606.


Potassium channel regulator KCNRG regulates surface expression of Shaker-type potassium channels., Usman H, Mathew MK., Biochem Biophys Res Commun. January 15, 2010; 391 (3): 1301-5.


PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology., McCoy KL, Traynelis SF, Hepler JR., Mol Pharmacol. June 1, 2010; 77 (6): 1005-15.


Planar cell polarity pathway genes and risk for spina bifida., Wen S, Zhu H, Lu W, Mitchell LE, Shaw GM, Lammer EJ, Finnell RH., Am J Med Genet A. February 1, 2010; 152A (2): 299-304.


Plant homologs of the Plasmodium falciparum chloroquine-resistance transporter, PfCRT, are required for glutathione homeostasis and stress responses., Maughan SC, Pasternak M, Cairns N, Kiddle G, Brach T, Jarvis R, Haas F, Nieuwland J, Lim B, Müller C, Salcedo-Sora E, Kruse C, Orsel M, Hell R, Miller AJ, Bray P, Foyer CH, Murray JA, Meyer AJ, Cobbett CS., Proc Natl Acad Sci U S A. February 2, 2010; 107 (5): 2331-6.


PDGF-A interactions with fibronectin reveal a critical role for heparan sulfate in directed cell migration during Xenopus gastrulation., Smith EM, Mitsi M, Nugent MA, Symes K., Proc Natl Acad Sci U S A. December 22, 2009; 106 (51): 21683-8.   


Preparation of a highly active cell-free translation system from immature Xenopus laevis oocytes., Pratt CA, Mowry KL., Methods. May 1, 2010; 51 (1): 101-5.


Pentavalent methylated arsenicals are substrates of human AQP9., McDermott JR, Jiang X, Beene LC, Rosen BP, Liu Z., Biometals. February 1, 2010; 23 (1): 119-27.


Phylotypic expression of the bHLH genes Neurogenin2, Neurod, and Mash1 in the mouse embryonic forebrain., Osório J, Mueller T, Rétaux S, Vernier P, Wullimann MF., J Comp Neurol. March 15, 2010; 518 (6): 851-71.


PIASy mediates SUMO-2/3 conjugation of poly(ADP-ribose) polymerase 1 (PARP1) on mitotic chromosomes., Ryu H, Al-Ani G, Deckert K, Kirkpatrick D, Gygi SP, Dasso M, Azuma Y., J Biol Chem. May 7, 2010; 285 (19): 14415-23.


PRDC regulates placode neurogenesis in chick by modulating BMP signalling., Kriebitz NN, Kiecker C, McCormick L, Lumsden A, Graham A, Bell E., Dev Biol. December 15, 2009; 336 (2): 280-92.   


Peptide sr11a from Conus spurius is a novel peptide blocker for Kv1 potassium channels., Aguilar MB, Pérez-Reyes LI, López Z, de la Cotera EP, Falcón A, Ayala C, Galván M, Salvador C, Escobar LI., Peptides. July 1, 2010; 31 (7): 1287-91.


Polypyrimidine tract binding protein prevents activity of an intronic regulatory element that promotes usage of a composite 3'-terminal exon., Anquetil V, Le Sommer C, Méreau A, Hamon S, Lerivray H, Hardy S., J Biol Chem. November 20, 2009; 284 (47): 32370-83.


Peptidyl-prolyl isomerase FKBP52 controls chemotropic guidance of neuronal growth cones via regulation of TRPC1 channel opening., Shim S, Yuan JP, Kim JY, Zeng W, Huang G, Milshteyn A, Kern D, Muallem S, Ming GL, Worley PF., Neuron. November 25, 2009; 64 (4): 471-83.


p27(BBP)/eIF6 acts as an anti-apoptotic factor upstream of Bcl-2 during Xenopus laevis development., De Marco N, Iannone L, Carotenuto R, Biffo S, Vitale A, Campanella C., Cell Death Differ. February 1, 2010; 17 (2): 360-72.


Pressure, the nervous system and ion channels: are humans too complicated?, Friedrich O., Undersea Hyperb Med. January 1, 2010; 37 (5): 241-4.


PKA and PKC partially rescue long QT type 1 phenotype by restoring channel-PIP2 interactions., Matavel A, Medei E, Lopes CM., Channels (Austin). January 1, 2010; 4 (1): 3-11.


Position 552 in a FMRFamide-gated Na(+) channel affects the gating properties and the potency of FMRFamide., Kodani Y, Furukawa Y., Zoolog Sci. May 1, 2010; 27 (5): 440-8.


Preparation of fixed Xenopus embryos for confocal imaging., Wallingford JB., Cold Spring Harb Protoc. May 1, 2010; 2010 (5): pdb.prot5426.


Perspective on the metazoan nuclear pore complex., Maimon T, Medalia O., Nucleus. January 1, 2010; 1 (5): 383-6.


Pharmacological characterization of a novel positive modulator at alpha 4 beta 3 delta-containing extrasynaptic GABA(A) receptors., Hoestgaard-Jensen K, Dalby NO, Wolinsky TD, Murphey C, Jones KA, Rottländer M, Frederiksen K, Watson WP, Jensen K, Ebert B., Neuropharmacology. January 1, 2010; 58 (4-5): 702-11.


Plasma membrane expression of gonadotropin-releasing hormone receptors: regulation by peptide and nonpeptide antagonists., Finch AR, Caunt CJ, Armstrong SP, McArdle CA., Mol Endocrinol. February 1, 2010; 24 (2): 423-35.


Pannexin 1 contributes to ATP release in airway epithelia., Ransford GA, Fregien N, Qiu F, Dahl G, Conner GE, Salathe M., Am J Respir Cell Mol Biol. November 1, 2009; 41 (5): 525-34.


Protective effect of apricot (Prunus armeniaca L.) on hepatic steatosis and damage induced by carbon tetrachloride in Wistar rats., Ozturk F, Gul M, Ates B, Ozturk IC, Cetin A, Vardi N, Otlu A, Yilmaz I., Br J Nutr. December 1, 2009; 102 (12): 1767-75.


Prenylation has a compound specific effect on the estrogenicity of naringenin and genistein., Kretzschmar G, Zierau O, Wober J, Tischer S, Metz P, Vollmer G., J Steroid Biochem Mol Biol. January 1, 2010; 118 (1-2): 1-6.

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