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Thiodipeptides targeting the intestinal oligopeptide transporter as a general approach to improving oral drug delivery., Foley DW, Pathak RB, Phillips TR, Wilson GL, Bailey PD, Pieri M, Senan A, Meredith D., Eur J Med Chem. August 5, 2018; 156 180-189.
The role of pparγ in embryonic development of Xenopus tropicalis under triphenyltin-induced teratogenicity., Zhu J, Huang X, Jiang H, Hu L, Michal JJ, Jiang Z, Shi H., Sci Total Environ. August 15, 2018; 633 1245-1252.
Trypanosoma brucei aquaglyceroporins mediate the transport of metabolic end-products: Methylglyoxal, D-lactate, L-lactate and acetate., Uzcátegui NL, Figarella K, Segnini A, Marsiccobetre S, Lang F, Beitz E, Rodríguez-Acosta A, Bertl A., Biochim Biophys Acta Biomembr. November 1, 2018; 1860 (11): 2252-2261.
The small molecule AMBMP disrupts microtubule growth, ciliogenesis, cell polarity, and cell migration., Werner M, Del Castillo U, Ventrella R, Brotslaw E, Mitchell B., Cytoskeleton (Hoboken). October 1, 2018; 75 (10): 450-457.
Type II Kinase Inhibitors Targeting Cys-Gatekeeper Kinases Display Orthogonality with Wild Type and Ala/Gly-Gatekeeper Kinases., Ocasio CA, Warkentin AA, McIntyre PJ, Barkovich KJ, Vesely C, Spencer J, Shokat KM, Bayliss R., ACS Chem Biol. October 19, 2018; 13 (10): 2956-2965.
The N terminus of α-ENaC mediates ENaC cleavage and activation by furin., Kota P, Gentzsch M, Dang YL, Boucher RC, Stutts MJ., J Gen Physiol. July 6, 2018; 150 (8): 1179-1187.
The development of the human notochord., de Bree K, de Bakker BS, Oostra RJ., PLoS One. October 22, 2018; 13 (10): e0205752.
The evolutionary conserved FOXJ1 target gene Fam183b is essential for motile cilia in Xenopus but dispensable for ciliary function in mice., Beckers A, Ott T, Schuster-Gossler K, Boldt K, Alten L, Ueffing M, Blum M, Gossler A., Sci Rep. October 2, 2018; 8 (1): 14678.
The Lhx1-Ldb1 complex interacts with Furry to regulate microRNA expression during pronephric kidney development., Espiritu EB, Crunk AE, Bais A, Hochbaum D, Cervino AS, Phua YL, Butterworth MB, Goto T, Ho J, Hukriede NA, Cirio MC., Sci Rep. October 30, 2018; 8 (1): 16029.
The publications of embryologist Lev V. Beloussov., Gordon R., Biosystems. November 1, 2018; 173 4-6.
The Calcium-Sensing Receptor Increases Activity of the Renal NCC through the WNK4-SPAK Pathway., Bazúa-Valenti S, Rojas-Vega L, Castañeda-Bueno M, Barrera-Chimal J, Bautista R, Cervantes-Pérez LG, Vázquez N, Plata C, Murillo-de-Ozores AR, González-Mariscal L, Ellison DH, Riccardi D, Bobadilla NA, Gamba G., J Am Soc Nephrol. July 1, 2018; 29 (7): 1838-1848.
The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders., Willsey AJ, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA, Srivastava D, Davis GW, Doudna J, Chang E, Sohal V, Lowenstein DH, Li H, Agard D, Keiser MJ, Shoichet B, von Zastrow M, Mucke L, Finkbeiner S, Gan L, Sestan N, Ward ME, Huttenhain R, Nowakowski TJ, Bellen HJ, Frank LM, Khokha MK, Lifton RP, Kampmann M, Ideker T, State MW, Krogan NJ., Cell. July 26, 2018; 174 (3): 505-520.
The dynamics of gene expression in vertebrate embryogenesis at single-cell resolution., Briggs JA, Weinreb C, Wagner DE, Megason S, Peshkin L, Kirschner MW, Klein AM., Science. June 1, 2018; 360 (6392):
Transcriptomics of dorso-ventral axis determination in Xenopus tropicalis., Monteiro RS, Gentsch GE, Smith JC., Dev Biol. July 15, 2018; 439 (2): 69-79.
The Conorfamide RPRFa Stabilizes the Open Conformation of Acid-Sensing Ion Channel 3 via the Nonproton Ligand-Sensing Domain., Reiners M, Margreiter MA, Oslender-Bujotzek A, Rossetti G, Gründer S, Schmidt A., Mol Pharmacol. October 16, 2018; 94 (4): 1114-1124.
The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function., Silbernagel N, Walecki M, Schäfer MK, Kessler M, Zobeiri M, Rinné S, Kiper AK, Komadowski MA, Vowinkel KS, Wemhöner K, Fortmüller L, Schewe M, Dolga AM, Scekic-Zahirovic J, Matschke LA, Culmsee C, Baukrowitz T, Monassier L, Ullrich ND, Dupuis L, Just S, Budde T, Fabritz L, Decher N., FASEB J. November 1, 2018; 32 (11): 6159-6173.
The left-right asymmetry of liver lobation is generated by Pitx2c-mediated asymmetries in the hepatic diverticulum., Womble M, Amin NM, Nascone-Yoder N., Dev Biol. July 15, 2018; 439 (2): 80-91.
The permeation mechanism of organic cations through a CNG mimic channel., Napolitano LMR, Marchesi A, Rodriguez A, De March M, Onesti S, Laio A, Torre V., PLoS Comput Biol. August 1, 2018; 14 (8): e1006295.
TMEM88 mediates inflammatory cytokines secretion by regulating JNK/P38 and canonical Wnt/β-catenin signaling pathway in LX-2 cells., Xu T, Pan LX, Ge YX, Li P, Meng XM, Huang C, Li J., Inflammopharmacology. October 1, 2018; 26 (5): 1339-1348.
The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis, a tick vector of Lyme disease., Furutani S, Ihara M, Lees K, Buckingham SD, Partridge FA, David JA, Patel R, Warchal S, Mellor IR, Matsuda K, Sattelle DB., Int J Parasitol Drugs Drug Resist. August 1, 2018; 8 (2): 350-360.
TGF-β Family Signaling in Early Vertebrate Development., Zinski J, Tajer B, Mullins MC., Cold Spring Harb Perspect Biol. June 1, 2018; 10 (6):
The nucleoside-diphosphate kinase NME3 associates with nephronophthisis proteins and is required for ciliary function during renal development., Hoff S, Epting D, Falk N, Schroda S, Braun DA, Halbritter J, Hildebrandt F, Kramer-Zucker A, Bergmann C, Walz G, Lienkamp SS., J Biol Chem. September 28, 2018; 293 (39): 15243-15255.
The electrostatic role of the Zn-Cys2His2 complex in binding of operator DNA with transcription factors: mouse EGR-1 from the Cys2His2 family., Chirgadze YN, Boshkova EA, Polozov RV, Sivozhelezov VS, Dzyabchenko AV, Kuzminsky MB, Stepanenko VA, Ivanov VV., J Biomol Struct Dyn. November 1, 2018; 36 (15): 3902-3915.
The proteoglycan-like domain of carbonic anhydrase IX mediates non-catalytic facilitation of lactate transport in cancer cells., Ames S, Pastorekova S, Becker HM., Oncotarget. June 15, 2018; 9 (46): 27940-27957.
The age-regulated zinc finger factor ZNF367 is a new modulator of neuroblast proliferation during embryonic neurogenesis., Naef V, Monticelli S, Corsinovi D, Mazzetto MT, Cellerino A, Ori M., Sci Rep. August 7, 2018; 8 (1): 11836.
TRRAP is a central regulator of human multiciliated cell formation., Wang Z, Plasschaert LW, Aryal S, Renaud NA, Yang Z, Choo-Wing R, Pessotti AD, Kirkpatrick ND, Cochran NR, Carbone W, Maher R, Lindeman A, Russ C, Reece-Hoyes J, McAllister G, Hoffman GR, Roma G, Jaffe AB., J Cell Biol. June 4, 2018; 217 (6): 1941-1955.
Tbx2 is required for the suppression of mesendoderm during early Xenopus development., Teegala S, Chauhan R, Lei E, Weinstein DC., Dev Dyn. July 1, 2018; 247 (7): 903-913.
The cytoskeletal protein Zyxin interacts with the zinc-finger transcription factor Zic1 and plays the role of a scaffold for Gli1 and Zic1 interactions during early development of Xenopus laevis., Martynova NY, Parshina EA, Ermolina LV, Zaraisky AG., Biochem Biophys Res Commun. September 26, 2018; 504 (1): 251-256.
The TMEM16A channel mediates the fast polyspermy block in Xenopus laevis., Wozniak KL, Phelps WA, Tembo M, Lee MT, Carlson AE., J Gen Physiol. September 3, 2018; 150 (9): 1249-1259.
Triheteromeric GluN1/GluN2A/GluN2C NMDARs with Unique Single-Channel Properties Are the Dominant Receptor Population in Cerebellar Granule Cells., Bhattacharya S, Khatri A, Swanger SA, DiRaddo JO, Yi F, Hansen KB, Yuan H, Traynelis SF., Neuron. June 25, 2018; 99 (2): 315-328.e5.
Temporal Regulation of ESCO2 Degradation by the MCM Complex, the CUL4-DDB1-VPRBP Complex, and the Anaphase-Promoting Complex., Minamino M, Tei S, Negishi L, Kanemaki MT, Yoshimura A, Sutani T, Bando M, Shirahige K., Curr Biol. August 20, 2018; 28 (16): 2665-2672.e5.
Two mutations at different positions in the CNBH domain of the hERG channel accelerate deactivation and impair the interaction with the EAG domain., Kume S, Shimomura T, Tateyama M, Kubo Y., J Physiol. October 1, 2018; 596 (19): 4629-4650.
The Xenopus tadpole: An in vivo model to screen drugs favoring remyelination., Mannioui A, Vauzanges Q, Fini JB, Henriet E, Sekizar S, Azoyan L, Thomas JL, Pasquier DD, Giovannangeli C, Demeneix B, Lubetzki C, Zalc B., Mult Scler. October 1, 2018; 24 (11): 1421-1432.
Thyroid hormones and androgens differentially regulate gene expression in testes and ovaries of sexually mature Silurana tropicalis., Campbell DEK, Langlois VS., Gen Comp Endocrinol. October 1, 2018; 267 172-182.
The roles of aromatic residues in the glycine receptor transmembrane domain., Tang B, Lummis SCR., BMC Neurosci. September 6, 2018; 19 (1): 53.
Tectal CRFR1 receptors modulate food intake and feeding behavior in the South African clawed frog Xenopus laevis., Prater CM, Harris BN, Carr JA., Horm Behav. September 1, 2018; 105 86-94.
The fast block to polyspermy: New insight into a century-old problem., Jaffe LA., J Gen Physiol. September 3, 2018; 150 (9): 1233-1234.
Temporal Relationship of Ocular and Tail Segmental Movements Underlying Locomotor-Induced Gaze Stabilization During Undulatory Swimming in Larval Xenopus., Bacqué-Cazenave J, Courtand G, Beraneck M, Lambert FM, Combes D., Front Neural Circuits. October 26, 2018; 12 95.
The multimodal antidepressant vortioxetine may facilitate pyramidal cell firing by inhibition of 5-HT3 receptor expressing interneurons: An in vitro study in rat hippocampus slices., Dale E, Grunnet M, Pehrson AL, Frederiksen K, Larsen PH, Nielsen J, Stensbøl TB, Ebert B, Yin H, Lu D, Liu H, Jensen TN, Yang CR, Sanchez C., Brain Res. June 15, 2018; 1689 1-11.
TBC1d24-ephrinB2 interaction regulates contact inhibition of locomotion in neural crest cell migration., Yoon J, Hwang YS, Lee M, Sun J, Cho HJ, Knapik L, Daar IO., Nat Commun. August 28, 2018; 9 (1): 3491.
The degenerin region of the human bile acid-sensitive ion channel (BASIC) is involved in channel inhibition by calcium and activation by bile acids., Ilyaskin AV, Kirsch SA, Böckmann RA, Sticht H, Korbmacher C, Haerteis S, Diakov A., Pflugers Arch. July 1, 2018; 470 (7): 1087-1102.
The atypical mitogen-activated protein kinase ERK3 is essential for establishment of epithelial architecture., Takahashi C, Miyatake K, Kusakabe M, Nishida E., J Biol Chem. June 1, 2018; 293 (22): 8342-8361.
The b-HLH transcription factor Hes3 participates in neural plate border formation by interfering with Wnt/β-catenin signaling., Hong CS, Saint-Jeannet JP., Dev Biol. October 1, 2018; 442 (1): 162-172.
Transplantation of Ears Provides Insights into Inner Ear Afferent Pathfinding Properties., Gordy C, Straka H, Houston DW, Fritzsch B, Elliott KL., Dev Neurobiol. November 1, 2018; 78 (11): 1064-1080.
The RNA-binding complex ESCRT-II in Xenopus laevis eggs recognizes purine-rich sequences through its subunit, Vps25., Emerman AB, Blower MD., J Biol Chem. August 10, 2018; 293 (32): 12593-12605.
The Xenopus animal cap transcriptome: building a mucociliary epithelium., Angerilli A, Smialowski P, Rupp RA., Nucleic Acids Res. September 28, 2018; 46 (17): 8772-8787.
Tight junction-associated protein GEF-H1 in the neighbours of dividing epithelial cells is essential for adaptation of cell-cell membrane during cytokinesis., Hatte G, Prigent C, Tassan JP., Exp Cell Res. October 1, 2018; 371 (1): 72-82.
The epithelial Na+ channel γ subunit autoinhibitory tract suppresses channel activity by binding the γ subunit's finger-thumb domain interface., Balchak DM, Thompson RN, Kashlan OB., J Biol Chem. October 19, 2018; 293 (42): 16217-16225.
Time-lapse imaging of cell death in cell culture and whole living organisms using turn-on deep-red fluorescent probes., Jarvis TS, Roland FM, Dubiak KM, Huber PW, Smith BD., J Mater Chem B. August 14, 2018; 6 (30): 4963-4971.
Toward an Ensemble View of Chromatosome Structure: A Paradigm Shift from One to Many., Öztürk MA, Cojocaru V, Wade RC., Structure. August 7, 2018; 26 (8): 1050-1057.

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