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Transcriptional regulator PRDM12 is essential for human pain perception., Chen YC, Auer-Grumbach M, Matsukawa S, Zitzelsberger M, Themistocleous AC, Strom TM, Samara C, Moore AW, Cho LT, Young GT, Weiss C, Schabhüttl M, Stucka R, Schmid AB, Parman Y, Graul-Neumann L, Heinritz W, Passarge E, Watson RM, Hertz JM, Moog U, Baumgartner M, Valente EM, Pereira D, Restrepo CM, Katona I, Dusl M, Stendel C, Wieland T, Stafford F, Reimann F, von Au K, Finke C, Willems PJ, Nahorski MS, Shaikh SS, Carvalho OP, Nicholas AK, Karbani G, McAleer MA, Cilio MR, McHugh JC, Murphy SM, Irvine AD, Jensen UB, Windhager R, Weis J, Bergmann C, Rautenstrauss B, Baets J, De Jonghe P, Reilly MM, Kropatsch R, Kurth I, Chrast R, Michiue T, Bennett DL, Woods CG, Senderek J., Nat Genet. July 1, 2015; 47 (7): 803-8. ![]() |
The Scorpion Toxin Tf2 from Tityus fasciolatus Promotes Nav1.3 Opening., Camargos TS, Bosmans F, Rego SC, Mourão CB, Schwartz EF., PLoS One. June 5, 2015; 10 (6): e0128578. ![]() |
The Fanconi Anemia DNA Repair Pathway Is Regulated by an Interaction between Ubiquitin and the E2-like Fold Domain of FANCL., Miles JA, Frost MG, Carroll E, Rowe ML, Howard MJ, Sidhu A, Chaugule VK, Alpi AF, Walden H., J Biol Chem. August 21, 2015; 290 (34): 20995-21006. ![]() |
The structure of a contact-dependent growth-inhibition (CDI) immunity protein from Neisseria meningitidis MC58., Tan K, Johnson PM, Stols L, Boubion B, Eschenfeldt W, Babnigg G, Hayes CS, Joachimiak A, Goulding CW., Acta Crystallogr F Struct Biol Commun. June 1, 2015; 71 (Pt 6): 702-9. |
The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane., Loregger A, Grandl M, Mejías-Luque R, Allgäuer M, Degenhart K, Haselmann V, Oikonomou C, Hatzis P, Janssen KP, Nitsche U, Gradl D, van den Broek O, Destree O, Ulm K, Neumaier M, Kalali B, Jung A, Varela I, Schmid RM, Rad R, Busch DH, Gerhard M., Sci Signal. September 8, 2015; 8 (393): ra90. |
Toxic mechanisms of copper oxide nanoparticles in epithelial kidney cells., Thit A, Selck H, Bjerregaard HF., Toxicol In Vitro. August 1, 2015; 29 (5): 1053-9. |
Three Peptide Modulators of the Human Voltage-Gated Sodium Channel 1.7, an Important Analgesic Target, from the Venom of an Australian Tarantula., Chow CY, Cristofori-Armstrong B, Undheim EA, King GF, Rash LD., Toxins (Basel). June 30, 2015; 7 (7): 2494-513. ![]() |
The mechanism of DNA replication termination in vertebrates., Dewar JM, Budzowska M, Walter JC., Nature. September 17, 2015; 525 (7569): 345-50. ![]() |
The rhodopsin-guanylyl cyclase of the aquatic fungus Blastocladiella emersonii enables fast optical control of cGMP signaling., Scheib U, Stehfest K, Gee CE, Körschen HG, Fudim R, Oertner TG, Hegemann P., Sci Signal. August 11, 2015; 8 (389): rs8. |
TPX2 phosphorylation maintains metaphase spindle length by regulating microtubule flux., Fu J, Bian M, Xin G, Deng Z, Luo J, Guo X, Chen H, Wang Y, Jiang Q, Zhang C., J Cell Biol. August 3, 2015; 210 (3): 373-83. ![]() |
Transient receptor potential melastatin 3 is a phosphoinositide-dependent ion channel., Badheka D, Borbiro I, Rohacs T., J Gen Physiol. July 1, 2015; 146 (1): 65-77. ![]() |
The Conqueror Worm: recent advances with cholinergic anthelmintics and techniques excite research for better therapeutic drugs., Martin RJ, Puttachary S, Buxton SK, Verma S, Robertson AP., J Helminthol. July 1, 2015; 89 (4): 387-97. ![]() |
The Ran-GTP gradient spatially regulates XCTK2 in the spindle., Weaver LN, Ems-McClung SC, Chen SH, Yang G, Shaw SL, Walczak CE., Curr Biol. June 1, 2015; 25 (11): 1509-14. |
The active Hsc70/tau complex can be exploited to enhance tau turnover without damaging microtubule dynamics., Fontaine SN, Martin MD, Akoury E, Assimon VA, Borysov S, Nordhues BA, Sabbagh JJ, Cockman M, Gestwicki JE, Zweckstetter M, Dickey CA., Hum Mol Genet. July 15, 2015; 24 (14): 3971-81. |
Teaching and learning in a Xenopus research lab., Yan S., Lab Anim (NY). August 1, 2015; 44 (8): 327. |
Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32., Brennan MJ, Karcz J, Vaughn NR, Woolwine-Cunningham Y, DePriest AD, Escalona Y, Perez-Acle T, Skerrett IM., J Biol Chem. July 10, 2015; 290 (28): 17074-84. |
The polyglutamine-expanded androgen receptor has increased DNA binding and reduced transcriptional activity., Belikov S, Bott LC, Fischbeck KH, Wrange Ö., Biochem Biophys Rep. July 26, 2015; 3 134-139. ![]() |
The Human Acid-Sensing Ion Channel ASIC1a: Evidence for a Homotetrameric Assembly State at the Cell Surface., van Bemmelen MX, Huser D, Gautschi I, Schild L., PLoS One. August 4, 2015; 10 (8): e0135191. ![]() |
The Proto-oncogene Transcription Factor Ets1 Regulates Neural Crest Development through Histone Deacetylase 1 to Mediate Output of Bone Morphogenetic Protein Signaling., Wang C, Kam RK, Shi W, Xia Y, Chen X, Cao Y, Sun J, Du Y, Lu G, Chen Z, Chan WY, Chan SO, Deng Y, Zhao H., J Biol Chem. September 4, 2015; 290 (36): 21925-38. ![]() |
The role of folate metabolism in orofacial development and clefting., Wahl SE, Kennedy AE, Wyatt BH, Moore AD, Pridgen DE, Cherry AM, Mavila CB, Dickinson AJ., Dev Biol. September 1, 2015; 405 (1): 108-22. ![]() |
The Autophagy Receptor TAX1BP1 and the Molecular Motor Myosin VI Are Required for Clearance of Salmonella Typhimurium by Autophagy., Tumbarello DA, Manna PT, Allen M, Bycroft M, Arden SD, Kendrick-Jones J, Buss F., PLoS Pathog. October 1, 2015; 11 (10): e1005174. ![]() |
Toxicological aspects of photocatalytic degradation of selected xenobiotics with nano-sized Mn-doped TiO2., Ozmen M, Güngördü A, Erdemoglu S, Ozmen N, Asilturk M., Aquat Toxicol. August 1, 2015; 165 144-153. |
Trypanosoma brucei Bloodstream Forms Depend upon Uptake of myo-Inositol for Golgi Complex Phosphatidylinositol Synthesis and Normal Cell Growth., González-Salgado A, Steinmann M, Major LL, Sigel E, Reymond JL, Smith TK, Bütikofer P., Eukaryot Cell. June 1, 2015; 14 (6): 616-24. |
The Mosquito Repellent Citronellal Directly Potentiates Drosophila TRPA1, Facilitating Feeding Suppression., Du EJ, Ahn TJ, Choi MS, Kwon I, Kim HW, Kwon JY, Kang K., Mol Cells. October 1, 2015; 38 (10): 911-7. ![]() |
The Neurotoxic Effect of 13,19-Didesmethyl and 13-Desmethyl Spirolide C Phycotoxins Is Mainly Mediated by Nicotinic Rather Than Muscarinic Acetylcholine Receptors., Aráoz R, Ouanounou G, Iorga BI, Goudet A, Alili D, Amar M, Benoit E, Molgó J, Servent D., Toxicol Sci. September 1, 2015; 147 (1): 156-67. |
The Effect of WNK4 on the Na+-Cl- Cotransporter Is Modulated by Intracellular Chloride., Bazúa-Valenti S, Chávez-Canales M, Rojas-Vega L, González-Rodríguez X, Vázquez N, Rodríguez-Gama A, Argaiz ER, Melo Z, Plata C, Ellison DH, García-Valdés J, Hadchouel J, Gamba G., J Am Soc Nephrol. August 1, 2015; 26 (8): 1781-6. |
Toxicity Evaluation of a New Zn-Doped CuO Nanocomposite With Highly Effective Antibacterial Properties., Mantecca P, Moschini E, Bonfanti P, Fascio U, Perelshtein I, Lipovsky A, Chirico G, Bacchetta R, Del Giacco L, Colombo A, Gedanken A., Toxicol Sci. July 1, 2015; 146 (1): 16-30. |
The lidocaine metabolite N-ethylglycine has antinociceptive effects in experimental inflammatory and neuropathic pain., Werdehausen R, Mittnacht S, Bee LA, Minett MS, Armbruster A, Bauer I, Wood JN, Hermanns H, Eulenburg V., Pain. September 1, 2015; 156 (9): 1647-1659. ![]() |
The tadpole of the Lake Oku clawed frog Xenopus longipes (Anura; Pipidae)., Tapley B, Michaels CJ, Doherty-Bone TM., Zootaxa. July 7, 2015; 3981 (4): 597-600. |
The Link between Inactivation and High-Affinity Block of hERG1 Channels., Wu W, Gardner A, Sanguinetti MC., Mol Pharmacol. June 8, 2015; 87 (6): 1042-50. |
The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family., Kelwick R, Desanlis I, Wheeler GN, Edwards DR., Genome Biol. May 30, 2015; 16 (1): 113. ![]() |
Targeted Inhibition of Snail Activity in Breast Cancer Cells by Using a Co(III) -Ebox Conjugate., Vistain LF, Yamamoto N, Rathore R, Cha P, Meade TJ., Chembiochem. September 21, 2015; 16 (14): 2065-72. |
Three-dimensional, three-vector-component velocimetry of cilia-driven fluid flow using correlation-based approaches in optical coherence tomography., Huang BK, Gamm UA, Bhandari V, Khokha MK, Choma MA., Biomed Opt Express. August 24, 2015; 6 (9): 3515-38. |
The influence of allosteric modulators and transmembrane mutations on desensitisation and activation of α7 nicotinic acetylcholine receptors., Chatzidaki A, D'Oyley JM, Gill-Thind JK, Sheppard TD, Millar NS., Neuropharmacology. October 1, 2015; 97 75-85. ![]() |
The Effects of Simazine, a Chlorotriazine Herbicide, on the Expression of Genes in Developing Male Xenopus laevis., Sai L, Liu Y, Qu B, Yu G, Guo Q, Bo C, Xie L, Jia Q, Li Y, Li X, Ng JC, Peng C., Bull Environ Contam Toxicol. August 1, 2015; 95 (2): 157-63. |
The lysine demethylase LSD1 is required for nuclear envelope formation at the end of mitosis., Schooley A, Moreno-Andrés D, De Magistris P, Vollmer B, Antonin W., J Cell Sci. September 15, 2015; 128 (18): 3466-77. |
Turn Up the Volume: Uncovering Nucleus Size Control Mechanisms., Good MC., Dev Cell. June 8, 2015; 33 (5): 496-7. |
TRPV4 and AQP4 Channels Synergistically Regulate Cell Volume and Calcium Homeostasis in Retinal Müller Glia., Jo AO, Ryskamp DA, Phuong TT, Verkman AS, Yarishkin O, MacAulay N, Križaj D., J Neurosci. September 30, 2015; 35 (39): 13525-37. ![]() |
Tight Chk1 Levels Control Replication Cluster Activation in Xenopus., Platel M, Goldar A, Wiggins JM, Barbosa P, Libeau P, Priam P, Narassimprakash H, Grodzenski X, Marheineke K., PLoS One. June 5, 2015; 10 (6): e0129090. ![]() |
Transport proteins NHA1 and NHA2 are essential for survival, but have distinct transport modalities., Chintapalli VR, Kato A, Henderson L, Hirata T, Woods DJ, Overend G, Davies SA, Romero MF, Dow JA., Proc Natl Acad Sci U S A. September 15, 2015; 112 (37): 11720-5. |
The small leucine-rich repeat secreted protein Asporin induces eyes in Xenopus embryos through the IGF signalling pathway., Luehders K, Sasai N, Davaapil H, Kurosawa-Yoshida M, Hiura H, Brah T, Ohnuma S., Development. October 1, 2015; 142 (19): 3351-61. ![]() |
The mouse gene expression database: New features and how to use them effectively., Finger JH, Smith CM, Hayamizu TF, McCright IJ, Xu J, Eppig JT, Kadin JA, Richardson JE, Ringwald M., Genesis. August 1, 2015; 53 (8): 510-22. |
TPX2 as a novel prognostic biomarker for hepatocellular carcinoma., Liu Q, Tu K, Zhang H, Zheng X, Yao Y, Liu Q., Hepatol Res. August 1, 2015; 45 (8): 906-18. |
The GIPC1-Akt1 Pathway Is Required for the Specification of the Eye Field in Mouse Embryonic Stem Cells., La Torre A, Hoshino A, Cavanaugh C, Ware CB, Reh TA., Stem Cells. September 1, 2015; 33 (9): 2674-85. |
The repetitive portion of the Xenopus IgH Mu switch region mediates orientation-dependent class switch recombination., Zhang ZZ, Pannunzio NR, Lu Z, Hsu E, Yu K, Lieber MR., Mol Immunol. October 1, 2015; 67 (2 Pt B): 524-31. |
TcPho91 is a contractile vacuole phosphate sodium symporter that regulates phosphate and polyphosphate metabolism in Trypanosoma cruzi., Jimenez V, Docampo R., Mol Microbiol. September 1, 2015; 97 (5): 911-25. |
Temporally coordinated signals progressively pattern the anteroposterior and dorsoventral body axes., Tuazon FB, Mullins MC., Semin Cell Dev Biol. June 1, 2015; 42 118-33. ![]() |
The Role of Flexible Loops in Folding, Trafficking and Activity of Equilibrative Nucleoside Transporters., Aseervatham J, Tran L, Machaca K, Boudker O., PLoS One. September 1, 2015; 10 (9): e0136779. ![]() |
Two classes of regulatory subunits coassemble in the same BK channel and independently regulate gating., Gonzalez-Perez V, Xia XM, Lingle CJ., Nat Commun. September 21, 2015; 6 8341. ![]() |
TGF-β Signaling Regulates the Differentiation of Motile Cilia., Tözser J, Earwood R, Kato A, Brown J, Tanaka K, Didier R, Megraw TL, Blum M, Kato Y., Cell Rep. May 19, 2015; 11 (7): 1000-7. ![]() |
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