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Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors., Kaminski MM, Tosic J, Kresbach C, Engel H, Klockenbusch J, Müller AL, Pichler R, Grahammer F, Kretz O, Huber TB, Walz G, Arnold SJ, Lienkamp SS., Nat Cell Biol. December 1, 2016; 18 (12): 1269-1280.
Developmental and Thyroid Hormone Regulation of the DNA Methyltransferase 3a Gene in Xenopus Tadpoles., Kyono Y, Sachs LM, Bilesimo P, Wen L, Denver RJ., Endocrinology. December 1, 2016; 157 (12): 4961-4972.
Dominant KCNA2 mutation causes episodic ataxia and pharmacoresponsive epilepsy., Corbett MA, Bellows ST, Li M, Carroll R, Micallef S, Carvill GL, Myers CT, Howell KB, Maljevic S, Lerche H, Gazina EV, Mefford HC, Bahlo M, Berkovic SF, Petrou S, Scheffer IE, Gecz J., Neurology. November 8, 2016; 87 (19): 1975-1984.
Distinct intracellular Ca2+ dynamics regulate apical constriction and differentially contribute to neural tube closure., Suzuki M, Sato M, Koyama H, Hara Y, Hayashi K, Yasue N, Imamura H, Fujimori T, Nagai T, Campbell RE, Ueno N., Development. April 1, 2017; 144 (7): 1307-1316.
Deletion of cytosolic gating ring decreases gate and voltage sensor coupling in BK channels., Zhang G, Geng Y, Jin Y, Shi J, McFarland K, Magleby KL, Salkoff L, Cui J., J Gen Physiol. March 6, 2017; 149 (3): 373-387.
Delamination of neural crest cells requires transient and reversible Wnt inhibition mediated by Dact1/2., Rabadán MA, Herrera A, Fanlo L, Usieto S, Carmona-Fontaine C, Barriga EH, Mayor R, Pons S, Martí E., Development. June 15, 2016; 143 (12): 2194-205.
Dominant-negative Gα subunits are a mechanism of dysregulated heterotrimeric G protein signaling in human disease., Marivin A, Leyme A, Parag-Sharma K, DiGiacomo V, Cheung AY, Nguyen LT, Dominguez I, Garcia-Marcos M., Sci Signal. April 12, 2016; 9 (423): ra37.
Deciphering the function of the CNGB1b subunit in olfactory CNG channels., Nache V, Wongsamitkul N, Kusch J, Zimmer T, Schwede F, Benndorf K., Sci Rep. July 11, 2016; 6 29378.
Direct interaction of the resistance to inhibitors of cholinesterase type 3 protein with the serotonin receptor type 3A intracellular domain., Nishtala SN, Mnatsakanyan N, Pandhare A, Leung C, Jansen M., J Neurochem. May 1, 2016; 137 (4): 528-38.
DDT exposure of frogs: A case study from Limpopo Province, South Africa., Viljoen IM, Bornman R, Bouwman H., Chemosphere. September 1, 2016; 159 335-341.
Development of Erythroid Progenitors under Erythropoietin Stimulation in Xenopus laevis Larval Liver., Okui T, Hosozawa S, Kohama S, Fujiyama S, Maekawa S, Muto H, Kato T., Zoolog Sci. December 1, 2016; 33 (6): 575-582.
Dynamic properties of calcium-activated chloride currents in Xenopus laevis oocytes., M De la Fuente I, Malaina I, Pérez-Samartín A, Boyano MD, Pérez-Yarza G, Bringas C, Villarroel Á, Fedetz M, Arellano R, Cortes JM, Martínez L., Sci Rep. February 13, 2017; 7 41791.
Deep-brain photoreception links luminance detection to motor output in Xenopus frog tadpoles., Currie SP, Doherty GH, Sillar KT., Proc Natl Acad Sci U S A. May 24, 2016; 113 (21): 6053-8.
Differential Effects of Quercetin and Quercetin Glycosides on Human α7 Nicotinic Acetylcholine Receptor-Mediated Ion Currents., Lee BH, Choi SH, Kim HJ, Jung SW, Hwang SH, Pyo MK, Rhim H, Kim HC, Kim HK, Lee SM, Nah SY., Biomol Ther (Seoul). July 1, 2016; 24 (4): 410-7.
Developing Xenopus embryos recover by compacting and expelling single wall carbon nanotubes., Holt BD, Shawky JH, Dahl KN, Davidson LA, Islam MF., J Appl Toxicol. April 1, 2016; 36 (4): 579-85.
Direct activation of GABAA receptors by substances in the organic acid fraction of Japanese sake., Izu H, Shigemori K, Eguchi M, Kawane S, Fujii S, Kitamura Y, Aoshima H, Yamada Y., Food Chem. January 1, 2017; 214 354-359.
Distortion of histone octamer core promotes nucleosome mobilization by a chromatin remodeler., Sinha KK, Gross JD, Narlikar GJ., Science. January 20, 2017; 355 (6322):
DMRTA2 (DMRT5) is mutated in a novel cortical brain malformation., Urquhart JE, Beaman G, Byers H, Roberts NA, Chervinsky E, O'Sullivan J, Pilz D, Fry A, Williams SG, Bhaskar SS, Khayat M, Simanovsky N, Shachar IB, Shalev SA, Newman WG., Clin Genet. June 1, 2016; 89 (6): 724-7.
Discovering novel phenotypes with automatically inferred dynamic models: a partial melanocyte conversion in Xenopus., Lobo D, Lobikin M, Levin M., Sci Rep. January 27, 2017; 7 41339.
Delineating the GRIN1 phenotypic spectrum: A distinct genetic NMDA receptor encephalopathy., Lemke JR, Geider K, Helbig KL, Heyne HO, Schütz H, Hentschel J, Courage C, Depienne C, Nava C, Heron D, Møller RS, Hjalgrim H, Lal D, Neubauer BA, Nürnberg P, Thiele H, Kurlemann G, Arnold GL, Bhambhani V, Bartholdi D, Pedurupillay CR, Misceo D, Frengen E, Strømme P, Dlugos DJ, Doherty ES, Bijlsma EK, Ruivenkamp CA, Hoffer MJ, Goldstein A, Rajan DS, Narayanan V, Ramsey K, Belnap N, Schrauwen I, Richholt R, Koeleman BP, Sá J, Mendonça C, de Kovel CG, Weckhuysen S, Hardies K, De Jonghe P, De Meirleir L, Milh M, Badens C, Lebrun M, Busa T, Francannet C, Piton A, Riesch E, Biskup S, Vogt H, Dorn T, Helbig I, Michaud JL, Laube B, Syrbe S., Neurology. June 7, 2016; 86 (23): 2171-8.
Distribution of single wall carbon nanotubes in the Xenopus laevis embryo after microinjection., Holt BD, Shawky JH, Dahl KN, Davidson LA, Islam MF., J Appl Toxicol. April 1, 2016; 36 (4): 568-78.
Design of Light-Sensitive NMDARs by Genetically Encoded Photo-Cross-Linkers., Tian M, Ye S., Methods Mol Biol. January 1, 2017; 1677 185-197.
Disruption of a putative intersubunit electrostatic bond enhances agonist efficacy at the human α1 glycine receptor., Welsh BT, Todorovic J, Kirson D, Allen HM, Bayly MD, Mihic SJ., Brain Res. February 15, 2017; 1657 148-155.
Determining the optimal developmental stages of Xenopus laevis for initiating exposures to chemicals for sensitively detecting their feminizing effects on gonadal differentiation., Li YY, Chen J, Qin ZF., Aquat Toxicol. October 1, 2016; 179 134-42.
DHCR7: A vital enzyme switch between cholesterol and vitamin D production., Prabhu AV, Luu W, Li D, Sharpe LJ, Brown AJ., Prog Lipid Res. October 1, 2016; 64 138-151.
Development of yeast reporter assays for the enhanced detection of environmental ligands of thyroid hormone receptors α and β from Xenopus tropicalis., Matsui S, Ito-Harashima S, Sugimoto Y, Takada E, Shiizaki K, Kawanishi M, Yagi T., Toxicol In Vitro. December 1, 2016; 37 15-24.
Direct non transcriptional role of NF-Y in DNA replication., Benatti P, Belluti S, Miotto B, Neusiedler J, Dolfini D, Drac M, Basile V, Schwob E, Mantovani R, Blow JJ, Imbriano C., Biochim Biophys Acta. April 1, 2016; 1863 (4): 673-85.
Development of the Larval Amphibian Growth and Development Assay: Effects of benzophenone-2 exposure in Xenopus laevis from embryo to juvenile., Haselman JT, Sakurai M, Watanabe N, Goto Y, Onishi Y, Ito Y, Onoda Y, Kosian PA, Korte JJ, Johnson RD, Iguchi T, Degitz SJ., J Appl Toxicol. December 1, 2016; 36 (12): 1651-1661.
Development of GABAA Receptor Subtype-Selective Imidazobenzodiazepines as Novel Asthma Treatments., Forkuo GS, Guthrie ML, Yuan NY, Nieman AN, Kodali R, Jahan R, Stephen MR, Yocum GT, Treven M, Poe MM, Li G, Yu OB, Hartzler BD, Zahn NM, Ernst M, Emala CW, Stafford DC, Cook JM, Arnold LA., Mol Pharm. June 6, 2016; 13 (6): 2026-38.
Dissociable effects of the prodrug phendimetrazine and its metabolite phenmetrazine at dopamine transporters., Solis E, Suyama JA, Lazenka MF, DeFelice LJ, Negus SS, Blough BE, Banks ML., Sci Rep. August 12, 2016; 6 31385.
Differential Inhibition of Water and Ion Channel Activities of Mammalian Aquaporin-1 by Two Structurally Related Bacopaside Compounds Derived from the Medicinal Plant Bacopa monnieri., Pei JV, Kourghi M, De Ieso ML, Campbell EM, Dorward HS, Hardingham JE, Yool AJ., Mol Pharmacol. October 29, 2016; 90 (4): 496-507.
Direct Regulation of Histidine Ammonia-Lyase 2 Gene by Thyroid Hormone in the Developing Adult Intestinal Stem Cells., Luu N, Fu L, Fujimoto K, Shi YB., Endocrinology. April 1, 2017; 158 (4): 1022-1033.
Developmental changes in head movement kinematics during swimming in Xenopus laevis tadpoles., Hänzi S, Straka H., J Exp Biol. January 15, 2017; 220 (Pt 2): 227-236.
Diversity of Nicotinic Acetylcholine Receptor Positive Allosteric Modulators Revealed by Mutagenesis and a Revised Structural Model., Newcombe J, Chatzidaki A, Sheppard TD, Topf M, Millar NS., Mol Pharmacol. February 1, 2017; 93 (2): 128-140.
Differences in mobility at the range edge of an expanding invasive population of Xenopus laevis in the west of France., Louppe V, Courant J, Herrel A., J Exp Biol. January 15, 2017; 220 (Pt 2): 278-283.
Direct Binding to Replication Protein A (RPA)-coated Single-stranded DNA Allows Recruitment of the ATR Activator TopBP1 to Sites of DNA Damage., Acevedo J, Yan S, Michael WM., J Biol Chem. June 17, 2016; 291 (25): 13124-31.
Discrete Mesh Approach in Morphogenesis Modelling: the Example of Gastrulation., Demongeot J, Lontos A, Promayon E., Acta Biotheor. December 1, 2016; 64 (4): 427-446.
Developmental changes in drug-metabolizing enzyme expression during metamorphosis of Xenopus tropicalis., Mori J, Sanoh S, Kashiwagi K, Hanada H, Shigeta M, Suzuki KT, Yamamoto T, Kotake Y, Sugihara K, Kitamura S, Kashiwagi A, Ohta S., J Toxicol Sci. January 1, 2017; 42 (5): 605-613.
Disrupting effects of azocyclotin to the hypothalamo-pituitary-gonadal axis and reproduction of Xenopus laevis., Li S, Li M, Gui W, Wang Q, Zhu G., Aquat Toxicol. April 1, 2017; 185 121-128.
Data on microRNAs and microRNA-targeted mRNAs in Xenopus ectoderm., Shah VV, Soibam B, Ritter RA, Benham A, Oomen J, Sater AK., Data Brief. October 14, 2016; 9 699-703.
Dietary exposure to polybrominated diphenyl ether 47 (BDE-47) inhibits development and alters thyroid hormone-related gene expression in the brain of Xenopus laevis tadpoles., Yost AT, Thornton LM, Venables BJ, Sellin Jeffries MK., Environ Toxicol Pharmacol. December 1, 2016; 48 237-244.
Distinct Hypnotic Recoveries After Infusions of Methoxycarbonyl Etomidate and Cyclopropyl Methoxycarbonyl Metomidate: The Role of the Metabolite., Pejo E, Liu J, Lin X, Raines DE., Anesth Analg. April 1, 2016; 122 (4): 1008-14.
Diclofenac can exhibit estrogenic modes of action in male Xenopus laevis, and affects the hypothalamus-pituitary-gonad axis and mating vocalizations., Efosa NJ, Kleiner W, Kloas W, Hoffmann F., Chemosphere. April 1, 2017; 173 69-77.
Dysregulation of a potassium channel, THIK-1, targeted by caspase-8 accelerates cell shrinkage., Sakamaki K, Ishii TM, Sakata T, Takemoto K, Takagi C, Takeuchi A, Morishita R, Takahashi H, Nozawa A, Shinoda H, Chiba K, Sugimoto H, Saito A, Tamate S, Satou Y, Jung SK, Matsuoka S, Koyamada K, Sawasaki T, Nagai T, Ueno N., Biochim Biophys Acta. November 1, 2016; 1863 (11): 2766-2783.
Development of the Larval Amphibian Growth and Development Assay: effects of chronic 4-tert-octylphenol or 17β-trenbolone exposure in Xenopus laevis from embryo to juvenile., Haselman JT, Kosian PA, Korte JJ, Olmstead AW, Iguchi T, Johnson RD, Degitz SJ., J Appl Toxicol. December 1, 2016; 36 (12): 1639-1650.
Dynamic heterogeneity and non-Gaussian statistics for acetylcholine receptors on live cell membrane., He W, Song H, Su Y, Geng L, Ackerson BJ, Peng HB, Tong P., Nat Commun. May 26, 2016; 7 11701.
De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development., Gordon CT, Xue S, Yigit G, Filali H, Chen K, Rosin N, Yoshiura KI, Oufadem M, Beck TJ, McGowan R, Magee AC, Altmüller J, Dion C, Thiele H, Gurzau AD, Nürnberg P, Meschede D, Mühlbauer W, Okamoto N, Varghese V, Irving R, Sigaudy S, Williams D, Ahmed SF, Bonnard C, Kong MK, Ratbi I, Fejjal N, Fikri M, Elalaoui SC, Reigstad H, Bole-Feysot C, Nitschké P, Ragge N, Lévy N, Tunçbilek G, Teo AS, Cunningham ML, Sefiani A, Kayserili H, Murphy JM, Chatdokmaiprai C, Hillmer AM, Wattanasirichaigoon D, Lyonnet S, Magdinier F, Javed A, Blewitt ME, Amiel J, Wollnik B, Reversade B., Nat Genet. February 1, 2017; 49 (2): 249-255.
Dipicrylamine Modulates GABAρ1 Receptors through Interactions with Residues in the TM4 and Cys-Loop Domains., Limon A, Estrada-Mondragón A, Ruiz JM, Miledi R., Mol Pharmacol. April 11, 2016; 89 (4): 446-56.
Delineation of the functional properties and the mechanism of action of TMPPAA, an allosteric agonist and positive allosteric modulator of 5-HT3 receptors., Gasiorek A, Trattnig SM, Ahring PK, Kristiansen U, Frølund B, Frederiksen K, Jensen AA., Biochem Pharmacol. June 15, 2016; 110-111 92-108.
Dissecting the pre-placodal transcriptome to reveal presumptive direct targets of Six1 and Eya1 in cranial placodes., Riddiford N, Schlosser G., Elife. August 31, 2016; 5

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