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J Neurol
2023 Jan 01;2701:57-70. doi: 10.1007/s00415-022-11311-8.
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Homeostatic plasticity of eye movement performance in Xenopus tadpoles following prolonged visual image motion stimulation.
Forsthofer M
,
Straka H
.
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Visual image motion-driven ocular motor behaviors such as the optokinetic reflex (OKR) provide sensory feedback for optimizing gaze stability during head/body motion. The performance of this visuo-motor reflex is subject to plastic alterations depending on requirements imposed by specific eco-physiological or developmental circumstances. While visuo-motor plasticity can be experimentally induced by various combinations of motion-related stimuli, the extent to which such evoked behavioral alterations contribute to the behavioral demands of an environment remains often obscure. Here, we used isolated preparations of Xenopus laevis tadpoles to assess the extent and ontogenetic dependency of visuo-motor plasticity during prolonged visual image motion. While a reliable attenuation of large OKR amplitudes can be induced already in young larvae, a robust response magnitude-dependent bidirectional plasticity is present only at older developmental stages. The possibility of older larvae to faithfully enhance small OKR amplitudes coincides with the developmental maturation of inferior olivary-Purkinje cell signal integration. This conclusion was supported by the loss of behavioral plasticity following transection of the climbing fiber pathway and by the immunohistochemical demonstration of a considerable volumetric extension of the Purkinje cell dendritic area between the two tested stages. The bidirectional behavioral alterations with different developmental onsets might functionally serve to standardize the motor output, comparable to the known differential adaptability of vestibulo-ocular reflexes in these animals. This homeostatic plasticity potentially equilibrates the working range of ocular motor behaviors during altered visuo-vestibular conditions or prolonged head/body motion to fine-tune resultant eye movements.
Bacqué-Cazenave,
Temporal Relationship of Ocular and Tail Segmental Movements Underlying Locomotor-Induced Gaze Stabilization During Undulatory Swimming in Larval Xenopus.
2018, Pubmed,
Xenbase
Bacqué-Cazenave,
Temporal Relationship of Ocular and Tail Segmental Movements Underlying Locomotor-Induced Gaze Stabilization During Undulatory Swimming in Larval Xenopus.
2018,
Pubmed
,
Xenbase
Bacqué-Cazenave,
Locomotion-induced ocular motor behavior in larval Xenopus is developmentally tuned by visuo-vestibular reflexes.
2022,
Pubmed
,
Xenbase
Beck,
Quantifying the ontogeny of optokinetic and vestibuloocular behaviors in zebrafish, medaka, and goldfish.
2004,
Pubmed
Beraneck,
Asymmetric recovery in cerebellar-deficient mice following unilateral labyrinthectomy.
2008,
Pubmed
Boyden,
Cerebellum-dependent learning: the role of multiple plasticity mechanisms.
2004,
Pubmed
Brooks,
Learning to expect the unexpected: rapid updating in primate cerebellum during voluntary self-motion.
2015,
Pubmed
Cochran,
Basic optokinetic-ocular reflex pathways in the frog.
1984,
Pubmed
Collewijn,
The vestibulo-ocular reflex: is it an independent subsystem?
1989,
Pubmed
Collewijn,
Adaptation of optokinetic and vestibulo-ocular reflexes to modified visual input in the rabbit.
1979,
Pubmed
Cullen,
Vestibular processing during natural self-motion: implications for perception and action.
2019,
Pubmed
Dietrich,
Prolonged vestibular stimulation induces homeostatic plasticity of the vestibulo-ocular reflex in larval Xenopus laevis.
2016,
Pubmed
,
Xenbase
Dow,
Analysis and neural network modeling of the nonlinear correlates of habituation in the vestibulo-ocular reflex.
1998,
Pubmed
Faulstich,
Comparison of plasticity and development of mouse optokinetic and vestibulo-ocular reflexes suggests differential gain control mechanisms.
2004,
Pubmed
França de Barros,
Long term visuo-vestibular mismatch in freely behaving mice differentially affects gaze stabilizing reflexes.
2020,
Pubmed
Galliano,
Silencing the majority of cerebellar granule cells uncovers their essential role in motor learning and consolidation.
2013,
Pubmed
Giolli,
The accessory optic system: basic organization with an update on connectivity, neurochemistry, and function.
2006,
Pubmed
Gittis,
Intrinsic and synaptic plasticity in the vestibular system.
2006,
Pubmed
Glasauer,
Low Gain Values of the Vestibulo-Ocular Reflex Can Optimize Retinal Image Slip.
2022,
Pubmed
,
Xenbase
Gravot,
It's not all black and white: visual scene parameters influence optokinetic reflex performance in Xenopus laevis tadpoles.
2017,
Pubmed
,
Xenbase
Gruberg,
Basal optic complex in the frog (Rana pipiens): a physiological and HRP study.
1984,
Pubmed
Gutierrez-Castellanos,
Impact of aging on long-term ocular reflex adaptation.
2013,
Pubmed
Horn,
Functional Organization of Extraocular Motoneurons and Eye Muscles.
2021,
Pubmed
Inoshita,
Occurrence of long-term depression in the cerebellar flocculus during adaptation of optokinetic response.
2018,
Pubmed
Jäger,
Vestibular habituation in man and monkey during sinusoidal rotation.
1981,
Pubmed
Kimpo,
Gating of neural error signals during motor learning.
2014,
Pubmed
Knorr,
Image motion with color contrast suffices to elicit an optokinetic reflex in Xenopus laevis tadpoles.
2021,
Pubmed
,
Xenbase
Knorr,
I spy with my little eye: a simple behavioral assay to test color sensitivity on digital displays.
2018,
Pubmed
,
Xenbase
Kodama,
Adaptive Acceleration of Visually Evoked Smooth Eye Movements in Mice.
2016,
Pubmed
Lambert,
Semicircular canal size determines the developmental onset of angular vestibuloocular reflexes in larval Xenopus.
2008,
Pubmed
,
Xenbase
Lambert,
Stabilization of Gaze during Early Xenopus Development by Swimming-Related Utricular Signals.
2020,
Pubmed
,
Xenbase
Land,
The roles of vision and eye movements in the control of activities of daily living.
1999,
Pubmed
Lev-Ram,
A new form of cerebellar long-term potentiation is postsynaptic and depends on nitric oxide but not cAMP.
2002,
Pubmed
Linden,
Long-term synaptic depression.
1995,
Pubmed
Lisberger,
Signals used to compute errors in monkey vestibuloocular reflex: possible role of flocculus.
1984,
Pubmed
Lisberger,
The Rules of Cerebellar Learning: Around the Ito Hypothesis.
2021,
Pubmed
Markov,
A cerebellar internal model calibrates a feedback controller involved in sensorimotor control.
2021,
Pubmed
Marr,
A theory of cerebellar cortex.
1969,
Pubmed
Marsh,
Normal and adapted visuooculomotor reflexes in goldfish.
1997,
Pubmed
Masseck,
Comparative neurobiology of the optokinetic reflex.
2009,
Pubmed
McKenna,
Accessory optic system and pretectum of birds: comparisons with those of other vertebrates.
1985,
Pubmed
Miki,
Velocity storage mechanism drives a cerebellar clock for predictive eye velocity control.
2020,
Pubmed
Miki,
Cerebellar Role in Predictive Control of Eye Velocity Initiation and Termination.
2018,
Pubmed
Miles,
Long-term adaptive changes in primate vestibuloocular reflex. I. Behavioral observations.
1980,
Pubmed
Miyoshi,
Studies on optokinetic habituation.
1973,
Pubmed
Nguyen-Vu,
Cerebellar Purkinje cell activity drives motor learning.
2013,
Pubmed
Pan,
Shrinkage-mediated imaging of entire organs and organisms using uDISCO.
2016,
Pubmed
Pastor,
Cerebellar role in adaptation of the goldfish vestibuloocular reflex.
1994,
Pubmed
Pham,
Differential effects of inferior olive lesion on vestibulo-ocular and optokinetic motor learning.
2020,
Pubmed
Rowan,
Graded Control of Climbing-Fiber-Mediated Plasticity and Learning by Inhibition in the Cerebellum.
2018,
Pubmed
Schneider,
NIH Image to ImageJ: 25 years of image analysis.
2012,
Pubmed
Shin,
Signals and learning rules guiding oculomotor plasticity.
2014,
Pubmed
Sillar,
The post-embryonic development of cell properties and synaptic drive underlying locomotor rhythm generation in Xenopus larvae.
1992,
Pubmed
,
Xenbase
Soupiadou,
Acute consequences of a unilateral VIIIth nerve transection on vestibulo-ocular and optokinetic reflexes in Xenopus laevis tadpoles.
2020,
Pubmed
,
Xenbase
Straka,
A New Perspective on Predictive Motor Signaling.
2018,
Pubmed
Straka,
Rhombomeric organization of vestibular pathways in larval frogs.
2001,
Pubmed
Straka,
Preservation of segmental hindbrain organization in adult frogs.
2006,
Pubmed
Straka,
Ontogenetic rules and constraints of vestibulo-ocular reflex development.
2010,
Pubmed
Straka,
Basic organization principles of the VOR: lessons from frogs.
2004,
Pubmed
Wakita,
Differential regulations of vestibulo-ocular reflex and optokinetic response by β- and α2-adrenergic receptors in the cerebellar flocculus.
2017,
Pubmed
Yang,
Learning on multiple timescales in smooth pursuit eye movements.
2010,
Pubmed
du Lac,
Learning and memory in the vestibulo-ocular reflex.
1995,
Pubmed
van Alphen,
Cerebellar LTD facilitates but is not essential for long-term adaptation of the vestibulo-ocular reflex.
2002,
Pubmed
van der Linden,
Development of olivocerebellar fibers in the clawed toad, Xenopus laevis: a light and electron microscopical HRP study.
1990,
Pubmed
,
Xenbase
