XB-ART-23719FEBS Lett 1992 May 25;3031:81-4.
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Multiple genes for Xenopus activin receptor expressed during early embryogenesis.
Four distinct cDNAs for activin receptor designated as XSTK2, 3, 8 and 9 have been cloned from a Xenopus laevis cDNA library. The protein structures deduced from the cDNAs have shown that they all have a putative extracellular ligand-binding domain, a single transmembrane domain and cytoplasmic Ser/Thr kinase domain, except that XSTK2 is extremely similar to the XSTK3 gene but lacks a carboxyl-terminal part of the kinase motif. Northern blot analysis showed that all transcripts are maternally inherited. The levels of transcript for XSTK2, 3 and 8 appeared to fluctuate during early development while those for XSTK9 maintain constant.
PubMed ID: 1317302
Species referenced: Xenopus laevis
Genes referenced: acvr2a cdkl5 stk3