Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-23176
Brain Res Dev Brain Res 1992 Nov 20;701:134-8. doi: 10.1016/0165-3806(92)90111-9.
Show Gene links Show Anatomy links

Expression of carnosine-like immunoreactivity during retinal development in the clawed frog (Xenopus laevis).

Pognetto MS , Panzanelli P , Fasolo A , Cantino D .


???displayArticle.abstract???
The development of neurons immunoreactive to carnosine (beta-alanyl-L-histidine) was studied in the retina of Xenopus laevis during the premetamorphic period. Carnosine-like immunoreactivity was detected in photoreceptors from stage 39/40 (according to Nieuwkoop and Faber [Normal Tables of Xenopus laevis (Daudin), Elsevier, Amsterdam, 1956]) and in bipolar cells and their processes in the inner plexiform layer from stage 44/45. At all the developmental stages studied, neuroepithelial cells at the ciliary margin were completely unstained, suggesting that carnosine is only present in postmitotic retinal neurons. This study demonstrates a correlation between the times of appearance of carnosine-like immunoreactivity during retinal development and the onset of visual function.

???displayArticle.pubmedLink??? 1473272
???displayArticle.link??? Brain Res Dev Brain Res