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Proc Natl Acad Sci U S A 1995 Mar 14;926:1975-8.
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Amphibian development in the virtual absence of gravity.

Souza KA , Black SD , Wassersug RJ .

To test whether gravity is required for normal amphibian development, Xenopus laevis females were induced to ovulate aboard the orbiting Space Shuttle. Eggs were fertilized in vitro, and although early embryonic stages showed some abnormalities, the embryos were able to regulate and produce nearly normal larvae. These results demonstrate that a vertebrate can ovulate in the virtual absence of gravity and that the eggs can develop to a free-living stage.

PubMed ID: 7892210
PMC ID: PMC42405
Article link: Proc Natl Acad Sci U S A

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References [+] :
Black, Experimental control of the site of embryonic axis formation in Xenopus laevis eggs centrifuged before first cleavage. 1985, Pubmed, Xenbase