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Gene Expr Patterns 2005 Jun 01;55:601-8. doi: 10.1016/j.modgep.2005.03.007.
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Evi-1 expression in Xenopus.

Mead PE , Parganas E , Ohtsuka S , Morishita K , Gamer L , Kuliyev E , Wright CV , Ihle JN .

The Evi-1 gene was first identified as a site for viral integration in murine myeloid leukemia. Evi-1 is a zinc finger transcription factor that has been implicated in the development of myeloid neoplasia. In humans, disruption of the Evi-1 locus, by chromosomal rearrangements, is associated with myeloid leukemia and myelodyplastic syndromes. Here, we report the cloning and developmental pattern of expression of Xenopus Evi-1. xEvi-1 is expressed during oogenesis and during embryonic development. In situ hydridization reveals that xEvi-1 has a dynamic expression profile during early embryonic development. Expression of Evi-1 is detected by in situ hybridization in the pronephric tissue, the brain and in neural crest derivatives of the head and neck.

PubMed ID: 15905132
Article link: Gene Expr Patterns
Grant support: [+]

Species referenced: Xenopus laevis
Genes referenced: egr2 mecom pax8 runx1 wls

Article Images: [+] show captions