Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-14976
Mech Dev 1998 Apr 01;731:107-16.
Show Gene links Show Anatomy links

Structure and expression of Wnt13, a novel mouse Wnt2 related gene.

Zakin LD , Mazan S , Maury M , Martin N , Guénet JL , Brûlet P .


???displayArticle.abstract???
We have identified a novel mouse member of the Wnt family, Wnt13. Among mouse Wnt genes, Wnt13 is most closely related to Wnt2. Sequence comparisons and chromosomal localization strongly suggest that Wnt13, rather than Wnt2, is the mouse orthologue of both the human WNT13 and Xenopus XWnt2 genes. Wnt13 is expressed in the embryonic mesoderm during gastrulation. At later stages, transcripts are detected in the dorsal midline of the diencephalon and mesencephalon, the heart primordia, the periphery of the lung bud and the otic and optic vesicles. These data suggest that Wnt13 function might partially overlap with those of other Wnt genes in the cell signaling mechanisms controlling mesoderm specification during gastrulation and some aspects of brain, heart and lung formation.

???displayArticle.pubmedLink??? 9545553
???displayArticle.link??? Mech Dev


Species referenced: Xenopus
Genes referenced: wnt2