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XB-ART-8326
Science 2001 Oct 19;2945542:530-1. doi: 10.1126/science.1066282.
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Development. Endothelium--chicken soup for the endoderm.

Bahary N , Zon LI .


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Endothelial cells in blood vessels are known to be important during the later stages of organ development in the embryo. However, their involvement at the induction stage of organ formation has not been previously documented. As Bahary and Zon explain in their Perspective, new work demonstrates that endothelial cells secrete factors early in development that induce embryonic endoderm to become liver or pancreas (Matsumoto et al., Lammert et al.).

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Species referenced: Xenopus
Genes referenced: tbx2

References [+] :
Lammert, Induction of pancreatic differentiation by signals from blood vessels. 2001, Pubmed, Xenbase