XB-ART-7549
Dev Genes Evol
2002 Feb 01;2121:47-9. doi: 10.1007/s00427-001-0199-7.
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Developmental expression of cardiac myosin-binding protein C in Xenopus.
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We have isolated the Xenopus homologue of cardiac myosin-binding protein C ( cMyBP-C) and describe its expression during early embryogenesis. cMyBP-C is expressed in both somites and heart at the time these tissues differentiate. Expression in the somites declines in older tadpoles. There is a high degree of conservation in residues where mutations causing hypertrophic cardiomyopathy have been identified in humans.
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